| Full name: BCL2 associated athanogene 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q32.33 | ||
| Entrez ID: 9529 | HGNC ID: HGNC:941 | Ensembl Gene: ENSG00000166170 | OMIM ID: 603885 |
| Drug and gene relationship at DGIdb | |||
Expression of BAG5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BAG5 | 9529 | 202985_s_at | -0.1267 | 0.7079 | |
| GSE20347 | BAG5 | 9529 | 202985_s_at | -0.2245 | 0.1506 | |
| GSE23400 | BAG5 | 9529 | 202985_s_at | 0.2117 | 0.0091 | |
| GSE26886 | BAG5 | 9529 | 202985_s_at | -0.4301 | 0.0735 | |
| GSE29001 | BAG5 | 9529 | 202985_s_at | 0.1167 | 0.6573 | |
| GSE38129 | BAG5 | 9529 | 202985_s_at | 0.0212 | 0.8841 | |
| GSE45670 | BAG5 | 9529 | 202985_s_at | 0.0057 | 0.9728 | |
| GSE53622 | BAG5 | 9529 | 145057 | -0.2924 | 0.0002 | |
| GSE53624 | BAG5 | 9529 | 145057 | -0.0738 | 0.4766 | |
| GSE63941 | BAG5 | 9529 | 202985_s_at | 0.1443 | 0.7087 | |
| GSE77861 | BAG5 | 9529 | 202985_s_at | 0.1254 | 0.7519 | |
| GSE97050 | BAG5 | 9529 | A_24_P130026 | -0.1903 | 0.5589 | |
| SRP007169 | BAG5 | 9529 | RNAseq | 0.4094 | 0.2161 | |
| SRP008496 | BAG5 | 9529 | RNAseq | 0.4986 | 0.0215 | |
| SRP064894 | BAG5 | 9529 | RNAseq | -0.2251 | 0.1595 | |
| SRP133303 | BAG5 | 9529 | RNAseq | 0.0688 | 0.4537 | |
| SRP159526 | BAG5 | 9529 | RNAseq | -0.0381 | 0.9004 | |
| SRP193095 | BAG5 | 9529 | RNAseq | -0.1515 | 0.1857 | |
| SRP219564 | BAG5 | 9529 | RNAseq | 0.1578 | 0.6918 | |
| TCGA | BAG5 | 9529 | RNAseq | -0.0207 | 0.6610 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by BAG5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BAG5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BAG5 | 9529 | 12 | 3 | 15 | |
| GSE20123 | BAG5 | 9529 | 11 | 2 | 17 | |
| GSE43470 | BAG5 | 9529 | 6 | 4 | 33 | |
| GSE46452 | BAG5 | 9529 | 18 | 4 | 37 | |
| GSE47630 | BAG5 | 9529 | 10 | 8 | 22 | |
| GSE54993 | BAG5 | 9529 | 3 | 8 | 59 | |
| GSE54994 | BAG5 | 9529 | 21 | 4 | 28 | |
| GSE60625 | BAG5 | 9529 | 0 | 2 | 9 | |
| GSE74703 | BAG5 | 9529 | 5 | 3 | 28 | |
| GSE74704 | BAG5 | 9529 | 5 | 2 | 13 | |
| TCGA | BAG5 | 9529 | 31 | 20 | 45 |
Total number of gains: 122; Total number of losses: 60; Total Number of normals: 306.
Somatic mutations of BAG5:
Generating mutation plots.
Highly correlated genes for BAG5:
Showing top 20/277 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BAG5 | SUGT1 | 0.753421 | 3 | 0 | 3 |
| BAG5 | FOXN3 | 0.751023 | 3 | 0 | 3 |
| BAG5 | ANGPTL4 | 0.743496 | 3 | 0 | 3 |
| BAG5 | NMNAT1 | 0.740729 | 3 | 0 | 3 |
| BAG5 | ANKZF1 | 0.739435 | 3 | 0 | 3 |
| BAG5 | HTATSF1 | 0.735983 | 3 | 0 | 3 |
| BAG5 | SNX12 | 0.730898 | 3 | 0 | 3 |
| BAG5 | THAP2 | 0.727975 | 3 | 0 | 3 |
| BAG5 | ZBTB8OS | 0.725921 | 3 | 0 | 3 |
| BAG5 | GLRX2 | 0.723379 | 3 | 0 | 3 |
| BAG5 | TMEM161B | 0.718887 | 3 | 0 | 3 |
| BAG5 | RANBP6 | 0.712846 | 4 | 0 | 3 |
| BAG5 | WDR77 | 0.706801 | 3 | 0 | 3 |
| BAG5 | ACY1 | 0.702388 | 3 | 0 | 3 |
| BAG5 | PIGV | 0.701053 | 3 | 0 | 3 |
| BAG5 | SNX14 | 0.699824 | 3 | 0 | 3 |
| BAG5 | SAP30L | 0.697685 | 3 | 0 | 3 |
| BAG5 | C11orf54 | 0.691107 | 4 | 0 | 3 |
| BAG5 | THUMPD3 | 0.691002 | 5 | 0 | 4 |
| BAG5 | PIP4K2C | 0.690943 | 3 | 0 | 3 |
For details and further investigation, click here
