| Full name: chromosome 12 open reading frame 56 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q14.2 | ||
| Entrez ID: 115749 | HGNC ID: HGNC:26967 | Ensembl Gene: ENSG00000185306 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C12orf56:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C12orf56 | 115749 | 236840_at | 0.3085 | 0.6528 | |
| GSE26886 | C12orf56 | 115749 | 236840_at | 0.6436 | 0.0226 | |
| GSE45670 | C12orf56 | 115749 | 236840_at | 0.4565 | 0.0711 | |
| GSE53622 | C12orf56 | 115749 | 149674 | 0.9256 | 0.0001 | |
| GSE53624 | C12orf56 | 115749 | 149674 | 0.2245 | 0.0946 | |
| GSE63941 | C12orf56 | 115749 | 236840_at | 3.2605 | 0.0049 | |
| GSE77861 | C12orf56 | 115749 | 236840_at | 0.1278 | 0.6582 | |
| GSE97050 | C12orf56 | 115749 | A_32_P158786 | 0.4491 | 0.3488 | |
| SRP007169 | C12orf56 | 115749 | RNAseq | -0.7108 | 0.2443 | |
| SRP008496 | C12orf56 | 115749 | RNAseq | -0.3539 | 0.3551 | |
| SRP064894 | C12orf56 | 115749 | RNAseq | 0.1986 | 0.6159 | |
| SRP133303 | C12orf56 | 115749 | RNAseq | 1.0099 | 0.0536 | |
| SRP159526 | C12orf56 | 115749 | RNAseq | 0.2748 | 0.6043 | |
| TCGA | C12orf56 | 115749 | RNAseq | 2.4226 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by C12orf56 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C12orf56:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C12orf56 | 115749 | 4 | 1 | 25 | |
| GSE20123 | C12orf56 | 115749 | 4 | 1 | 25 | |
| GSE43470 | C12orf56 | 115749 | 5 | 0 | 38 | |
| GSE46452 | C12orf56 | 115749 | 11 | 0 | 48 | |
| GSE47630 | C12orf56 | 115749 | 10 | 2 | 28 | |
| GSE54993 | C12orf56 | 115749 | 0 | 6 | 64 | |
| GSE54994 | C12orf56 | 115749 | 7 | 1 | 45 | |
| GSE60625 | C12orf56 | 115749 | 0 | 0 | 11 | |
| GSE74703 | C12orf56 | 115749 | 5 | 0 | 31 | |
| GSE74704 | C12orf56 | 115749 | 3 | 1 | 16 | |
| TCGA | C12orf56 | 115749 | 19 | 11 | 66 |
Total number of gains: 68; Total number of losses: 23; Total Number of normals: 397.
Somatic mutations of C12orf56:
Generating mutation plots.
Highly correlated genes for C12orf56:
Showing top 20/96 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C12orf56 | CHD7 | 0.65032 | 3 | 0 | 3 |
| C12orf56 | BEX2 | 0.647529 | 3 | 0 | 3 |
| C12orf56 | F11R | 0.619052 | 4 | 0 | 4 |
| C12orf56 | YWHAE | 0.614098 | 4 | 0 | 4 |
| C12orf56 | RDH11 | 0.609346 | 3 | 0 | 3 |
| C12orf56 | STON2 | 0.608595 | 5 | 0 | 4 |
| C12orf56 | ZNF165 | 0.605783 | 3 | 0 | 3 |
| C12orf56 | MND1 | 0.602581 | 3 | 0 | 3 |
| C12orf56 | XXYLT1 | 0.59958 | 4 | 0 | 4 |
| C12orf56 | TMCO6 | 0.594424 | 3 | 0 | 3 |
| C12orf56 | MTMR1 | 0.592575 | 3 | 0 | 3 |
| C12orf56 | EPB41L4B | 0.592328 | 3 | 0 | 3 |
| C12orf56 | DLX5 | 0.589129 | 5 | 0 | 3 |
| C12orf56 | CENPI | 0.588348 | 4 | 0 | 4 |
| C12orf56 | PLEKHG3 | 0.587167 | 5 | 0 | 4 |
| C12orf56 | GINS1 | 0.586965 | 4 | 0 | 3 |
| C12orf56 | ELMO3 | 0.58495 | 4 | 0 | 3 |
| C12orf56 | BLM | 0.584367 | 3 | 0 | 3 |
| C12orf56 | DERL1 | 0.583991 | 3 | 0 | 3 |
| C12orf56 | RMI2 | 0.581545 | 3 | 0 | 3 |
For details and further investigation, click here
