| Full name: carcinoembryonic antigen related cell adhesion molecule 5 | Alias Symbol: CD66e | ||
| Type: protein-coding gene | Cytoband: 19q13.2 | ||
| Entrez ID: 1048 | HGNC ID: HGNC:1817 | Ensembl Gene: ENSG00000105388 | OMIM ID: 114890 |
| Drug and gene relationship at DGIdb | |||
Expression of CEACAM5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CEACAM5 | 1048 | 201884_at | -3.5944 | 0.0733 | |
| GSE20347 | CEACAM5 | 1048 | 201884_at | -3.8425 | 0.0000 | |
| GSE23400 | CEACAM5 | 1048 | 201884_at | -2.4470 | 0.0000 | |
| GSE26886 | CEACAM5 | 1048 | 201884_at | -6.6586 | 0.0000 | |
| GSE29001 | CEACAM5 | 1048 | 201884_at | -4.0701 | 0.0001 | |
| GSE38129 | CEACAM5 | 1048 | 201884_at | -2.6428 | 0.0001 | |
| GSE45670 | CEACAM5 | 1048 | 201884_at | -0.8453 | 0.1518 | |
| GSE53622 | CEACAM5 | 1048 | 117819 | -2.5706 | 0.0000 | |
| GSE53624 | CEACAM5 | 1048 | 117819 | -2.9066 | 0.0000 | |
| GSE63941 | CEACAM5 | 1048 | 201884_at | 2.0249 | 0.3645 | |
| GSE77861 | CEACAM5 | 1048 | 201884_at | -2.2239 | 0.0577 | |
| GSE97050 | CEACAM5 | 1048 | A_23_P153301 | -0.8002 | 0.2733 | |
| SRP007169 | CEACAM5 | 1048 | RNAseq | -2.2659 | 0.2357 | |
| SRP008496 | CEACAM5 | 1048 | RNAseq | -3.7494 | 0.0008 | |
| SRP064894 | CEACAM5 | 1048 | RNAseq | -3.3782 | 0.0000 | |
| SRP133303 | CEACAM5 | 1048 | RNAseq | -2.4563 | 0.0000 | |
| SRP159526 | CEACAM5 | 1048 | RNAseq | -3.7948 | 0.0003 | |
| SRP193095 | CEACAM5 | 1048 | RNAseq | -1.6731 | 0.0016 | |
| SRP219564 | CEACAM5 | 1048 | RNAseq | -4.1796 | 0.0005 | |
| TCGA | CEACAM5 | 1048 | RNAseq | -0.3111 | 0.3799 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by CEACAM5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CEACAM5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CEACAM5 | 1048 | 4 | 4 | 22 | |
| GSE20123 | CEACAM5 | 1048 | 4 | 3 | 23 | |
| GSE43470 | CEACAM5 | 1048 | 3 | 11 | 29 | |
| GSE46452 | CEACAM5 | 1048 | 48 | 1 | 10 | |
| GSE47630 | CEACAM5 | 1048 | 9 | 5 | 26 | |
| GSE54993 | CEACAM5 | 1048 | 17 | 4 | 49 | |
| GSE54994 | CEACAM5 | 1048 | 7 | 12 | 34 | |
| GSE60625 | CEACAM5 | 1048 | 9 | 0 | 2 | |
| GSE74703 | CEACAM5 | 1048 | 3 | 7 | 26 | |
| GSE74704 | CEACAM5 | 1048 | 4 | 1 | 15 | |
| TCGA | CEACAM5 | 1048 | 14 | 16 | 66 |
Total number of gains: 122; Total number of losses: 64; Total Number of normals: 302.
Somatic mutations of CEACAM5:
Generating mutation plots.
Highly correlated genes for CEACAM5:
Showing top 20/1160 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CEACAM5 | CEACAM6 | 0.917994 | 13 | 0 | 13 |
| CEACAM5 | CEACAM7 | 0.866159 | 13 | 0 | 13 |
| CEACAM5 | CEACAM1 | 0.862827 | 12 | 0 | 12 |
| CEACAM5 | OTOP3 | 0.857727 | 3 | 0 | 3 |
| CEACAM5 | CAPN14 | 0.85545 | 7 | 0 | 7 |
| CEACAM5 | TPRG1 | 0.847365 | 6 | 0 | 6 |
| CEACAM5 | SCEL | 0.84653 | 13 | 0 | 12 |
| CEACAM5 | ECM1 | 0.843646 | 11 | 0 | 11 |
| CEACAM5 | TMPRSS11B | 0.841099 | 8 | 0 | 8 |
| CEACAM5 | VSIG10L | 0.838203 | 7 | 0 | 7 |
| CEACAM5 | EVPL | 0.833476 | 11 | 0 | 11 |
| CEACAM5 | FUT3 | 0.83324 | 13 | 0 | 13 |
| CEACAM5 | SLURP1 | 0.83218 | 12 | 0 | 11 |
| CEACAM5 | CLCA4 | 0.832013 | 13 | 0 | 12 |
| CEACAM5 | CRNN | 0.831775 | 12 | 0 | 12 |
| CEACAM5 | FAM3D | 0.830556 | 9 | 0 | 9 |
| CEACAM5 | CYP2C8 | 0.829056 | 3 | 0 | 3 |
| CEACAM5 | CES2 | 0.828325 | 9 | 0 | 9 |
| CEACAM5 | SCNN1B | 0.826896 | 12 | 0 | 12 |
| CEACAM5 | TMEM154 | 0.824944 | 7 | 0 | 7 |
For details and further investigation, click here
