| Full name: DnaJ heat shock protein family (Hsp40) member C24 | Alias Symbol: JJJ3 | ||
| Type: protein-coding gene | Cytoband: 11p13 | ||
| Entrez ID: 120526 | HGNC ID: HGNC:26979 | Ensembl Gene: ENSG00000170946 | OMIM ID: 611072 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAJC24:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJC24 | 120526 | 213853_at | -0.2729 | 0.4692 | |
| GSE20347 | DNAJC24 | 120526 | 213853_at | -0.5233 | 0.0001 | |
| GSE23400 | DNAJC24 | 120526 | 213853_at | 0.0881 | 0.0926 | |
| GSE26886 | DNAJC24 | 120526 | 213853_at | 0.6905 | 0.0048 | |
| GSE29001 | DNAJC24 | 120526 | 213853_at | 0.1281 | 0.6738 | |
| GSE38129 | DNAJC24 | 120526 | 213853_at | -0.5190 | 0.0001 | |
| GSE45670 | DNAJC24 | 120526 | 213853_at | -0.2706 | 0.1316 | |
| GSE63941 | DNAJC24 | 120526 | 213853_at | -0.4865 | 0.2753 | |
| GSE77861 | DNAJC24 | 120526 | 213853_at | 0.1487 | 0.5331 | |
| GSE97050 | DNAJC24 | 120526 | A_32_P198303 | -0.0642 | 0.8287 | |
| SRP007169 | DNAJC24 | 120526 | RNAseq | 1.0197 | 0.0235 | |
| SRP008496 | DNAJC24 | 120526 | RNAseq | 1.6176 | 0.0001 | |
| SRP064894 | DNAJC24 | 120526 | RNAseq | 0.2099 | 0.1302 | |
| SRP133303 | DNAJC24 | 120526 | RNAseq | 0.2746 | 0.0466 | |
| SRP159526 | DNAJC24 | 120526 | RNAseq | -0.3760 | 0.0573 | |
| SRP193095 | DNAJC24 | 120526 | RNAseq | -0.1256 | 0.0681 | |
| SRP219564 | DNAJC24 | 120526 | RNAseq | -0.1482 | 0.6308 | |
| TCGA | DNAJC24 | 120526 | RNAseq | -0.1260 | 0.0543 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by DNAJC24 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of DNAJC24:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJC24 | 120526 | 1 | 9 | 20 | |
| GSE20123 | DNAJC24 | 120526 | 1 | 8 | 21 | |
| GSE43470 | DNAJC24 | 120526 | 2 | 4 | 37 | |
| GSE46452 | DNAJC24 | 120526 | 8 | 5 | 46 | |
| GSE47630 | DNAJC24 | 120526 | 3 | 10 | 27 | |
| GSE54993 | DNAJC24 | 120526 | 3 | 0 | 67 | |
| GSE54994 | DNAJC24 | 120526 | 4 | 10 | 39 | |
| GSE60625 | DNAJC24 | 120526 | 0 | 0 | 11 | |
| GSE74703 | DNAJC24 | 120526 | 2 | 2 | 32 | |
| GSE74704 | DNAJC24 | 120526 | 0 | 7 | 13 | |
| TCGA | DNAJC24 | 120526 | 12 | 24 | 60 |
Total number of gains: 36; Total number of losses: 79; Total Number of normals: 373.
Somatic mutations of DNAJC24:
Generating mutation plots.
Highly correlated genes for DNAJC24:
Showing top 20/363 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJC24 | ZBTB8A | 0.87081 | 3 | 0 | 3 |
| DNAJC24 | SMAD5 | 0.780275 | 3 | 0 | 3 |
| DNAJC24 | GPBP1 | 0.774581 | 3 | 0 | 3 |
| DNAJC24 | PANX1 | 0.766982 | 3 | 0 | 3 |
| DNAJC24 | DCAF10 | 0.756932 | 3 | 0 | 3 |
| DNAJC24 | PPP1R15B | 0.755455 | 3 | 0 | 3 |
| DNAJC24 | NHS | 0.739548 | 3 | 0 | 3 |
| DNAJC24 | RHOBTB3 | 0.737279 | 3 | 0 | 3 |
| DNAJC24 | UBQLN1 | 0.732904 | 3 | 0 | 3 |
| DNAJC24 | TWISTNB | 0.730745 | 3 | 0 | 3 |
| DNAJC24 | TRMT6 | 0.716683 | 3 | 0 | 3 |
| DNAJC24 | PTPN23 | 0.716658 | 3 | 0 | 3 |
| DNAJC24 | BAG1 | 0.714986 | 3 | 0 | 3 |
| DNAJC24 | ZNF141 | 0.705672 | 4 | 0 | 3 |
| DNAJC24 | PDHB | 0.703173 | 4 | 0 | 4 |
| DNAJC24 | CLIP1 | 0.701443 | 3 | 0 | 3 |
| DNAJC24 | RNASEH2C | 0.700939 | 3 | 0 | 3 |
| DNAJC24 | FNIP2 | 0.698267 | 4 | 0 | 4 |
| DNAJC24 | ZFX | 0.694636 | 3 | 0 | 3 |
| DNAJC24 | CRBN | 0.693743 | 4 | 0 | 4 |
For details and further investigation, click here
