| Full name: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B | Alias Symbol: GnT-Ivb | ||
| Type: protein-coding gene | Cytoband: 5q35.3 | ||
| Entrez ID: 11282 | HGNC ID: HGNC:7048 | Ensembl Gene: ENSG00000161013 | OMIM ID: 604561 |
| Drug and gene relationship at DGIdb | |||
Expression of MGAT4B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MGAT4B | 11282 | 224598_at | 0.5340 | 0.2965 | |
| GSE20347 | MGAT4B | 11282 | 220189_s_at | -0.2320 | 0.0838 | |
| GSE23400 | MGAT4B | 11282 | 220189_s_at | 0.0583 | 0.4119 | |
| GSE26886 | MGAT4B | 11282 | 224598_at | 0.7725 | 0.0011 | |
| GSE29001 | MGAT4B | 11282 | 220189_s_at | -0.0557 | 0.7830 | |
| GSE38129 | MGAT4B | 11282 | 220189_s_at | 0.1215 | 0.5101 | |
| GSE45670 | MGAT4B | 11282 | 224598_at | -0.0408 | 0.7733 | |
| GSE63941 | MGAT4B | 11282 | 224598_at | -0.9830 | 0.0346 | |
| GSE77861 | MGAT4B | 11282 | 224598_at | -0.0556 | 0.8359 | |
| GSE97050 | MGAT4B | A_21_P0000202 | -0.0031 | 0.9954 | ||
| SRP007169 | MGAT4B | 11282 | RNAseq | -1.0050 | 0.0033 | |
| SRP008496 | MGAT4B | 11282 | RNAseq | -1.1410 | 0.0000 | |
| SRP064894 | MGAT4B | 11282 | RNAseq | 0.1793 | 0.2995 | |
| SRP133303 | MGAT4B | 11282 | RNAseq | 0.1144 | 0.5745 | |
| SRP159526 | MGAT4B | 11282 | RNAseq | 0.0570 | 0.8228 | |
| SRP193095 | MGAT4B | 11282 | RNAseq | -0.3730 | 0.1197 | |
| SRP219564 | MGAT4B | 11282 | RNAseq | 0.4222 | 0.4173 | |
| TCGA | MGAT4B | 11282 | RNAseq | -0.1345 | 0.0096 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by MGAT4B expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MGAT4B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MGAT4B | 11282 | 2 | 12 | 16 | |
| GSE20123 | MGAT4B | 11282 | 2 | 12 | 16 | |
| GSE43470 | MGAT4B | 11282 | 1 | 11 | 31 | |
| GSE46452 | MGAT4B | 11282 | 0 | 27 | 32 | |
| GSE47630 | MGAT4B | 11282 | 1 | 20 | 19 | |
| GSE54993 | MGAT4B | 11282 | 10 | 2 | 58 | |
| GSE54994 | MGAT4B | 11282 | 2 | 17 | 34 | |
| GSE60625 | MGAT4B | 11282 | 1 | 0 | 10 | |
| GSE74703 | MGAT4B | 11282 | 1 | 7 | 28 | |
| GSE74704 | MGAT4B | 11282 | 1 | 6 | 13 | |
| TCGA | MGAT4B | 11282 | 11 | 34 | 51 |
Total number of gains: 32; Total number of losses: 148; Total Number of normals: 308.
Somatic mutations of MGAT4B:
Generating mutation plots.
Highly correlated genes for MGAT4B:
Showing top 20/352 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MGAT4B | CSNK2A2 | 0.823825 | 3 | 0 | 3 |
| MGAT4B | THEM4 | 0.779522 | 3 | 0 | 3 |
| MGAT4B | LY75 | 0.777318 | 3 | 0 | 3 |
| MGAT4B | MDM2 | 0.776689 | 3 | 0 | 3 |
| MGAT4B | MAPKAPK5 | 0.773228 | 3 | 0 | 3 |
| MGAT4B | NOLC1 | 0.771289 | 3 | 0 | 3 |
| MGAT4B | SLC30A7 | 0.765539 | 3 | 0 | 3 |
| MGAT4B | GPR158 | 0.763409 | 3 | 0 | 3 |
| MGAT4B | NOL10 | 0.747779 | 3 | 0 | 3 |
| MGAT4B | DNTTIP1 | 0.746891 | 3 | 0 | 3 |
| MGAT4B | C12orf65 | 0.746611 | 3 | 0 | 3 |
| MGAT4B | LACTB | 0.738206 | 4 | 0 | 4 |
| MGAT4B | KDM5B | 0.737974 | 3 | 0 | 3 |
| MGAT4B | SPNS1 | 0.735056 | 3 | 0 | 3 |
| MGAT4B | WIPF2 | 0.734152 | 3 | 0 | 3 |
| MGAT4B | KIF3B | 0.731471 | 3 | 0 | 3 |
| MGAT4B | MED19 | 0.731258 | 3 | 0 | 3 |
| MGAT4B | PKP2 | 0.731218 | 3 | 0 | 3 |
| MGAT4B | HJURP | 0.730992 | 3 | 0 | 3 |
| MGAT4B | KIAA0930 | 0.72651 | 3 | 0 | 3 |
For details and further investigation, click here
