| Full name: exportin 7 | Alias Symbol: KIAA0745 | ||
| Type: protein-coding gene | Cytoband: 8p21.3 | ||
| Entrez ID: 23039 | HGNC ID: HGNC:14108 | Ensembl Gene: ENSG00000130227 | OMIM ID: 606140 |
| Drug and gene relationship at DGIdb | |||
Expression of XPO7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | XPO7 | 23039 | 212166_at | 0.5503 | 0.1050 | |
| GSE20347 | XPO7 | 23039 | 212166_at | 0.3019 | 0.0165 | |
| GSE23400 | XPO7 | 23039 | 212166_at | 0.1863 | 0.0005 | |
| GSE26886 | XPO7 | 23039 | 212166_at | -0.5489 | 0.0028 | |
| GSE29001 | XPO7 | 23039 | 212166_at | 0.3370 | 0.1097 | |
| GSE38129 | XPO7 | 23039 | 212166_at | 0.2154 | 0.0379 | |
| GSE45670 | XPO7 | 23039 | 212166_at | 0.3582 | 0.0070 | |
| GSE53622 | XPO7 | 23039 | 20391 | 0.1959 | 0.0075 | |
| GSE53624 | XPO7 | 23039 | 20391 | 0.3244 | 0.0000 | |
| GSE63941 | XPO7 | 23039 | 212166_at | 0.6831 | 0.0955 | |
| GSE77861 | XPO7 | 23039 | 212166_at | 0.2486 | 0.2960 | |
| GSE97050 | XPO7 | 23039 | A_33_P3211473 | 0.0349 | 0.8987 | |
| SRP007169 | XPO7 | 23039 | RNAseq | 1.0740 | 0.0342 | |
| SRP008496 | XPO7 | 23039 | RNAseq | 0.8543 | 0.0077 | |
| SRP064894 | XPO7 | 23039 | RNAseq | 0.1510 | 0.3968 | |
| SRP133303 | XPO7 | 23039 | RNAseq | 0.0129 | 0.9466 | |
| SRP159526 | XPO7 | 23039 | RNAseq | 0.0942 | 0.6835 | |
| SRP193095 | XPO7 | 23039 | RNAseq | 0.0260 | 0.7796 | |
| SRP219564 | XPO7 | 23039 | RNAseq | -0.0084 | 0.9676 | |
| TCGA | XPO7 | 23039 | RNAseq | 0.0306 | 0.5100 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by XPO7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of XPO7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | XPO7 | 23039 | 4 | 10 | 16 | |
| GSE20123 | XPO7 | 23039 | 4 | 10 | 16 | |
| GSE43470 | XPO7 | 23039 | 4 | 9 | 30 | |
| GSE46452 | XPO7 | 23039 | 13 | 13 | 33 | |
| GSE47630 | XPO7 | 23039 | 10 | 8 | 22 | |
| GSE54993 | XPO7 | 23039 | 2 | 14 | 54 | |
| GSE54994 | XPO7 | 23039 | 8 | 18 | 27 | |
| GSE60625 | XPO7 | 23039 | 3 | 0 | 8 | |
| GSE74703 | XPO7 | 23039 | 4 | 7 | 25 | |
| GSE74704 | XPO7 | 23039 | 3 | 7 | 10 | |
| TCGA | XPO7 | 23039 | 13 | 43 | 40 |
Total number of gains: 68; Total number of losses: 139; Total Number of normals: 281.
Somatic mutations of XPO7:
Generating mutation plots.
Highly correlated genes for XPO7:
Showing top 20/499 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| XPO7 | BSDC1 | 0.779259 | 3 | 0 | 3 |
| XPO7 | LRIF1 | 0.770732 | 3 | 0 | 3 |
| XPO7 | SLC7A6 | 0.766472 | 4 | 0 | 4 |
| XPO7 | HEXA | 0.755191 | 4 | 0 | 4 |
| XPO7 | KCTD2 | 0.753272 | 3 | 0 | 3 |
| XPO7 | MED10 | 0.734679 | 3 | 0 | 3 |
| XPO7 | TATDN2 | 0.734041 | 3 | 0 | 3 |
| XPO7 | C5orf51 | 0.731272 | 3 | 0 | 3 |
| XPO7 | GCLC | 0.729735 | 4 | 0 | 3 |
| XPO7 | RPRD1B | 0.726346 | 4 | 0 | 4 |
| XPO7 | NAA25 | 0.720794 | 3 | 0 | 3 |
| XPO7 | CDK6 | 0.720081 | 4 | 0 | 4 |
| XPO7 | TSN | 0.713884 | 4 | 0 | 3 |
| XPO7 | ALG10 | 0.711507 | 3 | 0 | 3 |
| XPO7 | ATP2C2 | 0.708781 | 3 | 0 | 3 |
| XPO7 | CSRNP2 | 0.705852 | 3 | 0 | 3 |
| XPO7 | EGLN2 | 0.705487 | 3 | 0 | 3 |
| XPO7 | NAE1 | 0.700699 | 4 | 0 | 3 |
| XPO7 | KIAA1586 | 0.700555 | 3 | 0 | 3 |
| XPO7 | TPD52L2 | 0.697217 | 3 | 0 | 3 |
For details and further investigation, click here
