| Full name: C-C motif chemokine ligand 1 | Alias Symbol: I-309|TCA3|P500|SISe | ||
| Type: protein-coding gene | Cytoband: 17q12 | ||
| Entrez ID: 6346 | HGNC ID: HGNC:10609 | Ensembl Gene: ENSG00000108702 | OMIM ID: 182281 |
| Drug and gene relationship at DGIdb | |||
CCL1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04062 | Chemokine signaling pathway |
Expression of CCL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCL1 | 6346 | 207533_at | -0.0652 | 0.7576 | |
| GSE20347 | CCL1 | 6346 | 207533_at | -0.0298 | 0.7136 | |
| GSE23400 | CCL1 | 6346 | 207533_at | -0.1177 | 0.0109 | |
| GSE26886 | CCL1 | 6346 | 207533_at | 0.0388 | 0.7346 | |
| GSE29001 | CCL1 | 6346 | 207533_at | -0.0877 | 0.5589 | |
| GSE38129 | CCL1 | 6346 | 207533_at | -0.0646 | 0.3862 | |
| GSE45670 | CCL1 | 6346 | 207533_at | 0.0876 | 0.2756 | |
| GSE53622 | CCL1 | 6346 | 2846 | 0.0590 | 0.4323 | |
| GSE53624 | CCL1 | 6346 | 2846 | 0.2321 | 0.0003 | |
| GSE63941 | CCL1 | 6346 | 207533_at | 0.1579 | 0.3184 | |
| GSE77861 | CCL1 | 6346 | 207533_at | -0.1009 | 0.3474 | |
| TCGA | CCL1 | 6346 | RNAseq | 1.3075 | 0.3165 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCL1 | 6346 | 5 | 1 | 24 | |
| GSE20123 | CCL1 | 6346 | 5 | 1 | 24 | |
| GSE43470 | CCL1 | 6346 | 1 | 2 | 40 | |
| GSE46452 | CCL1 | 6346 | 34 | 0 | 25 | |
| GSE47630 | CCL1 | 6346 | 7 | 1 | 32 | |
| GSE54993 | CCL1 | 6346 | 3 | 3 | 64 | |
| GSE54994 | CCL1 | 6346 | 7 | 6 | 40 | |
| GSE60625 | CCL1 | 6346 | 4 | 0 | 7 | |
| GSE74703 | CCL1 | 6346 | 1 | 1 | 34 | |
| GSE74704 | CCL1 | 6346 | 3 | 1 | 16 | |
| TCGA | CCL1 | 6346 | 20 | 9 | 67 |
Total number of gains: 90; Total number of losses: 25; Total Number of normals: 373.
Somatic mutations of CCL1:
Generating mutation plots.
Highly correlated genes for CCL1:
Showing top 20/854 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCL1 | NUDT7 | 0.712472 | 4 | 0 | 4 |
| CCL1 | CGA | 0.706877 | 4 | 0 | 4 |
| CCL1 | CITED1 | 0.699881 | 3 | 0 | 3 |
| CCL1 | GP2 | 0.699455 | 4 | 0 | 4 |
| CCL1 | NOS1 | 0.699435 | 5 | 0 | 4 |
| CCL1 | ZP2 | 0.692059 | 3 | 0 | 3 |
| CCL1 | LINC00474 | 0.690758 | 4 | 0 | 4 |
| CCL1 | CLDN6 | 0.681102 | 3 | 0 | 3 |
| CCL1 | FGF5 | 0.678196 | 3 | 0 | 3 |
| CCL1 | HDAC11 | 0.676985 | 4 | 0 | 4 |
| CCL1 | BPIFA1 | 0.675919 | 5 | 0 | 5 |
| CCL1 | GPR12 | 0.675312 | 4 | 0 | 4 |
| CCL1 | RGSL1 | 0.674412 | 5 | 0 | 4 |
| CCL1 | GABRA1 | 0.67416 | 5 | 0 | 5 |
| CCL1 | KIR2DS2 | 0.673926 | 4 | 0 | 4 |
| CCL1 | OR10C1 | 0.672057 | 3 | 0 | 3 |
| CCL1 | UBE2D4 | 0.670705 | 3 | 0 | 3 |
| CCL1 | PHF7 | 0.667073 | 5 | 0 | 5 |
| CCL1 | NPPA | 0.665329 | 4 | 0 | 4 |
| CCL1 | SLC17A3 | 0.66423 | 4 | 0 | 3 |
For details and further investigation, click here
