| Full name: transmembrane protein 11 | Alias Symbol: PMI|PM1 | ||
| Type: protein-coding gene | Cytoband: 17p11.1 | ||
| Entrez ID: 8834 | HGNC ID: HGNC:16823 | Ensembl Gene: ENSG00000178307 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM11 | 8834 | 203437_at | 0.1806 | 0.4284 | |
| GSE20347 | TMEM11 | 8834 | 203437_at | 0.0160 | 0.9045 | |
| GSE23400 | TMEM11 | 8834 | 203437_at | 0.0970 | 0.1092 | |
| GSE26886 | TMEM11 | 8834 | 203437_at | 0.2560 | 0.1989 | |
| GSE29001 | TMEM11 | 8834 | 203437_at | 0.1494 | 0.3091 | |
| GSE38129 | TMEM11 | 8834 | 203437_at | 0.2239 | 0.0881 | |
| GSE45670 | TMEM11 | 8834 | 203437_at | 0.0519 | 0.6482 | |
| GSE53622 | TMEM11 | 8834 | 43325 | 0.0528 | 0.5022 | |
| GSE53624 | TMEM11 | 8834 | 43325 | 0.1466 | 0.0024 | |
| GSE63941 | TMEM11 | 8834 | 203437_at | 0.0723 | 0.8924 | |
| GSE77861 | TMEM11 | 8834 | 203437_at | 0.1830 | 0.3331 | |
| GSE97050 | TMEM11 | 8834 | A_23_P107036 | 0.0758 | 0.8282 | |
| SRP007169 | TMEM11 | 8834 | RNAseq | 0.0162 | 0.9685 | |
| SRP008496 | TMEM11 | 8834 | RNAseq | -0.3035 | 0.3339 | |
| SRP064894 | TMEM11 | 8834 | RNAseq | 0.4942 | 0.0816 | |
| SRP133303 | TMEM11 | 8834 | RNAseq | 0.1302 | 0.3665 | |
| SRP159526 | TMEM11 | 8834 | RNAseq | 0.0234 | 0.8795 | |
| SRP193095 | TMEM11 | 8834 | RNAseq | -0.3360 | 0.0122 | |
| SRP219564 | TMEM11 | 8834 | RNAseq | 0.2187 | 0.5344 | |
| TCGA | TMEM11 | 8834 | RNAseq | 0.1246 | 0.0286 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM11 | 8834 | 4 | 5 | 21 | |
| GSE20123 | TMEM11 | 8834 | 4 | 6 | 20 | |
| GSE43470 | TMEM11 | 8834 | 1 | 5 | 37 | |
| GSE46452 | TMEM11 | 8834 | 34 | 1 | 24 | |
| GSE47630 | TMEM11 | 8834 | 7 | 1 | 32 | |
| GSE54993 | TMEM11 | 8834 | 2 | 4 | 64 | |
| GSE54994 | TMEM11 | 8834 | 6 | 6 | 41 | |
| GSE60625 | TMEM11 | 8834 | 4 | 0 | 7 | |
| GSE74703 | TMEM11 | 8834 | 1 | 2 | 33 | |
| GSE74704 | TMEM11 | 8834 | 2 | 2 | 16 | |
| TCGA | TMEM11 | 8834 | 19 | 24 | 53 |
Total number of gains: 84; Total number of losses: 56; Total Number of normals: 348.
Somatic mutations of TMEM11:
Generating mutation plots.
Highly correlated genes for TMEM11:
Showing top 20/443 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM11 | ARHGEF19 | 0.792197 | 3 | 0 | 3 |
| TMEM11 | DNAJC11 | 0.760752 | 3 | 0 | 3 |
| TMEM11 | GRWD1 | 0.754646 | 4 | 0 | 4 |
| TMEM11 | BCL9L | 0.753968 | 3 | 0 | 3 |
| TMEM11 | SRRT | 0.750305 | 3 | 0 | 3 |
| TMEM11 | ZFYVE27 | 0.736504 | 3 | 0 | 3 |
| TMEM11 | PA2G4 | 0.733455 | 4 | 0 | 3 |
| TMEM11 | WDR5 | 0.724471 | 3 | 0 | 3 |
| TMEM11 | CDCA4 | 0.721302 | 3 | 0 | 3 |
| TMEM11 | PPP1R16A | 0.718997 | 3 | 0 | 3 |
| TMEM11 | ATXN7L3 | 0.718711 | 3 | 0 | 3 |
| TMEM11 | LIMK1 | 0.718537 | 3 | 0 | 3 |
| TMEM11 | PTPN9 | 0.718434 | 3 | 0 | 3 |
| TMEM11 | GORAB | 0.713891 | 3 | 0 | 3 |
| TMEM11 | ZNF628 | 0.713595 | 3 | 0 | 3 |
| TMEM11 | SAMD1 | 0.711993 | 4 | 0 | 3 |
| TMEM11 | DNMT1 | 0.71132 | 3 | 0 | 3 |
| TMEM11 | AGRN | 0.709424 | 3 | 0 | 3 |
| TMEM11 | STMN1 | 0.70932 | 3 | 0 | 3 |
| TMEM11 | WDR4 | 0.709218 | 4 | 0 | 4 |
For details and further investigation, click here
