| Full name: chromosome 11 open reading frame 74 | Alias Symbol: FLJ38678|HEPIS|NWC | ||
| Type: protein-coding gene | Cytoband: 11p12 | ||
| Entrez ID: 119710 | HGNC ID: HGNC:25142 | Ensembl Gene: ENSG00000166352 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C11orf74:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C11orf74 | 119710 | 228249_at | -0.4882 | 0.4308 | |
| GSE26886 | C11orf74 | 119710 | 228249_at | 0.6569 | 0.0062 | |
| GSE45670 | C11orf74 | 119710 | 228249_at | -0.2245 | 0.2413 | |
| GSE53622 | C11orf74 | 119710 | 59168 | -0.1251 | 0.2125 | |
| GSE53624 | C11orf74 | 119710 | 59168 | 0.0353 | 0.6938 | |
| GSE63941 | C11orf74 | 119710 | 228249_at | -0.9188 | 0.0388 | |
| GSE77861 | C11orf74 | 119710 | 228249_at | -0.0772 | 0.7418 | |
| GSE97050 | C11orf74 | A_19_P00809992 | -0.1175 | 0.7574 | ||
| SRP007169 | C11orf74 | 119710 | RNAseq | -0.0875 | 0.8525 | |
| SRP008496 | C11orf74 | 119710 | RNAseq | 0.1906 | 0.6392 | |
| SRP064894 | C11orf74 | 119710 | RNAseq | 0.2754 | 0.2545 | |
| SRP133303 | C11orf74 | 119710 | RNAseq | 0.4078 | 0.0966 | |
| SRP159526 | C11orf74 | 119710 | RNAseq | -0.4088 | 0.2144 | |
| SRP193095 | C11orf74 | 119710 | RNAseq | -0.4828 | 0.0008 | |
| SRP219564 | C11orf74 | 119710 | RNAseq | -0.4438 | 0.4265 | |
| TCGA | C11orf74 | 119710 | RNAseq | -0.1981 | 0.0371 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C11orf74 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C11orf74:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C11orf74 | 119710 | 0 | 8 | 22 | |
| GSE20123 | C11orf74 | 119710 | 0 | 7 | 23 | |
| GSE43470 | C11orf74 | 119710 | 3 | 4 | 36 | |
| GSE46452 | C11orf74 | 119710 | 7 | 5 | 47 | |
| GSE47630 | C11orf74 | 119710 | 3 | 10 | 27 | |
| GSE54993 | C11orf74 | 119710 | 3 | 2 | 65 | |
| GSE54994 | C11orf74 | 119710 | 3 | 10 | 40 | |
| GSE60625 | C11orf74 | 119710 | 0 | 0 | 11 | |
| GSE74703 | C11orf74 | 119710 | 2 | 2 | 32 | |
| GSE74704 | C11orf74 | 119710 | 0 | 5 | 15 | |
| TCGA | C11orf74 | 119710 | 12 | 23 | 61 |
Total number of gains: 33; Total number of losses: 76; Total Number of normals: 379.
Somatic mutations of C11orf74:
Generating mutation plots.
Highly correlated genes for C11orf74:
Showing top 20/294 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C11orf74 | TLE1 | 0.764342 | 3 | 0 | 3 |
| C11orf74 | EIF3L | 0.764322 | 3 | 0 | 3 |
| C11orf74 | RIMKLB | 0.73638 | 3 | 0 | 3 |
| C11orf74 | MRPL48 | 0.731954 | 3 | 0 | 3 |
| C11orf74 | FNIP2 | 0.721022 | 3 | 0 | 3 |
| C11orf74 | ZNF358 | 0.690154 | 3 | 0 | 3 |
| C11orf74 | CD59 | 0.689581 | 3 | 0 | 3 |
| C11orf74 | PSME1 | 0.685542 | 3 | 0 | 3 |
| C11orf74 | LITAF | 0.684095 | 3 | 0 | 3 |
| C11orf74 | STXBP3 | 0.684019 | 3 | 0 | 3 |
| C11orf74 | ZBTB26 | 0.681081 | 3 | 0 | 3 |
| C11orf74 | ZNF334 | 0.67965 | 3 | 0 | 3 |
| C11orf74 | NOA1 | 0.673109 | 3 | 0 | 3 |
| C11orf74 | LSM11 | 0.672683 | 4 | 0 | 3 |
| C11orf74 | ITGAM | 0.664015 | 3 | 0 | 3 |
| C11orf74 | RBM27 | 0.659481 | 3 | 0 | 3 |
| C11orf74 | ZNF34 | 0.659073 | 4 | 0 | 4 |
| C11orf74 | TRMT11 | 0.658477 | 3 | 0 | 3 |
| C11orf74 | UBR3 | 0.658083 | 4 | 0 | 3 |
| C11orf74 | DNAJC13 | 0.658037 | 3 | 0 | 3 |
For details and further investigation, click here
