| Full name: tenascin N | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q25.1 | ||
| Entrez ID: 63923 | HGNC ID: HGNC:22942 | Ensembl Gene: ENSG00000120332 | OMIM ID: 617472 |
| Drug and gene relationship at DGIdb | |||
TNN involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04151 | PI3K-Akt signaling pathway | |
| hsa04510 | Focal adhesion |
Expression of TNN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNN | 63923 | 215271_at | 0.0712 | 0.8218 | |
| GSE20347 | TNN | 63923 | 215271_at | 0.1785 | 0.0230 | |
| GSE23400 | TNN | 63923 | 215271_at | -0.0407 | 0.1283 | |
| GSE26886 | TNN | 63923 | 215271_at | 0.0912 | 0.5982 | |
| GSE29001 | TNN | 63923 | 215271_at | -0.2218 | 0.3488 | |
| GSE38129 | TNN | 63923 | 215271_at | -0.0402 | 0.6961 | |
| GSE45670 | TNN | 63923 | 215271_at | -0.1152 | 0.2862 | |
| GSE53622 | TNN | 63923 | 51533 | 0.3571 | 0.0027 | |
| GSE53624 | TNN | 63923 | 51533 | 0.2791 | 0.0015 | |
| GSE63941 | TNN | 63923 | 215271_at | -0.0071 | 0.9665 | |
| GSE77861 | TNN | 63923 | 215271_at | 0.0291 | 0.7588 | |
| GSE97050 | TNN | 63923 | A_32_P480177 | 0.0762 | 0.7797 | |
| SRP159526 | TNN | 63923 | RNAseq | 0.9543 | 0.2791 | |
| TCGA | TNN | 63923 | RNAseq | 0.0410 | 0.9138 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TNN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNN | 63923 | 11 | 0 | 19 | |
| GSE20123 | TNN | 63923 | 11 | 0 | 19 | |
| GSE43470 | TNN | 63923 | 7 | 2 | 34 | |
| GSE46452 | TNN | 63923 | 3 | 1 | 55 | |
| GSE47630 | TNN | 63923 | 14 | 0 | 26 | |
| GSE54993 | TNN | 63923 | 0 | 6 | 64 | |
| GSE54994 | TNN | 63923 | 15 | 0 | 38 | |
| GSE60625 | TNN | 63923 | 0 | 0 | 11 | |
| GSE74703 | TNN | 63923 | 7 | 2 | 27 | |
| GSE74704 | TNN | 63923 | 5 | 0 | 15 | |
| TCGA | TNN | 63923 | 41 | 3 | 52 |
Total number of gains: 114; Total number of losses: 14; Total Number of normals: 360.
Somatic mutations of TNN:
Generating mutation plots.
Highly correlated genes for TNN:
Showing top 20/272 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNN | TBX21 | 0.749949 | 4 | 0 | 4 |
| TNN | HECW1 | 0.74357 | 5 | 0 | 5 |
| TNN | CDC42EP2 | 0.720072 | 3 | 0 | 3 |
| TNN | C11orf21 | 0.709728 | 3 | 0 | 3 |
| TNN | EFNA2 | 0.709413 | 3 | 0 | 3 |
| TNN | TRPM3 | 0.708479 | 4 | 0 | 3 |
| TNN | OR10C1 | 0.708236 | 4 | 0 | 4 |
| TNN | ZNF444 | 0.702822 | 3 | 0 | 3 |
| TNN | DAB1 | 0.702739 | 4 | 0 | 4 |
| TNN | CNGB3 | 0.696871 | 4 | 0 | 4 |
| TNN | MX2 | 0.695475 | 4 | 0 | 3 |
| TNN | SLC10A1 | 0.694291 | 5 | 0 | 5 |
| TNN | LAT | 0.692073 | 5 | 0 | 4 |
| TNN | HSD3B1 | 0.690647 | 4 | 0 | 4 |
| TNN | UGT3A1 | 0.690409 | 3 | 0 | 3 |
| TNN | CCDC106 | 0.687773 | 4 | 0 | 4 |
| TNN | HPS1 | 0.68717 | 4 | 0 | 4 |
| TNN | AXIN1 | 0.68451 | 3 | 0 | 3 |
| TNN | ATP2B3 | 0.681563 | 4 | 0 | 3 |
| TNN | ATF7IP2 | 0.670093 | 4 | 0 | 3 |
For details and further investigation, click here
