TMEM200A

 

Full name: transmembrane protein 200A Alias Symbol: TTMC
Type: protein-coding gene Cytoband: 6q23.1
Entrez ID: 114801 HGNC ID: HGNC:21075 Ensembl Gene: ENSG00000164484 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TMEM200A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMEM200A 114801 234994_at 1.3281 0.3139
GSE26886 TMEM200A 114801 234994_at 0.3552 0.5766
GSE45670 TMEM200A 114801 234994_at -0.2420 0.5415
GSE53622 TMEM200A 114801 32728 1.6296 0.0000
GSE53624 TMEM200A 114801 32728 1.5245 0.0000
GSE63941 TMEM200A 114801 234994_at -6.4473 0.0004
GSE77861 TMEM200A 114801 234994_at 0.0363 0.7760
GSE97050 TMEM200A 114801 A_32_P40288 0.4388 0.1602
SRP007169 TMEM200A 114801 RNAseq 1.9359 0.0090
SRP064894 TMEM200A 114801 RNAseq 1.7995 0.0000
SRP133303 TMEM200A 114801 RNAseq 1.5568 0.0000
SRP159526 TMEM200A 114801 RNAseq 1.7612 0.0044
SRP193095 TMEM200A 114801 RNAseq 0.2261 0.5573
SRP219564 TMEM200A 114801 RNAseq 1.4390 0.0063
TCGA TMEM200A 114801 RNAseq -0.4568 0.0297

Upregulated datasets: 7; Downregulated datasets: 1.  


 

Survival by TMEM200A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TMEM200A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMEM200A 114801 1 4 25
GSE20123 TMEM200A 114801 1 3 26
GSE43470 TMEM200A 114801 5 0 38
GSE46452 TMEM200A 114801 2 11 46
GSE47630 TMEM200A 114801 9 4 27
GSE54993 TMEM200A 114801 3 3 64
GSE54994 TMEM200A 114801 9 7 37
GSE60625 TMEM200A 114801 0 1 10
GSE74703 TMEM200A 114801 4 0 32
GSE74704 TMEM200A 114801 0 1 19
TCGA TMEM200A 114801 11 18 67

Total number of gains: 45; Total number of losses: 52; Total Number of normals: 391.  


 

Somatic mutations of TMEM200A:

 

Generating mutation plots.

 

Highly correlated genes for TMEM200A:

 

Showing top 20/899 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMEM200AZNF5950.815084303
TMEM200AFCGR3A0.788171303
TMEM200AOLR10.76206404
TMEM200ASIDT20.759605303
TMEM200AANKRD440.745572303
TMEM200APLXNC10.743565606
TMEM200ASH2B30.742842707
TMEM200AACAP10.738351303
TMEM200ARAB420.735853303
TMEM200ASPON20.733704303
TMEM200APRRX10.733692808
TMEM200ADPY19L10.733373404
TMEM200ATRPV20.731079707
TMEM200ASNX120.730018303
TMEM200AWDR540.729046303
TMEM200ATIGIT0.724352303
TMEM200ARWDD2A0.723417303
TMEM200AB3GALT20.721163303
TMEM200ABTN2A10.719834404
TMEM200ACYBA0.715035303

For details and further investigation, click here