| Full name: advillin | Alias Symbol: p92|FLJ12386|ADVIL|DOC6 | ||
| Type: protein-coding gene | Cytoband: 12q14.1 | ||
| Entrez ID: 10677 | HGNC ID: HGNC:14188 | Ensembl Gene: ENSG00000135407 | OMIM ID: 613397 |
| Drug and gene relationship at DGIdb | |||
Expression of AVIL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AVIL | 10677 | 233333_x_at | 0.0136 | 0.9813 | |
| GSE20347 | AVIL | 10677 | 210507_s_at | 0.1493 | 0.0489 | |
| GSE23400 | AVIL | 10677 | 205539_at | 0.0361 | 0.3754 | |
| GSE26886 | AVIL | 10677 | 233333_x_at | -0.0646 | 0.6574 | |
| GSE29001 | AVIL | 10677 | 205539_at | 0.0123 | 0.9642 | |
| GSE38129 | AVIL | 10677 | 210507_s_at | 0.0905 | 0.2245 | |
| GSE45670 | AVIL | 10677 | 233333_x_at | 0.3202 | 0.0011 | |
| GSE53622 | AVIL | 10677 | 46649 | 0.8164 | 0.0000 | |
| GSE53624 | AVIL | 10677 | 46649 | 0.5289 | 0.0000 | |
| GSE63941 | AVIL | 10677 | 233333_x_at | 0.1176 | 0.5863 | |
| GSE77861 | AVIL | 10677 | 233333_x_at | 0.0727 | 0.7363 | |
| GSE97050 | AVIL | 10677 | A_24_P419087 | 0.1506 | 0.4620 | |
| SRP007169 | AVIL | 10677 | RNAseq | 1.2474 | 0.1929 | |
| SRP064894 | AVIL | 10677 | RNAseq | 0.9217 | 0.0003 | |
| SRP133303 | AVIL | 10677 | RNAseq | 0.3228 | 0.0349 | |
| SRP193095 | AVIL | 10677 | RNAseq | 0.6662 | 0.0003 | |
| SRP219564 | AVIL | 10677 | RNAseq | 0.2231 | 0.6456 | |
| TCGA | AVIL | 10677 | RNAseq | -0.2702 | 0.1941 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AVIL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AVIL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AVIL | 10677 | 7 | 1 | 22 | |
| GSE20123 | AVIL | 10677 | 7 | 0 | 23 | |
| GSE43470 | AVIL | 10677 | 2 | 0 | 41 | |
| GSE46452 | AVIL | 10677 | 8 | 1 | 50 | |
| GSE47630 | AVIL | 10677 | 10 | 2 | 28 | |
| GSE54993 | AVIL | 10677 | 0 | 5 | 65 | |
| GSE54994 | AVIL | 10677 | 4 | 1 | 48 | |
| GSE60625 | AVIL | 10677 | 0 | 0 | 11 | |
| GSE74703 | AVIL | 10677 | 2 | 0 | 34 | |
| GSE74704 | AVIL | 10677 | 5 | 0 | 15 | |
| TCGA | AVIL | 10677 | 15 | 10 | 71 |
Total number of gains: 60; Total number of losses: 20; Total Number of normals: 408.
Somatic mutations of AVIL:
Generating mutation plots.
Highly correlated genes for AVIL:
Showing top 20/136 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AVIL | SAMD4B | 0.775252 | 3 | 0 | 3 |
| AVIL | OCIAD1 | 0.769946 | 3 | 0 | 3 |
| AVIL | C9orf64 | 0.755232 | 5 | 0 | 5 |
| AVIL | DDX59 | 0.746892 | 5 | 0 | 5 |
| AVIL | ZNF417 | 0.745983 | 3 | 0 | 3 |
| AVIL | ANKHD1 | 0.744186 | 3 | 0 | 3 |
| AVIL | UBE2V2 | 0.740349 | 3 | 0 | 3 |
| AVIL | NKTR | 0.738326 | 3 | 0 | 3 |
| AVIL | PROK2 | 0.727057 | 3 | 0 | 3 |
| AVIL | FAM161B | 0.695551 | 5 | 0 | 3 |
| AVIL | ALKBH6 | 0.692961 | 3 | 0 | 3 |
| AVIL | ADH4 | 0.691464 | 4 | 0 | 4 |
| AVIL | TAF3 | 0.688712 | 3 | 0 | 3 |
| AVIL | ANKRD10 | 0.688099 | 3 | 0 | 3 |
| AVIL | SPIRE2 | 0.68762 | 3 | 0 | 3 |
| AVIL | AKT2 | 0.68566 | 4 | 0 | 3 |
| AVIL | CIC | 0.684974 | 4 | 0 | 3 |
| AVIL | CMBL | 0.683715 | 4 | 0 | 4 |
| AVIL | AKAP17A | 0.682619 | 3 | 0 | 3 |
| AVIL | THOC2 | 0.681903 | 4 | 0 | 3 |
For details and further investigation, click here
