| Full name: THUMP domain containing 3 | Alias Symbol: DKFZP434F091 | ||
| Type: protein-coding gene | Cytoband: 3p25.3 | ||
| Entrez ID: 25917 | HGNC ID: HGNC:24493 | Ensembl Gene: ENSG00000134077 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of THUMPD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | THUMPD3 | 25917 | 223804_s_at | -0.0871 | 0.8476 | |
| GSE26886 | THUMPD3 | 25917 | 223804_s_at | -0.3887 | 0.0742 | |
| GSE45670 | THUMPD3 | 25917 | 242377_x_at | 0.0165 | 0.8871 | |
| GSE53622 | THUMPD3 | 25917 | 26443 | -0.0350 | 0.5288 | |
| GSE53624 | THUMPD3 | 25917 | 26443 | 0.0126 | 0.8717 | |
| GSE63941 | THUMPD3 | 25917 | 223804_s_at | 0.2628 | 0.4672 | |
| GSE77861 | THUMPD3 | 25917 | 223804_s_at | -0.1322 | 0.2995 | |
| GSE97050 | THUMPD3 | 25917 | A_23_P212213 | -0.1025 | 0.6175 | |
| SRP007169 | THUMPD3 | 25917 | RNAseq | 0.4573 | 0.3329 | |
| SRP008496 | THUMPD3 | 25917 | RNAseq | 0.1972 | 0.5079 | |
| SRP064894 | THUMPD3 | 25917 | RNAseq | -0.3343 | 0.0147 | |
| SRP133303 | THUMPD3 | 25917 | RNAseq | -0.1235 | 0.4059 | |
| SRP159526 | THUMPD3 | 25917 | RNAseq | -0.1135 | 0.5937 | |
| SRP193095 | THUMPD3 | 25917 | RNAseq | -0.3027 | 0.0016 | |
| SRP219564 | THUMPD3 | 25917 | RNAseq | -0.5587 | 0.0523 | |
| TCGA | THUMPD3 | 25917 | RNAseq | -0.0354 | 0.5077 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by THUMPD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of THUMPD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | THUMPD3 | 25917 | 1 | 18 | 11 | |
| GSE20123 | THUMPD3 | 25917 | 1 | 18 | 11 | |
| GSE43470 | THUMPD3 | 25917 | 0 | 21 | 22 | |
| GSE46452 | THUMPD3 | 25917 | 2 | 17 | 40 | |
| GSE47630 | THUMPD3 | 25917 | 2 | 22 | 16 | |
| GSE54993 | THUMPD3 | 25917 | 6 | 1 | 63 | |
| GSE54994 | THUMPD3 | 25917 | 3 | 31 | 19 | |
| GSE60625 | THUMPD3 | 25917 | 5 | 0 | 6 | |
| GSE74703 | THUMPD3 | 25917 | 0 | 17 | 19 | |
| GSE74704 | THUMPD3 | 25917 | 1 | 11 | 8 | |
| TCGA | THUMPD3 | 25917 | 5 | 65 | 26 |
Total number of gains: 26; Total number of losses: 221; Total Number of normals: 241.
Somatic mutations of THUMPD3:
Generating mutation plots.
Highly correlated genes for THUMPD3:
Showing top 20/374 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| THUMPD3 | ZNF83 | 0.767948 | 3 | 0 | 3 |
| THUMPD3 | ANO10 | 0.766846 | 3 | 0 | 3 |
| THUMPD3 | RREB1 | 0.759855 | 4 | 0 | 4 |
| THUMPD3 | YME1L1 | 0.757747 | 3 | 0 | 3 |
| THUMPD3 | AMPD3 | 0.756411 | 3 | 0 | 3 |
| THUMPD3 | HDHD2 | 0.751466 | 3 | 0 | 3 |
| THUMPD3 | BBIP1 | 0.751427 | 3 | 0 | 3 |
| THUMPD3 | SREK1IP1 | 0.750345 | 3 | 0 | 3 |
| THUMPD3 | DAAM1 | 0.749514 | 4 | 0 | 4 |
| THUMPD3 | NUDT15 | 0.74947 | 3 | 0 | 3 |
| THUMPD3 | RANBP6 | 0.747876 | 3 | 0 | 3 |
| THUMPD3 | ZFP36L2 | 0.740859 | 3 | 0 | 3 |
| THUMPD3 | NDUFS1 | 0.740192 | 3 | 0 | 3 |
| THUMPD3 | SKAP2 | 0.728399 | 3 | 0 | 3 |
| THUMPD3 | IPMK | 0.727156 | 4 | 0 | 4 |
| THUMPD3 | ZCCHC10 | 0.725808 | 4 | 0 | 4 |
| THUMPD3 | AASDHPPT | 0.722552 | 3 | 0 | 3 |
| THUMPD3 | PPIP5K2 | 0.720926 | 3 | 0 | 3 |
| THUMPD3 | POLR2L | 0.719397 | 3 | 0 | 3 |
| THUMPD3 | ATG12 | 0.719192 | 3 | 0 | 3 |
For details and further investigation, click here
