| Full name: IQ motif and ubiquitin domain containing | Alias Symbol: FLJ35834 | ||
| Type: protein-coding gene | Cytoband: 7q31.32 | ||
| Entrez ID: 154865 | HGNC ID: HGNC:21995 | Ensembl Gene: ENSG00000164675 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of IQUB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IQUB | 154865 | 1568924_a_at | -0.2298 | 0.5595 | |
| GSE26886 | IQUB | 154865 | 1568924_a_at | -0.0596 | 0.5219 | |
| GSE45670 | IQUB | 154865 | 1568924_a_at | 0.1080 | 0.2331 | |
| GSE53622 | IQUB | 154865 | 92754 | -0.3403 | 0.2551 | |
| GSE53624 | IQUB | 154865 | 92754 | 0.4482 | 0.0029 | |
| GSE63941 | IQUB | 154865 | 1568924_a_at | -0.2018 | 0.2648 | |
| GSE77861 | IQUB | 154865 | 1568924_a_at | -0.0035 | 0.9763 | |
| GSE97050 | IQUB | 154865 | A_24_P203298 | -0.9760 | 0.1372 | |
| SRP133303 | IQUB | 154865 | RNAseq | 1.7676 | 0.0040 | |
| TCGA | IQUB | 154865 | RNAseq | -0.5265 | 0.1939 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by IQUB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IQUB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IQUB | 154865 | 6 | 2 | 22 | |
| GSE20123 | IQUB | 154865 | 7 | 2 | 21 | |
| GSE43470 | IQUB | 154865 | 2 | 4 | 37 | |
| GSE46452 | IQUB | 154865 | 8 | 1 | 50 | |
| GSE47630 | IQUB | 154865 | 7 | 4 | 29 | |
| GSE54993 | IQUB | 154865 | 3 | 5 | 62 | |
| GSE54994 | IQUB | 154865 | 9 | 7 | 37 | |
| GSE60625 | IQUB | 154865 | 0 | 0 | 11 | |
| GSE74703 | IQUB | 154865 | 2 | 4 | 30 | |
| GSE74704 | IQUB | 154865 | 5 | 2 | 13 | |
| TCGA | IQUB | 154865 | 27 | 21 | 48 |
Total number of gains: 76; Total number of losses: 52; Total Number of normals: 360.
Somatic mutations of IQUB:
Generating mutation plots.
Highly correlated genes for IQUB:
Showing top 20/246 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IQUB | CTNNA3 | 0.842839 | 3 | 0 | 3 |
| IQUB | PGR | 0.826404 | 3 | 0 | 3 |
| IQUB | NCAM1 | 0.820108 | 3 | 0 | 3 |
| IQUB | PRKG2 | 0.810149 | 3 | 0 | 3 |
| IQUB | MYOT | 0.800345 | 3 | 0 | 3 |
| IQUB | SGCA | 0.799702 | 3 | 0 | 3 |
| IQUB | GYG1 | 0.793728 | 3 | 0 | 3 |
| IQUB | PLEKHB1 | 0.785279 | 3 | 0 | 3 |
| IQUB | TRAK2 | 0.782395 | 3 | 0 | 3 |
| IQUB | MOAP1 | 0.782288 | 3 | 0 | 3 |
| IQUB | CACNA2D2 | 0.781271 | 3 | 0 | 3 |
| IQUB | ARHGEF25 | 0.780339 | 3 | 0 | 3 |
| IQUB | RBM24 | 0.777624 | 3 | 0 | 3 |
| IQUB | ALPK3 | 0.776486 | 3 | 0 | 3 |
| IQUB | ITPKB | 0.775073 | 3 | 0 | 3 |
| IQUB | ASB5 | 0.772416 | 3 | 0 | 3 |
| IQUB | OCRL | 0.769951 | 3 | 0 | 3 |
| IQUB | CACNB2 | 0.768247 | 3 | 0 | 3 |
| IQUB | CASQ1 | 0.767366 | 3 | 0 | 3 |
| IQUB | PIP5K1C | 0.765473 | 3 | 0 | 3 |
For details and further investigation, click here
