| Full name: inter-alpha-trypsin inhibitor heavy chain 2 | Alias Symbol: H2P | ||
| Type: protein-coding gene | Cytoband: 10p14 | ||
| Entrez ID: 3698 | HGNC ID: HGNC:6167 | Ensembl Gene: ENSG00000151655 | OMIM ID: 146640 |
| Drug and gene relationship at DGIdb | |||
Expression of ITIH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ITIH2 | 3698 | 204987_at | -0.1914 | 0.5647 | |
| GSE20347 | ITIH2 | 3698 | 204987_at | -0.0411 | 0.6850 | |
| GSE23400 | ITIH2 | 3698 | 204987_at | -0.0237 | 0.6339 | |
| GSE26886 | ITIH2 | 3698 | 204987_at | 0.0667 | 0.6524 | |
| GSE29001 | ITIH2 | 3698 | 204987_at | -0.2423 | 0.3365 | |
| GSE38129 | ITIH2 | 3698 | 204987_at | -0.0376 | 0.7298 | |
| GSE45670 | ITIH2 | 3698 | 204987_at | 0.0705 | 0.4032 | |
| GSE53622 | ITIH2 | 3698 | 17379 | 0.2546 | 0.0003 | |
| GSE53624 | ITIH2 | 3698 | 17379 | 0.3223 | 0.0002 | |
| GSE63941 | ITIH2 | 3698 | 204987_at | 0.2516 | 0.1026 | |
| GSE77861 | ITIH2 | 3698 | 204987_at | 0.0518 | 0.6949 | |
| SRP133303 | ITIH2 | 3698 | RNAseq | -0.9872 | 0.0017 | |
| TCGA | ITIH2 | 3698 | RNAseq | -1.9596 | 0.0009 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ITIH2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ITIH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ITIH2 | 3698 | 4 | 8 | 18 | |
| GSE20123 | ITIH2 | 3698 | 4 | 7 | 19 | |
| GSE43470 | ITIH2 | 3698 | 3 | 6 | 34 | |
| GSE46452 | ITIH2 | 3698 | 2 | 14 | 43 | |
| GSE47630 | ITIH2 | 3698 | 5 | 15 | 20 | |
| GSE54993 | ITIH2 | 3698 | 11 | 0 | 59 | |
| GSE54994 | ITIH2 | 3698 | 4 | 10 | 39 | |
| GSE60625 | ITIH2 | 3698 | 0 | 0 | 11 | |
| GSE74703 | ITIH2 | 3698 | 2 | 4 | 30 | |
| GSE74704 | ITIH2 | 3698 | 1 | 6 | 13 | |
| TCGA | ITIH2 | 3698 | 19 | 26 | 51 |
Total number of gains: 55; Total number of losses: 96; Total Number of normals: 337.
Somatic mutations of ITIH2:
Generating mutation plots.
Highly correlated genes for ITIH2:
Showing top 20/601 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ITIH2 | PSG9 | 0.724432 | 3 | 0 | 3 |
| ITIH2 | ODF1 | 0.696122 | 5 | 0 | 5 |
| ITIH2 | CIITA | 0.690302 | 5 | 0 | 4 |
| ITIH2 | BMP3 | 0.679214 | 4 | 0 | 4 |
| ITIH2 | DRD5 | 0.677014 | 4 | 0 | 4 |
| ITIH2 | SLC12A5 | 0.669978 | 6 | 0 | 5 |
| ITIH2 | RPS6KA6 | 0.669943 | 5 | 0 | 4 |
| ITIH2 | PSG2 | 0.669145 | 4 | 0 | 4 |
| ITIH2 | CLCA1 | 0.66819 | 5 | 0 | 5 |
| ITIH2 | KCNC1 | 0.666558 | 7 | 0 | 5 |
| ITIH2 | OR2H2 | 0.664297 | 6 | 0 | 5 |
| ITIH2 | ULK4 | 0.651285 | 4 | 0 | 3 |
| ITIH2 | PIGQ | 0.649608 | 3 | 0 | 3 |
| ITIH2 | TUBA8 | 0.647984 | 4 | 0 | 3 |
| ITIH2 | NPY2R | 0.647863 | 3 | 0 | 3 |
| ITIH2 | CLDN18 | 0.647689 | 3 | 0 | 3 |
| ITIH2 | CCDC87 | 0.646602 | 4 | 0 | 3 |
| ITIH2 | ACSBG2 | 0.645878 | 6 | 0 | 5 |
| ITIH2 | ENAM | 0.640717 | 3 | 0 | 3 |
| ITIH2 | TFAP4 | 0.637985 | 5 | 0 | 4 |
For details and further investigation, click here
