| Full name: TATA-box binding protein associated factor 3 | Alias Symbol: TAF140|TAFII140 | ||
| Type: protein-coding gene | Cytoband: 10p14 | ||
| Entrez ID: 83860 | HGNC ID: HGNC:17303 | Ensembl Gene: ENSG00000165632 | OMIM ID: 606576 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TAF3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAF3 | 83860 | 235154_at | 0.1869 | 0.7709 | |
| GSE26886 | TAF3 | 83860 | 235119_at | 0.2937 | 0.2065 | |
| GSE45670 | TAF3 | 83860 | 235154_at | 0.2514 | 0.0533 | |
| GSE53622 | TAF3 | 83860 | 147545 | 0.0660 | 0.3459 | |
| GSE53624 | TAF3 | 83860 | 147545 | 0.2700 | 0.0001 | |
| GSE63941 | TAF3 | 83860 | 235119_at | -0.1591 | 0.7449 | |
| GSE77861 | TAF3 | 83860 | 235154_at | -0.0360 | 0.7926 | |
| GSE97050 | TAF3 | 83860 | A_32_P153892 | -0.1297 | 0.5890 | |
| SRP007169 | TAF3 | 83860 | RNAseq | 2.1965 | 0.0017 | |
| SRP064894 | TAF3 | 83860 | RNAseq | 0.6327 | 0.0031 | |
| SRP133303 | TAF3 | 83860 | RNAseq | 0.1445 | 0.2416 | |
| SRP159526 | TAF3 | 83860 | RNAseq | 0.0474 | 0.8873 | |
| SRP193095 | TAF3 | 83860 | RNAseq | 0.1931 | 0.0830 | |
| SRP219564 | TAF3 | 83860 | RNAseq | 0.3451 | 0.3103 | |
| TCGA | TAF3 | 83860 | RNAseq | -0.0775 | 0.2269 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TAF3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAF3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAF3 | 83860 | 4 | 8 | 18 | |
| GSE20123 | TAF3 | 83860 | 4 | 7 | 19 | |
| GSE43470 | TAF3 | 83860 | 3 | 6 | 34 | |
| GSE46452 | TAF3 | 83860 | 2 | 14 | 43 | |
| GSE47630 | TAF3 | 83860 | 5 | 15 | 20 | |
| GSE54993 | TAF3 | 83860 | 11 | 0 | 59 | |
| GSE54994 | TAF3 | 83860 | 4 | 10 | 39 | |
| GSE60625 | TAF3 | 83860 | 0 | 0 | 11 | |
| GSE74703 | TAF3 | 83860 | 2 | 4 | 30 | |
| GSE74704 | TAF3 | 83860 | 1 | 6 | 13 | |
| TCGA | TAF3 | 83860 | 19 | 26 | 51 |
Total number of gains: 55; Total number of losses: 96; Total Number of normals: 337.
Somatic mutations of TAF3:
Generating mutation plots.
Highly correlated genes for TAF3:
Showing top 20/84 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAF3 | BRD2 | 0.827526 | 3 | 0 | 3 |
| TAF3 | U2AF2 | 0.777733 | 3 | 0 | 3 |
| TAF3 | ZNF609 | 0.743369 | 3 | 0 | 3 |
| TAF3 | DDX59 | 0.738677 | 3 | 0 | 3 |
| TAF3 | SYMPK | 0.725551 | 3 | 0 | 3 |
| TAF3 | VPS72 | 0.720887 | 3 | 0 | 3 |
| TAF3 | TIGD1 | 0.71967 | 3 | 0 | 3 |
| TAF3 | RPRD2 | 0.71431 | 3 | 0 | 3 |
| TAF3 | CCDC144A | 0.712292 | 3 | 0 | 3 |
| TAF3 | ZNF417 | 0.705627 | 3 | 0 | 3 |
| TAF3 | FUBP1 | 0.696172 | 3 | 0 | 3 |
| TAF3 | AVIL | 0.688712 | 3 | 0 | 3 |
| TAF3 | RBM38 | 0.683133 | 3 | 0 | 3 |
| TAF3 | SRSF1 | 0.682743 | 3 | 0 | 3 |
| TAF3 | PPP1R37 | 0.679292 | 3 | 0 | 3 |
| TAF3 | ANO6 | 0.675739 | 3 | 0 | 3 |
| TAF3 | CLMP | 0.674649 | 3 | 0 | 3 |
| TAF3 | ZNF445 | 0.672594 | 3 | 0 | 3 |
| TAF3 | ATF7IP | 0.66986 | 3 | 0 | 3 |
| TAF3 | ANKRD17 | 0.663366 | 4 | 0 | 3 |
For details and further investigation, click here
