| Full name: tRNA methyltransferase 11 homolog | Alias Symbol: MDS024|dJ187J11.2|TRM11|TRMT11-1 | ||
| Type: protein-coding gene | Cytoband: 6q22.32 | ||
| Entrez ID: 60487 | HGNC ID: HGNC:21080 | Ensembl Gene: ENSG00000066651 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TRMT11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRMT11 | 60487 | 218877_s_at | -0.2037 | 0.5649 | |
| GSE20347 | TRMT11 | 60487 | 218877_s_at | 0.3111 | 0.1082 | |
| GSE23400 | TRMT11 | 60487 | 218877_s_at | 0.4373 | 0.0000 | |
| GSE26886 | TRMT11 | 60487 | 218877_s_at | 0.0991 | 0.8734 | |
| GSE29001 | TRMT11 | 60487 | 218877_s_at | 0.2303 | 0.4037 | |
| GSE38129 | TRMT11 | 60487 | 218877_s_at | 0.3172 | 0.0082 | |
| GSE45670 | TRMT11 | 60487 | 218877_s_at | -0.3455 | 0.0087 | |
| GSE53622 | TRMT11 | 60487 | 44658 | 0.4990 | 0.0000 | |
| GSE53624 | TRMT11 | 60487 | 44658 | 0.3158 | 0.0059 | |
| GSE63941 | TRMT11 | 60487 | 218877_s_at | -0.3687 | 0.7755 | |
| GSE77861 | TRMT11 | 60487 | 218877_s_at | 0.0131 | 0.9781 | |
| GSE97050 | TRMT11 | 60487 | A_24_P89509 | 0.4839 | 0.0970 | |
| SRP007169 | TRMT11 | 60487 | RNAseq | 0.3721 | 0.4480 | |
| SRP008496 | TRMT11 | 60487 | RNAseq | 0.0005 | 0.9986 | |
| SRP064894 | TRMT11 | 60487 | RNAseq | 0.0792 | 0.7889 | |
| SRP133303 | TRMT11 | 60487 | RNAseq | 0.1432 | 0.1853 | |
| SRP159526 | TRMT11 | 60487 | RNAseq | 0.0542 | 0.7982 | |
| SRP193095 | TRMT11 | 60487 | RNAseq | -0.0218 | 0.8616 | |
| SRP219564 | TRMT11 | 60487 | RNAseq | -0.1113 | 0.6911 | |
| TCGA | TRMT11 | 60487 | RNAseq | 0.0270 | 0.6832 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TRMT11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRMT11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRMT11 | 60487 | 1 | 4 | 25 | |
| GSE20123 | TRMT11 | 60487 | 2 | 3 | 25 | |
| GSE43470 | TRMT11 | 60487 | 5 | 0 | 38 | |
| GSE46452 | TRMT11 | 60487 | 2 | 11 | 46 | |
| GSE47630 | TRMT11 | 60487 | 9 | 4 | 27 | |
| GSE54993 | TRMT11 | 60487 | 4 | 2 | 64 | |
| GSE54994 | TRMT11 | 60487 | 8 | 8 | 37 | |
| GSE60625 | TRMT11 | 60487 | 0 | 1 | 10 | |
| GSE74703 | TRMT11 | 60487 | 4 | 0 | 32 | |
| GSE74704 | TRMT11 | 60487 | 0 | 1 | 19 | |
| TCGA | TRMT11 | 60487 | 11 | 19 | 66 |
Total number of gains: 46; Total number of losses: 53; Total Number of normals: 389.
Somatic mutations of TRMT11:
Generating mutation plots.
Highly correlated genes for TRMT11:
Showing top 20/596 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRMT11 | RWDD2B | 0.810528 | 3 | 0 | 3 |
| TRMT11 | SARNP | 0.797333 | 3 | 0 | 3 |
| TRMT11 | AQR | 0.772672 | 3 | 0 | 3 |
| TRMT11 | ZNF91 | 0.74644 | 3 | 0 | 3 |
| TRMT11 | MRPL46 | 0.733351 | 3 | 0 | 3 |
| TRMT11 | PPIL1 | 0.723937 | 3 | 0 | 3 |
| TRMT11 | ZBTB9 | 0.721365 | 3 | 0 | 3 |
| TRMT11 | CEBPG | 0.709793 | 3 | 0 | 3 |
| TRMT11 | AP1AR | 0.709458 | 4 | 0 | 4 |
| TRMT11 | GATAD1 | 0.709219 | 3 | 0 | 3 |
| TRMT11 | PRKRA | 0.706916 | 4 | 0 | 4 |
| TRMT11 | STX16 | 0.705242 | 3 | 0 | 3 |
| TRMT11 | CBLL1 | 0.703412 | 4 | 0 | 3 |
| TRMT11 | ZNF318 | 0.696252 | 5 | 0 | 5 |
| TRMT11 | USP8 | 0.695922 | 4 | 0 | 4 |
| TRMT11 | DDHD1 | 0.692528 | 3 | 0 | 3 |
| TRMT11 | RRAS2 | 0.692496 | 4 | 0 | 4 |
| TRMT11 | SLC30A5 | 0.692384 | 4 | 0 | 3 |
| TRMT11 | CTBP2 | 0.69073 | 3 | 0 | 3 |
| TRMT11 | PIGM | 0.69066 | 3 | 0 | 3 |
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