| Full name: mitochondrial ribosomal protein L2 | Alias Symbol: MRP-L14|RPML14|CGI-22 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 51069 | HGNC ID: HGNC:14056 | Ensembl Gene: ENSG00000112651 | OMIM ID: 611822 |
| Drug and gene relationship at DGIdb | |||
Expression of MRPL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRPL2 | 51069 | 229884_s_at | 0.0733 | 0.9381 | |
| GSE20347 | MRPL2 | 51069 | 218887_at | 0.3227 | 0.0209 | |
| GSE23400 | MRPL2 | 51069 | 218887_at | 0.2768 | 0.0001 | |
| GSE26886 | MRPL2 | 51069 | 218887_at | 0.3579 | 0.0280 | |
| GSE29001 | MRPL2 | 51069 | 218887_at | 0.0112 | 0.9617 | |
| GSE38129 | MRPL2 | 51069 | 218887_at | 0.3339 | 0.0010 | |
| GSE45670 | MRPL2 | 51069 | 218887_at | 0.2525 | 0.0100 | |
| GSE53622 | MRPL2 | 51069 | 15062 | 0.3105 | 0.0026 | |
| GSE53624 | MRPL2 | 51069 | 15062 | 0.8751 | 0.0000 | |
| GSE63941 | MRPL2 | 51069 | 229884_s_at | 0.7031 | 0.1274 | |
| GSE77861 | MRPL2 | 51069 | 218887_at | 0.0785 | 0.6910 | |
| GSE97050 | MRPL2 | 51069 | A_23_P7941 | 0.3138 | 0.3645 | |
| SRP007169 | MRPL2 | 51069 | RNAseq | 0.2632 | 0.4786 | |
| SRP008496 | MRPL2 | 51069 | RNAseq | 0.1207 | 0.6672 | |
| SRP064894 | MRPL2 | 51069 | RNAseq | 0.6430 | 0.0122 | |
| SRP133303 | MRPL2 | 51069 | RNAseq | 0.3192 | 0.0104 | |
| SRP159526 | MRPL2 | 51069 | RNAseq | 0.5569 | 0.0001 | |
| SRP193095 | MRPL2 | 51069 | RNAseq | 0.3065 | 0.0220 | |
| SRP219564 | MRPL2 | 51069 | RNAseq | 0.6562 | 0.1090 | |
| TCGA | MRPL2 | 51069 | RNAseq | 0.1827 | 0.0067 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRPL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRPL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRPL2 | 51069 | 7 | 0 | 23 | |
| GSE20123 | MRPL2 | 51069 | 7 | 0 | 23 | |
| GSE43470 | MRPL2 | 51069 | 6 | 0 | 37 | |
| GSE46452 | MRPL2 | 51069 | 2 | 9 | 48 | |
| GSE47630 | MRPL2 | 51069 | 8 | 4 | 28 | |
| GSE54993 | MRPL2 | 51069 | 3 | 2 | 65 | |
| GSE54994 | MRPL2 | 51069 | 11 | 4 | 38 | |
| GSE60625 | MRPL2 | 51069 | 0 | 1 | 10 | |
| GSE74703 | MRPL2 | 51069 | 6 | 0 | 30 | |
| GSE74704 | MRPL2 | 51069 | 3 | 0 | 17 | |
| TCGA | MRPL2 | 51069 | 21 | 13 | 62 |
Total number of gains: 74; Total number of losses: 33; Total Number of normals: 381.
Somatic mutations of MRPL2:
Generating mutation plots.
Highly correlated genes for MRPL2:
Showing top 20/555 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRPL2 | ZNF256 | 0.780149 | 3 | 0 | 3 |
| MRPL2 | KTI12 | 0.76939 | 3 | 0 | 3 |
| MRPL2 | ADNP2 | 0.75233 | 3 | 0 | 3 |
| MRPL2 | IPO11 | 0.751767 | 3 | 0 | 3 |
| MRPL2 | ZNF707 | 0.732846 | 3 | 0 | 3 |
| MRPL2 | BAG1 | 0.720665 | 3 | 0 | 3 |
| MRPL2 | GZF1 | 0.709283 | 3 | 0 | 3 |
| MRPL2 | CHCHD3 | 0.70845 | 3 | 0 | 3 |
| MRPL2 | ZNF628 | 0.708203 | 5 | 0 | 5 |
| MRPL2 | BRAT1 | 0.705236 | 3 | 0 | 3 |
| MRPL2 | DUSP23 | 0.699297 | 3 | 0 | 3 |
| MRPL2 | GABPB1 | 0.698327 | 3 | 0 | 3 |
| MRPL2 | TBRG4 | 0.689032 | 4 | 0 | 3 |
| MRPL2 | ZNF502 | 0.683931 | 3 | 0 | 3 |
| MRPL2 | B3GALNT2 | 0.681997 | 3 | 0 | 3 |
| MRPL2 | FKBP10 | 0.67761 | 3 | 0 | 3 |
| MRPL2 | AHCTF1 | 0.67663 | 4 | 0 | 3 |
| MRPL2 | FMNL2 | 0.67507 | 3 | 0 | 3 |
| MRPL2 | TP53I13 | 0.674203 | 3 | 0 | 3 |
| MRPL2 | AGK | 0.666234 | 3 | 0 | 3 |
For details and further investigation, click here
