| Full name: zinc finger and BTB domain containing 8 opposite strand | Alias Symbol: ARCH | ||
| Type: protein-coding gene | Cytoband: 1p35.1 | ||
| Entrez ID: 339487 | HGNC ID: HGNC:24094 | Ensembl Gene: ENSG00000176261 | OMIM ID: 615891 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZBTB8OS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB8OS | 339487 | 228970_at | -0.1425 | 0.6545 | |
| GSE26886 | ZBTB8OS | 339487 | 228970_at | 0.4815 | 0.0129 | |
| GSE45670 | ZBTB8OS | 339487 | 228970_at | 0.3514 | 0.0171 | |
| GSE53622 | ZBTB8OS | 339487 | 76256 | 0.1676 | 0.0072 | |
| GSE53624 | ZBTB8OS | 339487 | 76256 | 0.2459 | 0.0007 | |
| GSE63941 | ZBTB8OS | 339487 | 228970_at | 0.1139 | 0.7881 | |
| GSE77861 | ZBTB8OS | 339487 | 228970_at | -0.0457 | 0.8883 | |
| GSE97050 | ZBTB8OS | 339487 | A_33_P3519683 | 0.2346 | 0.4285 | |
| SRP007169 | ZBTB8OS | 339487 | RNAseq | -0.2739 | 0.5215 | |
| SRP008496 | ZBTB8OS | 339487 | RNAseq | -0.3095 | 0.2044 | |
| SRP064894 | ZBTB8OS | 339487 | RNAseq | 0.2214 | 0.3368 | |
| SRP133303 | ZBTB8OS | 339487 | RNAseq | 0.4436 | 0.0110 | |
| SRP159526 | ZBTB8OS | 339487 | RNAseq | 0.1654 | 0.3240 | |
| SRP193095 | ZBTB8OS | 339487 | RNAseq | -0.2874 | 0.0070 | |
| SRP219564 | ZBTB8OS | 339487 | RNAseq | -0.3281 | 0.2622 | |
| TCGA | ZBTB8OS | 339487 | RNAseq | 0.1179 | 0.0922 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZBTB8OS expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB8OS:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB8OS | 339487 | 2 | 5 | 23 | |
| GSE20123 | ZBTB8OS | 339487 | 2 | 4 | 24 | |
| GSE43470 | ZBTB8OS | 339487 | 4 | 6 | 33 | |
| GSE46452 | ZBTB8OS | 339487 | 5 | 1 | 53 | |
| GSE47630 | ZBTB8OS | 339487 | 8 | 3 | 29 | |
| GSE54993 | ZBTB8OS | 339487 | 1 | 1 | 68 | |
| GSE54994 | ZBTB8OS | 339487 | 11 | 2 | 40 | |
| GSE60625 | ZBTB8OS | 339487 | 0 | 0 | 11 | |
| GSE74703 | ZBTB8OS | 339487 | 3 | 3 | 30 | |
| GSE74704 | ZBTB8OS | 339487 | 1 | 0 | 19 | |
| TCGA | ZBTB8OS | 339487 | 12 | 19 | 65 |
Total number of gains: 49; Total number of losses: 44; Total Number of normals: 395.
Somatic mutations of ZBTB8OS:
Generating mutation plots.
Highly correlated genes for ZBTB8OS:
Showing top 20/359 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB8OS | HSPA9 | 0.789368 | 3 | 0 | 3 |
| ZBTB8OS | SPTLC2 | 0.7798 | 3 | 0 | 3 |
| ZBTB8OS | DNAJC2 | 0.774818 | 3 | 0 | 3 |
| ZBTB8OS | SREK1IP1 | 0.76683 | 3 | 0 | 3 |
| ZBTB8OS | COCH | 0.76039 | 3 | 0 | 3 |
| ZBTB8OS | RPL26L1 | 0.747021 | 4 | 0 | 4 |
| ZBTB8OS | LRP8 | 0.745887 | 3 | 0 | 3 |
| ZBTB8OS | VEZT | 0.740442 | 4 | 0 | 3 |
| ZBTB8OS | TRIP11 | 0.737528 | 3 | 0 | 3 |
| ZBTB8OS | SLC10A7 | 0.73657 | 3 | 0 | 3 |
| ZBTB8OS | C11orf80 | 0.734599 | 3 | 0 | 3 |
| ZBTB8OS | BAG5 | 0.725921 | 3 | 0 | 3 |
| ZBTB8OS | DNAJA2 | 0.723959 | 3 | 0 | 3 |
| ZBTB8OS | RACGAP1 | 0.721913 | 3 | 0 | 3 |
| ZBTB8OS | GFM2 | 0.711675 | 3 | 0 | 3 |
| ZBTB8OS | GPKOW | 0.711128 | 3 | 0 | 3 |
| ZBTB8OS | MTCH2 | 0.710844 | 3 | 0 | 3 |
| ZBTB8OS | DECR2 | 0.71053 | 3 | 0 | 3 |
| ZBTB8OS | RIOK2 | 0.70943 | 3 | 0 | 3 |
| ZBTB8OS | MYH3 | 0.709414 | 3 | 0 | 3 |
For details and further investigation, click here
