| Full name: chromosome 8 open reading frame 76 | Alias Symbol: FLJ14825 | ||
| Type: protein-coding gene | Cytoband: 8q24.13 | ||
| Entrez ID: 84933 | HGNC ID: HGNC:25924 | Ensembl Gene: ENSG00000189376 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C8orf76:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C8orf76 | 84933 | 225702_at | 0.8219 | 0.1805 | |
| GSE26886 | C8orf76 | 84933 | 225702_at | 0.4541 | 0.0316 | |
| GSE45670 | C8orf76 | 84933 | 225702_at | 0.5764 | 0.0005 | |
| GSE53622 | C8orf76 | 84933 | 60385 | 0.5142 | 0.0000 | |
| GSE53624 | C8orf76 | 84933 | 60385 | 0.3079 | 0.0001 | |
| GSE63941 | C8orf76 | 84933 | 225702_at | 0.3196 | 0.5875 | |
| GSE77861 | C8orf76 | 84933 | 225702_at | 0.1961 | 0.3604 | |
| GSE97050 | C8orf76 | 84933 | A_23_P31747 | 0.2986 | 0.4040 | |
| SRP007169 | C8orf76 | 84933 | RNAseq | -0.8178 | 0.0619 | |
| SRP008496 | C8orf76 | 84933 | RNAseq | -0.5326 | 0.0435 | |
| SRP064894 | C8orf76 | 84933 | RNAseq | 0.1895 | 0.4152 | |
| SRP133303 | C8orf76 | 84933 | RNAseq | 0.4577 | 0.0000 | |
| SRP159526 | C8orf76 | 84933 | RNAseq | 0.0605 | 0.7831 | |
| SRP193095 | C8orf76 | 84933 | RNAseq | 0.0811 | 0.5936 | |
| SRP219564 | C8orf76 | 84933 | RNAseq | 0.3692 | 0.5147 | |
| TCGA | C8orf76 | 84933 | RNAseq | 0.3275 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C8orf76 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C8orf76:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C8orf76 | 84933 | 19 | 1 | 10 | |
| GSE20123 | C8orf76 | 84933 | 20 | 1 | 9 | |
| GSE43470 | C8orf76 | 84933 | 22 | 0 | 21 | |
| GSE46452 | C8orf76 | 84933 | 27 | 0 | 32 | |
| GSE47630 | C8orf76 | 84933 | 24 | 0 | 16 | |
| GSE54993 | C8orf76 | 84933 | 0 | 21 | 49 | |
| GSE54994 | C8orf76 | 84933 | 37 | 1 | 15 | |
| GSE60625 | C8orf76 | 84933 | 0 | 4 | 7 | |
| GSE74703 | C8orf76 | 84933 | 19 | 0 | 17 | |
| GSE74704 | C8orf76 | 84933 | 13 | 1 | 6 | |
| TCGA | C8orf76 | 84933 | 67 | 1 | 28 |
Total number of gains: 248; Total number of losses: 30; Total Number of normals: 210.
Somatic mutations of C8orf76:
Generating mutation plots.
Highly correlated genes for C8orf76:
Showing top 20/1185 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C8orf76 | POLR2B | 0.856552 | 3 | 0 | 3 |
| C8orf76 | COX16 | 0.825144 | 3 | 0 | 3 |
| C8orf76 | ZC3H3 | 0.810471 | 4 | 0 | 4 |
| C8orf76 | RHBDF2 | 0.7911 | 3 | 0 | 3 |
| C8orf76 | SLC52A2 | 0.790778 | 3 | 0 | 3 |
| C8orf76 | MRPL9 | 0.7774 | 3 | 0 | 3 |
| C8orf76 | CBFA2T2 | 0.774255 | 3 | 0 | 3 |
| C8orf76 | GABPB1 | 0.772244 | 3 | 0 | 3 |
| C8orf76 | SEC61A1 | 0.771479 | 4 | 0 | 4 |
| C8orf76 | ADRM1 | 0.767929 | 4 | 0 | 4 |
| C8orf76 | ZNF121 | 0.766319 | 4 | 0 | 4 |
| C8orf76 | CCT8 | 0.760256 | 3 | 0 | 3 |
| C8orf76 | AHCY | 0.759426 | 3 | 0 | 3 |
| C8orf76 | DMTF1 | 0.755618 | 3 | 0 | 3 |
| C8orf76 | NUP50 | 0.755516 | 3 | 0 | 3 |
| C8orf76 | CSNK1G2 | 0.749202 | 4 | 0 | 4 |
| C8orf76 | UNG | 0.747354 | 3 | 0 | 3 |
| C8orf76 | SLC39A9 | 0.744688 | 4 | 0 | 4 |
| C8orf76 | GINS3 | 0.743728 | 4 | 0 | 4 |
| C8orf76 | DCAF13 | 0.74233 | 7 | 0 | 6 |
For details and further investigation, click here
