| Full name: extracellular matrix protein 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q21.2 | ||
| Entrez ID: 1893 | HGNC ID: HGNC:3153 | Ensembl Gene: ENSG00000143369 | OMIM ID: 602201 |
| Drug and gene relationship at DGIdb | |||
Expression of ECM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ECM1 | 1893 | 209365_s_at | -3.2616 | 0.0336 | |
| GSE20347 | ECM1 | 1893 | 209365_s_at | -3.6635 | 0.0000 | |
| GSE23400 | ECM1 | 1893 | 209365_s_at | -2.9938 | 0.0000 | |
| GSE26886 | ECM1 | 1893 | 209365_s_at | -4.4876 | 0.0000 | |
| GSE29001 | ECM1 | 1893 | 209365_s_at | -3.7111 | 0.0000 | |
| GSE38129 | ECM1 | 1893 | 209365_s_at | -2.9478 | 0.0000 | |
| GSE45670 | ECM1 | 1893 | 209365_s_at | -1.5656 | 0.0175 | |
| GSE53622 | ECM1 | 1893 | 3984 | -3.3739 | 0.0000 | |
| GSE53624 | ECM1 | 1893 | 3984 | -3.7238 | 0.0000 | |
| GSE63941 | ECM1 | 1893 | 209365_s_at | -2.3107 | 0.0053 | |
| GSE77861 | ECM1 | 1893 | 209365_s_at | -2.4158 | 0.0007 | |
| GSE97050 | ECM1 | 1893 | A_23_P160559 | -2.5750 | 0.1260 | |
| SRP007169 | ECM1 | 1893 | RNAseq | -6.1304 | 0.0000 | |
| SRP008496 | ECM1 | 1893 | RNAseq | -6.2177 | 0.0000 | |
| SRP064894 | ECM1 | 1893 | RNAseq | -4.4951 | 0.0000 | |
| SRP133303 | ECM1 | 1893 | RNAseq | -4.3854 | 0.0000 | |
| SRP159526 | ECM1 | 1893 | RNAseq | -5.5589 | 0.0000 | |
| SRP193095 | ECM1 | 1893 | RNAseq | -4.4855 | 0.0000 | |
| SRP219564 | ECM1 | 1893 | RNAseq | -4.1162 | 0.0000 | |
| TCGA | ECM1 | 1893 | RNAseq | 0.1255 | 0.3963 |
Upregulated datasets: 0; Downregulated datasets: 18.
Survival by ECM1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ECM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ECM1 | 1893 | 15 | 0 | 15 | |
| GSE20123 | ECM1 | 1893 | 15 | 0 | 15 | |
| GSE43470 | ECM1 | 1893 | 6 | 1 | 36 | |
| GSE46452 | ECM1 | 1893 | 2 | 1 | 56 | |
| GSE47630 | ECM1 | 1893 | 14 | 0 | 26 | |
| GSE54993 | ECM1 | 1893 | 0 | 3 | 67 | |
| GSE54994 | ECM1 | 1893 | 15 | 0 | 38 | |
| GSE60625 | ECM1 | 1893 | 0 | 0 | 11 | |
| GSE74703 | ECM1 | 1893 | 6 | 1 | 29 | |
| GSE74704 | ECM1 | 1893 | 7 | 0 | 13 | |
| TCGA | ECM1 | 1893 | 38 | 2 | 56 |
Total number of gains: 118; Total number of losses: 8; Total Number of normals: 362.
Somatic mutations of ECM1:
Generating mutation plots.
Highly correlated genes for ECM1:
Showing top 20/1343 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ECM1 | CYSRT1 | 0.956553 | 6 | 0 | 6 |
| ECM1 | EMP1 | 0.907472 | 11 | 0 | 11 |
| ECM1 | VSIG10L | 0.902777 | 7 | 0 | 7 |
| ECM1 | CRISP3 | 0.901776 | 11 | 0 | 11 |
| ECM1 | KRT78 | 0.896807 | 8 | 0 | 8 |
| ECM1 | GYS2 | 0.89284 | 10 | 0 | 10 |
| ECM1 | CRCT1 | 0.887846 | 12 | 0 | 12 |
| ECM1 | SLURP1 | 0.885993 | 12 | 0 | 12 |
| ECM1 | GDPD3 | 0.884824 | 12 | 0 | 12 |
| ECM1 | CLIC3 | 0.883986 | 10 | 0 | 10 |
| ECM1 | CXCR2 | 0.882738 | 10 | 0 | 10 |
| ECM1 | IL36A | 0.881763 | 11 | 0 | 11 |
| ECM1 | MXD1 | 0.881666 | 12 | 0 | 11 |
| ECM1 | FLG | 0.878582 | 11 | 0 | 11 |
| ECM1 | RHCG | 0.876534 | 12 | 0 | 12 |
| ECM1 | TMOD3 | 0.876381 | 11 | 0 | 11 |
| ECM1 | CRNN | 0.875954 | 12 | 0 | 12 |
| ECM1 | SPINK7 | 0.874276 | 8 | 0 | 7 |
| ECM1 | UPK1A | 0.873499 | 11 | 0 | 11 |
| ECM1 | FCHO2 | 0.873068 | 6 | 0 | 6 |
For details and further investigation, click here
