| Full name: bone morphogenetic protein 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q21.21 | ||
| Entrez ID: 651 | HGNC ID: HGNC:1070 | Ensembl Gene: ENSG00000152785 | OMIM ID: 112263 |
| Drug and gene relationship at DGIdb | |||
Expression of BMP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BMP3 | 651 | 208244_at | -0.0532 | 0.8749 | |
| GSE20347 | BMP3 | 651 | 208244_at | -0.0268 | 0.6873 | |
| GSE23400 | BMP3 | 651 | 208244_at | -0.1323 | 0.0002 | |
| GSE26886 | BMP3 | 651 | 208244_at | 0.2943 | 0.0036 | |
| GSE29001 | BMP3 | 651 | 208244_at | -0.0274 | 0.8390 | |
| GSE38129 | BMP3 | 651 | 208244_at | -0.0827 | 0.2457 | |
| GSE45670 | BMP3 | 651 | 208244_at | -0.0433 | 0.6273 | |
| GSE53622 | BMP3 | 651 | 26399 | -0.6655 | 0.1534 | |
| GSE53624 | BMP3 | 651 | 26399 | -0.5393 | 0.0588 | |
| GSE63941 | BMP3 | 651 | 208244_at | 0.1954 | 0.2279 | |
| GSE77861 | BMP3 | 651 | 208244_at | -0.0209 | 0.8684 | |
| GSE97050 | BMP3 | 651 | A_23_P81058 | -1.1552 | 0.2433 | |
| SRP133303 | BMP3 | 651 | RNAseq | 0.2201 | 0.6926 | |
| TCGA | BMP3 | 651 | RNAseq | -1.0157 | 0.0686 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by BMP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BMP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BMP3 | 651 | 1 | 10 | 19 | |
| GSE20123 | BMP3 | 651 | 1 | 10 | 19 | |
| GSE43470 | BMP3 | 651 | 0 | 13 | 30 | |
| GSE46452 | BMP3 | 651 | 1 | 36 | 22 | |
| GSE47630 | BMP3 | 651 | 1 | 19 | 20 | |
| GSE54993 | BMP3 | 651 | 8 | 0 | 62 | |
| GSE54994 | BMP3 | 651 | 0 | 9 | 44 | |
| GSE60625 | BMP3 | 651 | 0 | 0 | 11 | |
| GSE74703 | BMP3 | 651 | 0 | 11 | 25 | |
| GSE74704 | BMP3 | 651 | 1 | 5 | 14 | |
| TCGA | BMP3 | 651 | 11 | 35 | 50 |
Total number of gains: 24; Total number of losses: 148; Total Number of normals: 316.
Somatic mutations of BMP3:
Generating mutation plots.
Highly correlated genes for BMP3:
Showing top 20/508 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BMP3 | IPO11 | 0.736388 | 3 | 0 | 3 |
| BMP3 | CACNB4 | 0.692982 | 4 | 0 | 4 |
| BMP3 | IQUB | 0.692517 | 3 | 0 | 3 |
| BMP3 | CSF3R | 0.684713 | 3 | 0 | 3 |
| BMP3 | MED14OS | 0.683561 | 3 | 0 | 3 |
| BMP3 | ITIH2 | 0.679214 | 4 | 0 | 4 |
| BMP3 | RIMKLA | 0.670652 | 4 | 0 | 3 |
| BMP3 | PLEKHA5 | 0.669256 | 3 | 0 | 3 |
| BMP3 | NUDT7 | 0.65785 | 4 | 0 | 3 |
| BMP3 | RILPL1 | 0.651508 | 3 | 0 | 3 |
| BMP3 | SOX3 | 0.650205 | 5 | 0 | 4 |
| BMP3 | MAPK12 | 0.649418 | 3 | 0 | 3 |
| BMP3 | KAT5 | 0.645352 | 3 | 0 | 3 |
| BMP3 | DOCK5 | 0.644419 | 3 | 0 | 3 |
| BMP3 | HTR2B | 0.644139 | 4 | 0 | 3 |
| BMP3 | MYADM | 0.642551 | 3 | 0 | 3 |
| BMP3 | CDKL2 | 0.642482 | 4 | 0 | 4 |
| BMP3 | KHDRBS2 | 0.641991 | 4 | 0 | 4 |
| BMP3 | EIF2D | 0.641934 | 4 | 0 | 4 |
| BMP3 | GSX1 | 0.640777 | 4 | 0 | 3 |
For details and further investigation, click here
