| Full name: guided entry of tail-anchored proteins factor 4 | Alias Symbol: CGI-20|H_NH1244M04.5|CEE|TRC35 | ||
| Type: protein-coding gene | Cytoband: 7p22.3 | ||
| Entrez ID: 51608 | HGNC ID: HGNC:21690 | Ensembl Gene: ENSG00000239857 | OMIM ID: 612056 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GET4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GET4 | 51608 | 224808_s_at | 0.0960 | 0.7646 | |
| GSE26886 | GET4 | 51608 | 224808_s_at | -0.2495 | 0.2254 | |
| GSE45670 | GET4 | 51608 | 224808_s_at | 0.0707 | 0.5450 | |
| GSE63941 | GET4 | 51608 | 224808_s_at | 0.6477 | 0.1134 | |
| GSE77861 | GET4 | 51608 | 224808_s_at | 0.0483 | 0.7796 | |
| GSE97050 | GET4 | 51608 | A_24_P400355 | 0.1190 | 0.6387 | |
| SRP007169 | GET4 | 51608 | RNAseq | -0.8017 | 0.0536 | |
| SRP008496 | GET4 | 51608 | RNAseq | -0.5057 | 0.0533 | |
| SRP064894 | GET4 | 51608 | RNAseq | 0.0563 | 0.8317 | |
| SRP133303 | GET4 | 51608 | RNAseq | -0.0862 | 0.5882 | |
| SRP159526 | GET4 | 51608 | RNAseq | -0.2655 | 0.2418 | |
| SRP193095 | GET4 | 51608 | RNAseq | -0.2221 | 0.0568 | |
| SRP219564 | GET4 | 51608 | RNAseq | -0.0192 | 0.9632 | |
| TCGA | GET4 | 51608 | RNAseq | -0.0181 | 0.7261 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GET4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of GET4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GET4 | 51608 | 14 | 0 | 16 | |
| GSE20123 | GET4 | 51608 | 14 | 0 | 16 | |
| GSE43470 | GET4 | 51608 | 6 | 2 | 35 | |
| GSE46452 | GET4 | 51608 | 13 | 1 | 45 | |
| GSE47630 | GET4 | 51608 | 12 | 1 | 27 | |
| GSE54993 | GET4 | 51608 | 3 | 10 | 57 | |
| GSE54994 | GET4 | 51608 | 20 | 3 | 30 | |
| GSE60625 | GET4 | 51608 | 0 | 0 | 11 | |
| GSE74703 | GET4 | 51608 | 6 | 1 | 29 | |
| GSE74704 | GET4 | 51608 | 9 | 0 | 11 | |
| TCGA | GET4 | 51608 | 57 | 5 | 34 |
Total number of gains: 154; Total number of losses: 23; Total Number of normals: 311.
Somatic mutations of GET4:
Generating mutation plots.
Highly correlated genes for GET4:
Showing top 20/139 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GET4 | AGPAT4 | 0.814685 | 3 | 0 | 3 |
| GET4 | RRAGC | 0.761096 | 3 | 0 | 3 |
| GET4 | UBE3B | 0.750098 | 3 | 0 | 3 |
| GET4 | AGTPBP1 | 0.748459 | 3 | 0 | 3 |
| GET4 | ZNF8 | 0.741072 | 3 | 0 | 3 |
| GET4 | DDX54 | 0.739046 | 3 | 0 | 3 |
| GET4 | E4F1 | 0.732365 | 3 | 0 | 3 |
| GET4 | MKKS | 0.729421 | 3 | 0 | 3 |
| GET4 | TRIM62 | 0.722934 | 3 | 0 | 3 |
| GET4 | FNTA | 0.71992 | 3 | 0 | 3 |
| GET4 | CNOT2 | 0.719871 | 3 | 0 | 3 |
| GET4 | PEX10 | 0.719551 | 3 | 0 | 3 |
| GET4 | STX10 | 0.718364 | 3 | 0 | 3 |
| GET4 | BTAF1 | 0.717871 | 3 | 0 | 3 |
| GET4 | TBC1D8 | 0.717855 | 3 | 0 | 3 |
| GET4 | NUDT9 | 0.709544 | 3 | 0 | 3 |
| GET4 | SFSWAP | 0.709467 | 3 | 0 | 3 |
| GET4 | NCOA6 | 0.709398 | 3 | 0 | 3 |
| GET4 | MSL2 | 0.706761 | 3 | 0 | 3 |
| GET4 | SPATA2 | 0.705701 | 3 | 0 | 3 |
For details and further investigation, click here
