| Full name: UBA domain containing 1 | Alias Symbol: GBDR1|KPC2 | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 10422 | HGNC ID: HGNC:30221 | Ensembl Gene: ENSG00000130560 | OMIM ID: 608129 |
| Drug and gene relationship at DGIdb | |||
Expression of UBAC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBAC1 | 10422 | 202151_s_at | 0.0637 | 0.8777 | |
| GSE20347 | UBAC1 | 10422 | 202151_s_at | -0.0285 | 0.8514 | |
| GSE23400 | UBAC1 | 10422 | 202151_s_at | 0.1165 | 0.1510 | |
| GSE26886 | UBAC1 | 10422 | 202151_s_at | -0.0690 | 0.8068 | |
| GSE29001 | UBAC1 | 10422 | 202151_s_at | 0.0165 | 0.9731 | |
| GSE38129 | UBAC1 | 10422 | 202151_s_at | 0.0920 | 0.4508 | |
| GSE45670 | UBAC1 | 10422 | 202151_s_at | 0.2306 | 0.0683 | |
| GSE53622 | UBAC1 | 10422 | 12589 | -0.1517 | 0.0400 | |
| GSE53624 | UBAC1 | 10422 | 12589 | 0.2392 | 0.0002 | |
| GSE63941 | UBAC1 | 10422 | 202151_s_at | 1.0837 | 0.0432 | |
| GSE77861 | UBAC1 | 10422 | 202151_s_at | 0.4210 | 0.0729 | |
| GSE97050 | UBAC1 | 10422 | A_23_P60324 | -0.3813 | 0.1581 | |
| SRP007169 | UBAC1 | 10422 | RNAseq | 0.5497 | 0.2189 | |
| SRP008496 | UBAC1 | 10422 | RNAseq | 0.6547 | 0.0138 | |
| SRP064894 | UBAC1 | 10422 | RNAseq | 0.4364 | 0.0532 | |
| SRP133303 | UBAC1 | 10422 | RNAseq | 0.3116 | 0.1103 | |
| SRP159526 | UBAC1 | 10422 | RNAseq | 0.3296 | 0.2323 | |
| SRP193095 | UBAC1 | 10422 | RNAseq | 0.1160 | 0.3324 | |
| SRP219564 | UBAC1 | 10422 | RNAseq | 0.0739 | 0.8701 | |
| TCGA | UBAC1 | 10422 | RNAseq | 0.1492 | 0.0139 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by UBAC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBAC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBAC1 | 10422 | 4 | 7 | 19 | |
| GSE20123 | UBAC1 | 10422 | 4 | 7 | 19 | |
| GSE43470 | UBAC1 | 10422 | 3 | 7 | 33 | |
| GSE46452 | UBAC1 | 10422 | 6 | 13 | 40 | |
| GSE47630 | UBAC1 | 10422 | 6 | 15 | 19 | |
| GSE54993 | UBAC1 | 10422 | 3 | 3 | 64 | |
| GSE54994 | UBAC1 | 10422 | 12 | 8 | 33 | |
| GSE60625 | UBAC1 | 10422 | 0 | 0 | 11 | |
| GSE74703 | UBAC1 | 10422 | 3 | 5 | 28 | |
| GSE74704 | UBAC1 | 10422 | 2 | 5 | 13 | |
| TCGA | UBAC1 | 10422 | 28 | 25 | 43 |
Total number of gains: 71; Total number of losses: 95; Total Number of normals: 322.
Somatic mutations of UBAC1:
Generating mutation plots.
Highly correlated genes for UBAC1:
Showing top 20/353 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBAC1 | CD99L2 | 0.801645 | 3 | 0 | 3 |
| UBAC1 | MECP2 | 0.762443 | 3 | 0 | 3 |
| UBAC1 | LGALS8 | 0.745934 | 3 | 0 | 3 |
| UBAC1 | ZHX2 | 0.737323 | 3 | 0 | 3 |
| UBAC1 | BCL9L | 0.728071 | 3 | 0 | 3 |
| UBAC1 | CD151 | 0.718456 | 3 | 0 | 3 |
| UBAC1 | DFFA | 0.709888 | 3 | 0 | 3 |
| UBAC1 | FGF12 | 0.70632 | 3 | 0 | 3 |
| UBAC1 | ARHGEF16 | 0.705028 | 3 | 0 | 3 |
| UBAC1 | PCBP2 | 0.6939 | 3 | 0 | 3 |
| UBAC1 | DAG1 | 0.69091 | 4 | 0 | 3 |
| UBAC1 | HCFC1R1 | 0.689808 | 4 | 0 | 3 |
| UBAC1 | RASD2 | 0.678822 | 3 | 0 | 3 |
| UBAC1 | FEZ2 | 0.666301 | 3 | 0 | 3 |
| UBAC1 | ANAPC16 | 0.665209 | 4 | 0 | 4 |
| UBAC1 | SND1 | 0.664496 | 3 | 0 | 3 |
| UBAC1 | ZNF74 | 0.663041 | 3 | 0 | 3 |
| UBAC1 | NHLRC2 | 0.662482 | 3 | 0 | 3 |
| UBAC1 | TMEM205 | 0.661473 | 4 | 0 | 3 |
| UBAC1 | VPS39 | 0.659476 | 4 | 0 | 3 |
For details and further investigation, click here
