| Full name: glutaredoxin 2 | Alias Symbol: GRX2|bA101E13.1 | ||
| Type: protein-coding gene | Cytoband: 1q31.2 | ||
| Entrez ID: 51022 | HGNC ID: HGNC:16065 | Ensembl Gene: ENSG00000023572 | OMIM ID: 606820 |
| Drug and gene relationship at DGIdb | |||
Expression of GLRX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GLRX2 | 51022 | 219933_at | 0.4572 | 0.2917 | |
| GSE20347 | GLRX2 | 51022 | 219933_at | 0.1069 | 0.6312 | |
| GSE23400 | GLRX2 | 51022 | 219933_at | 0.1689 | 0.0121 | |
| GSE26886 | GLRX2 | 51022 | 219933_at | -0.0953 | 0.6114 | |
| GSE29001 | GLRX2 | 51022 | 219933_at | -0.0043 | 0.9878 | |
| GSE38129 | GLRX2 | 51022 | 219933_at | 0.1963 | 0.1731 | |
| GSE45670 | GLRX2 | 51022 | 219933_at | 0.2654 | 0.0372 | |
| GSE53622 | GLRX2 | 51022 | 65980 | -0.1774 | 0.0076 | |
| GSE53624 | GLRX2 | 51022 | 65980 | 0.0121 | 0.9060 | |
| GSE63941 | GLRX2 | 51022 | 219933_at | -0.5476 | 0.1948 | |
| GSE77861 | GLRX2 | 51022 | 219933_at | -0.2212 | 0.5793 | |
| GSE97050 | GLRX2 | 51022 | A_23_P160503 | 0.0324 | 0.9373 | |
| SRP007169 | GLRX2 | 51022 | RNAseq | -0.9372 | 0.0498 | |
| SRP008496 | GLRX2 | 51022 | RNAseq | -0.5946 | 0.1435 | |
| SRP064894 | GLRX2 | 51022 | RNAseq | 0.3854 | 0.0524 | |
| SRP133303 | GLRX2 | 51022 | RNAseq | 0.2243 | 0.2944 | |
| SRP159526 | GLRX2 | 51022 | RNAseq | -0.1488 | 0.6766 | |
| SRP193095 | GLRX2 | 51022 | RNAseq | -0.2461 | 0.1071 | |
| SRP219564 | GLRX2 | 51022 | RNAseq | 0.3866 | 0.4042 | |
| TCGA | GLRX2 | 51022 | RNAseq | 0.1034 | 0.1670 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GLRX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GLRX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GLRX2 | 51022 | 9 | 1 | 20 | |
| GSE20123 | GLRX2 | 51022 | 9 | 1 | 20 | |
| GSE43470 | GLRX2 | 51022 | 5 | 1 | 37 | |
| GSE46452 | GLRX2 | 51022 | 3 | 1 | 55 | |
| GSE47630 | GLRX2 | 51022 | 14 | 0 | 26 | |
| GSE54993 | GLRX2 | 51022 | 0 | 6 | 64 | |
| GSE54994 | GLRX2 | 51022 | 15 | 0 | 38 | |
| GSE60625 | GLRX2 | 51022 | 0 | 0 | 11 | |
| GSE74703 | GLRX2 | 51022 | 5 | 1 | 30 | |
| GSE74704 | GLRX2 | 51022 | 3 | 1 | 16 | |
| TCGA | GLRX2 | 51022 | 41 | 7 | 48 |
Total number of gains: 104; Total number of losses: 19; Total Number of normals: 365.
Somatic mutations of GLRX2:
Generating mutation plots.
Highly correlated genes for GLRX2:
Showing top 20/211 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GLRX2 | EWSR1 | 0.832386 | 3 | 0 | 3 |
| GLRX2 | ZNF146 | 0.812533 | 3 | 0 | 3 |
| GLRX2 | TOMM40L | 0.802595 | 3 | 0 | 3 |
| GLRX2 | POLR1B | 0.802124 | 3 | 0 | 3 |
| GLRX2 | TP53RK | 0.791944 | 3 | 0 | 3 |
| GLRX2 | CARS2 | 0.786517 | 3 | 0 | 3 |
| GLRX2 | TUBGCP3 | 0.778494 | 3 | 0 | 3 |
| GLRX2 | UBQLN4 | 0.776594 | 3 | 0 | 3 |
| GLRX2 | SS18L1 | 0.776384 | 3 | 0 | 3 |
| GLRX2 | THUMPD2 | 0.772772 | 3 | 0 | 3 |
| GLRX2 | MRFAP1 | 0.758964 | 3 | 0 | 3 |
| GLRX2 | TEX10 | 0.747161 | 3 | 0 | 3 |
| GLRX2 | RBM26 | 0.73416 | 4 | 0 | 3 |
| GLRX2 | CPNE8 | 0.72609 | 3 | 0 | 3 |
| GLRX2 | BAG5 | 0.723379 | 3 | 0 | 3 |
| GLRX2 | CTDSPL | 0.715319 | 3 | 0 | 3 |
| GLRX2 | SETD6 | 0.71337 | 4 | 0 | 3 |
| GLRX2 | PIGG | 0.712942 | 3 | 0 | 3 |
| GLRX2 | FBXW2 | 0.712819 | 3 | 0 | 3 |
| GLRX2 | DECR1 | 0.697077 | 3 | 0 | 3 |
For details and further investigation, click here
