| Full name: pleckstrin homology domain containing A5 | Alias Symbol: PEPP2|KIAA1686|FLJ10667 | ||
| Type: protein-coding gene | Cytoband: 12p12.3 | ||
| Entrez ID: 54477 | HGNC ID: HGNC:30036 | Ensembl Gene: ENSG00000052126 | OMIM ID: 607770 |
| Drug and gene relationship at DGIdb | |||
Expression of PLEKHA5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLEKHA5 | 54477 | 220952_s_at | -0.9731 | 0.0929 | |
| GSE20347 | PLEKHA5 | 54477 | 220952_s_at | -0.3982 | 0.0040 | |
| GSE23400 | PLEKHA5 | 54477 | 220952_s_at | -0.6132 | 0.0000 | |
| GSE26886 | PLEKHA5 | 54477 | 220952_s_at | -0.2256 | 0.6002 | |
| GSE29001 | PLEKHA5 | 54477 | 220952_s_at | -0.5784 | 0.0993 | |
| GSE38129 | PLEKHA5 | 54477 | 220952_s_at | -0.5830 | 0.0146 | |
| GSE45670 | PLEKHA5 | 54477 | 220952_s_at | -0.6324 | 0.0001 | |
| GSE53622 | PLEKHA5 | 54477 | 95186 | -0.4211 | 0.0000 | |
| GSE53624 | PLEKHA5 | 54477 | 95186 | -0.4318 | 0.0000 | |
| GSE63941 | PLEKHA5 | 54477 | 220952_s_at | -0.9360 | 0.1541 | |
| GSE77861 | PLEKHA5 | 54477 | 220952_s_at | 0.0993 | 0.8249 | |
| GSE97050 | PLEKHA5 | 54477 | A_33_P3393650 | -1.0948 | 0.0887 | |
| SRP007169 | PLEKHA5 | 54477 | RNAseq | -0.3946 | 0.2486 | |
| SRP008496 | PLEKHA5 | 54477 | RNAseq | 0.0549 | 0.8573 | |
| SRP064894 | PLEKHA5 | 54477 | RNAseq | -1.0728 | 0.0001 | |
| SRP133303 | PLEKHA5 | 54477 | RNAseq | -0.1045 | 0.4730 | |
| SRP159526 | PLEKHA5 | 54477 | RNAseq | -0.3992 | 0.0451 | |
| SRP193095 | PLEKHA5 | 54477 | RNAseq | -0.3820 | 0.0004 | |
| SRP219564 | PLEKHA5 | 54477 | RNAseq | -0.4571 | 0.4099 | |
| TCGA | PLEKHA5 | 54477 | RNAseq | -0.0434 | 0.5029 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PLEKHA5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLEKHA5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLEKHA5 | 54477 | 9 | 2 | 19 | |
| GSE20123 | PLEKHA5 | 54477 | 9 | 2 | 19 | |
| GSE43470 | PLEKHA5 | 54477 | 9 | 4 | 30 | |
| GSE46452 | PLEKHA5 | 54477 | 10 | 1 | 48 | |
| GSE47630 | PLEKHA5 | 54477 | 14 | 1 | 25 | |
| GSE54993 | PLEKHA5 | 54477 | 1 | 9 | 60 | |
| GSE54994 | PLEKHA5 | 54477 | 11 | 3 | 39 | |
| GSE60625 | PLEKHA5 | 54477 | 0 | 1 | 10 | |
| GSE74703 | PLEKHA5 | 54477 | 9 | 3 | 24 | |
| GSE74704 | PLEKHA5 | 54477 | 6 | 1 | 13 | |
| TCGA | PLEKHA5 | 54477 | 43 | 6 | 47 |
Total number of gains: 121; Total number of losses: 33; Total Number of normals: 334.
Somatic mutations of PLEKHA5:
Generating mutation plots.
Highly correlated genes for PLEKHA5:
Showing top 20/506 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLEKHA5 | SRP14 | 0.789675 | 3 | 0 | 3 |
| PLEKHA5 | GH2 | 0.778077 | 3 | 0 | 3 |
| PLEKHA5 | PRADC1 | 0.74518 | 3 | 0 | 3 |
| PLEKHA5 | BECN1 | 0.732867 | 3 | 0 | 3 |
| PLEKHA5 | APBA1 | 0.723724 | 3 | 0 | 3 |
| PLEKHA5 | GPHN | 0.722604 | 3 | 0 | 3 |
| PLEKHA5 | TRA2A | 0.718201 | 3 | 0 | 3 |
| PLEKHA5 | ST6GAL2 | 0.714793 | 3 | 0 | 3 |
| PLEKHA5 | BCAP29 | 0.705566 | 4 | 0 | 4 |
| PLEKHA5 | CFL2 | 0.693953 | 4 | 0 | 4 |
| PLEKHA5 | RFX2 | 0.691823 | 4 | 0 | 3 |
| PLEKHA5 | CNST | 0.689779 | 5 | 0 | 5 |
| PLEKHA5 | RYR3 | 0.689231 | 4 | 0 | 4 |
| PLEKHA5 | CRADD | 0.688159 | 3 | 0 | 3 |
| PLEKHA5 | COX7A1 | 0.687791 | 5 | 0 | 5 |
| PLEKHA5 | CPXM2 | 0.683964 | 3 | 0 | 3 |
| PLEKHA5 | OGN | 0.682786 | 4 | 0 | 3 |
| PLEKHA5 | RASSF3 | 0.68146 | 4 | 0 | 3 |
| PLEKHA5 | ESYT2 | 0.67926 | 4 | 0 | 3 |
| PLEKHA5 | BRWD1 | 0.675067 | 3 | 0 | 3 |
For details and further investigation, click here
