| Full name: phosphoribosyl pyrophosphate synthetase 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: Xp22.2 | ||
| Entrez ID: 5634 | HGNC ID: HGNC:9465 | Ensembl Gene: ENSG00000101911 | OMIM ID: 311860 |
| Drug and gene relationship at DGIdb | |||
Expression of PRPS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRPS2 | 5634 | 203401_at | 0.6625 | 0.1865 | |
| GSE20347 | PRPS2 | 5634 | 203401_at | 0.8406 | 0.0002 | |
| GSE23400 | PRPS2 | 5634 | 203401_at | 0.7884 | 0.0000 | |
| GSE26886 | PRPS2 | 5634 | 203401_at | 0.4530 | 0.0948 | |
| GSE29001 | PRPS2 | 5634 | 203401_at | 0.6779 | 0.0598 | |
| GSE38129 | PRPS2 | 5634 | 203401_at | 0.5752 | 0.0010 | |
| GSE45670 | PRPS2 | 5634 | 203401_at | 0.5408 | 0.0077 | |
| GSE53622 | PRPS2 | 5634 | 36820 | 0.4988 | 0.0000 | |
| GSE53624 | PRPS2 | 5634 | 36820 | 0.4893 | 0.0000 | |
| GSE63941 | PRPS2 | 5634 | 230352_at | 3.4306 | 0.0001 | |
| GSE77861 | PRPS2 | 5634 | 203401_at | 0.3754 | 0.3558 | |
| GSE97050 | PRPS2 | 5634 | A_23_P96641 | 0.8560 | 0.0782 | |
| SRP007169 | PRPS2 | 5634 | RNAseq | 0.9367 | 0.0843 | |
| SRP008496 | PRPS2 | 5634 | RNAseq | 1.0534 | 0.0010 | |
| SRP064894 | PRPS2 | 5634 | RNAseq | 0.6916 | 0.0002 | |
| SRP133303 | PRPS2 | 5634 | RNAseq | 0.8031 | 0.0040 | |
| SRP159526 | PRPS2 | 5634 | RNAseq | 0.2335 | 0.2163 | |
| SRP193095 | PRPS2 | 5634 | RNAseq | 0.3133 | 0.0351 | |
| SRP219564 | PRPS2 | 5634 | RNAseq | 0.9343 | 0.0202 | |
| TCGA | PRPS2 | 5634 | RNAseq | -0.0467 | 0.3946 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by PRPS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRPS2:
No record found for this gene.
Somatic mutations of PRPS2:
Generating mutation plots.
Highly correlated genes for PRPS2:
Showing top 20/1336 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRPS2 | AK2 | 0.794484 | 3 | 0 | 3 |
| PRPS2 | GINS3 | 0.785233 | 4 | 0 | 4 |
| PRPS2 | ALG1 | 0.780377 | 3 | 0 | 3 |
| PRPS2 | CHCHD5 | 0.776842 | 3 | 0 | 3 |
| PRPS2 | RNF126 | 0.756559 | 3 | 0 | 3 |
| PRPS2 | ATP2C2 | 0.747211 | 3 | 0 | 3 |
| PRPS2 | LEMD2 | 0.745824 | 3 | 0 | 3 |
| PRPS2 | SAMD1 | 0.742482 | 3 | 0 | 3 |
| PRPS2 | YTHDF2 | 0.731475 | 3 | 0 | 3 |
| PRPS2 | RPP38 | 0.72962 | 4 | 0 | 3 |
| PRPS2 | FBXW8 | 0.729078 | 3 | 0 | 3 |
| PRPS2 | TTLL4 | 0.729026 | 3 | 0 | 3 |
| PRPS2 | CHAMP1 | 0.721744 | 3 | 0 | 3 |
| PRPS2 | SLITRK6 | 0.707636 | 3 | 0 | 3 |
| PRPS2 | COMMD2 | 0.705422 | 5 | 0 | 4 |
| PRPS2 | CHD7 | 0.703783 | 3 | 0 | 3 |
| PRPS2 | POLE3 | 0.700458 | 6 | 0 | 6 |
| PRPS2 | ZNF664 | 0.697053 | 3 | 0 | 3 |
| PRPS2 | INTS10 | 0.694132 | 5 | 0 | 4 |
| PRPS2 | PPP2R1B | 0.69351 | 4 | 0 | 3 |
For details and further investigation, click here
