BCL9L

 

Full name: BCL9 like Alias Symbol: DLNB11|B9L|Bcl9-2
Type: protein-coding gene Cytoband: 11q23.3
Entrez ID: 283149 HGNC ID: HGNC:23688 Ensembl Gene: ENSG00000186174 OMIM ID: 609004
Drug and gene relationship at DGIdb

 

Expression of BCL9L:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BCL9L 283149 227616_at 0.4376 0.4284
GSE26886 BCL9L 283149 227616_at 0.2379 0.2673
GSE45670 BCL9L 283149 228065_at -0.0846 0.5173
GSE53622 BCL9L 283149 62237 0.1872 0.0010
GSE53624 BCL9L 283149 62237 0.2182 0.0021
GSE63941 BCL9L 283149 227616_at 1.3016 0.0010
GSE77861 BCL9L 283149 227616_at 0.1651 0.2215
GSE97050 BCL9L 283149 A_24_P134816 -0.2435 0.2757
SRP007169 BCL9L 283149 RNAseq -0.5819 0.2151
SRP008496 BCL9L 283149 RNAseq -0.4274 0.1212
SRP064894 BCL9L 283149 RNAseq -0.7267 0.0185
SRP133303 BCL9L 283149 RNAseq -0.2414 0.1385
SRP159526 BCL9L 283149 RNAseq -0.0258 0.9275
SRP193095 BCL9L 283149 RNAseq -0.1189 0.5220
SRP219564 BCL9L 283149 RNAseq -0.4682 0.1490
TCGA BCL9L 283149 RNAseq 0.0619 0.1779

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by BCL9L expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of BCL9L:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 BCL9L 283149 2 11 17
GSE20123 BCL9L 283149 2 11 17
GSE43470 BCL9L 283149 2 8 33
GSE46452 BCL9L 283149 3 26 30
GSE47630 BCL9L 283149 2 19 19
GSE54993 BCL9L 283149 10 0 60
GSE54994 BCL9L 283149 5 19 29
GSE60625 BCL9L 283149 0 3 8
GSE74703 BCL9L 283149 1 5 30
GSE74704 BCL9L 283149 1 7 12
TCGA BCL9L 283149 4 51 41

Total number of gains: 32; Total number of losses: 160; Total Number of normals: 296.  


 

Somatic mutations of BCL9L:

 

Generating mutation plots.

 

Highly correlated genes for BCL9L:

 

Showing top 20/444 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BCL9LSREBF10.8526303
BCL9LRBM170.831367303
BCL9LZNF6910.812653303
BCL9LMED90.80639303
BCL9LLYAR0.778989303
BCL9LMRPL380.774192303
BCL9LREC80.772537303
BCL9LTMEM110.753968303
BCL9LPSMB70.747778303
BCL9LEEF1D0.746091303
BCL9LSRSF110.741805303
BCL9LPIAS40.741582303
BCL9LGRIN3B0.738137303
BCL9LCMTM40.733963303
BCL9LGPS20.732971303
BCL9LDCAKD0.732811303
BCL9LUBAC10.728071303
BCL9LDNAH140.725326303
BCL9LMIA30.72529303
BCL9LZGPAT0.724442403

For details and further investigation, click here