| Full name: meiotic nuclear divisions 1 | Alias Symbol: GAJ | ||
| Type: protein-coding gene | Cytoband: 4q31.3 | ||
| Entrez ID: 84057 | HGNC ID: HGNC:24839 | Ensembl Gene: ENSG00000121211 | OMIM ID: 611422 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MND1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MND1 | 84057 | 223700_at | 1.4330 | 0.0189 | |
| GSE26886 | MND1 | 84057 | 223700_at | 0.6545 | 0.0034 | |
| GSE45670 | MND1 | 84057 | 223700_at | 1.3082 | 0.0000 | |
| GSE53622 | MND1 | 84057 | 24431 | 1.2446 | 0.0000 | |
| GSE53624 | MND1 | 84057 | 24431 | 1.4767 | 0.0000 | |
| GSE63941 | MND1 | 84057 | 223700_at | 3.0724 | 0.0002 | |
| GSE77861 | MND1 | 84057 | 223700_at | 0.3314 | 0.0632 | |
| GSE97050 | MND1 | 84057 | A_23_P133123 | 0.8271 | 0.1983 | |
| SRP007169 | MND1 | 84057 | RNAseq | 1.4192 | 0.0111 | |
| SRP064894 | MND1 | 84057 | RNAseq | 0.9962 | 0.0000 | |
| SRP133303 | MND1 | 84057 | RNAseq | 1.5372 | 0.0000 | |
| SRP159526 | MND1 | 84057 | RNAseq | 1.3181 | 0.0002 | |
| SRP193095 | MND1 | 84057 | RNAseq | 0.8043 | 0.0000 | |
| SRP219564 | MND1 | 84057 | RNAseq | 1.4251 | 0.0129 | |
| TCGA | MND1 | 84057 | RNAseq | 1.8560 | 0.0000 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by MND1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MND1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MND1 | 84057 | 0 | 14 | 16 | |
| GSE20123 | MND1 | 84057 | 0 | 14 | 16 | |
| GSE43470 | MND1 | 84057 | 0 | 13 | 30 | |
| GSE46452 | MND1 | 84057 | 1 | 36 | 22 | |
| GSE47630 | MND1 | 84057 | 0 | 23 | 17 | |
| GSE54993 | MND1 | 84057 | 10 | 0 | 60 | |
| GSE54994 | MND1 | 84057 | 1 | 13 | 39 | |
| GSE60625 | MND1 | 84057 | 0 | 1 | 10 | |
| GSE74703 | MND1 | 84057 | 0 | 11 | 25 | |
| GSE74704 | MND1 | 84057 | 0 | 7 | 13 | |
| TCGA | MND1 | 84057 | 10 | 35 | 51 |
Total number of gains: 22; Total number of losses: 167; Total Number of normals: 299.
Somatic mutations of MND1:
Generating mutation plots.
Highly correlated genes for MND1:
Showing top 20/1726 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MND1 | UBE2T | 0.800881 | 9 | 0 | 9 |
| MND1 | BUB1 | 0.792991 | 9 | 0 | 9 |
| MND1 | KIF18A | 0.785798 | 9 | 0 | 8 |
| MND1 | RAD51AP1 | 0.783659 | 9 | 0 | 9 |
| MND1 | SPAG5 | 0.775263 | 9 | 0 | 9 |
| MND1 | NCAPH | 0.774906 | 5 | 0 | 5 |
| MND1 | CCNB2 | 0.774771 | 8 | 0 | 7 |
| MND1 | TIMELESS | 0.773704 | 9 | 0 | 8 |
| MND1 | BIRC5 | 0.769818 | 8 | 0 | 7 |
| MND1 | MMS22L | 0.768522 | 3 | 0 | 3 |
| MND1 | UCK2 | 0.767323 | 3 | 0 | 3 |
| MND1 | CENPW | 0.767228 | 8 | 0 | 8 |
| MND1 | GINS1 | 0.76713 | 8 | 0 | 8 |
| MND1 | KIFC1 | 0.765922 | 7 | 0 | 7 |
| MND1 | UBE2C | 0.765233 | 9 | 0 | 9 |
| MND1 | KNSTRN | 0.759212 | 7 | 0 | 7 |
| MND1 | PLK1 | 0.756105 | 7 | 0 | 7 |
| MND1 | CDCA3 | 0.751129 | 9 | 0 | 9 |
| MND1 | NEK2 | 0.750942 | 9 | 0 | 9 |
| MND1 | TPX2 | 0.750869 | 9 | 0 | 8 |
For details and further investigation, click here
