| Full name: distal-less homeobox 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q21.3 | ||
| Entrez ID: 1749 | HGNC ID: HGNC:2918 | Ensembl Gene: ENSG00000105880 | OMIM ID: 600028 |
| Drug and gene relationship at DGIdb | |||
Expression of DLX5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DLX5 | 1749 | 213707_s_at | 1.0353 | 0.3525 | |
| GSE20347 | DLX5 | 1749 | 213707_s_at | 0.7020 | 0.0060 | |
| GSE23400 | DLX5 | 1749 | 213707_s_at | 0.5992 | 0.0000 | |
| GSE26886 | DLX5 | 1749 | 213707_s_at | 1.2348 | 0.0001 | |
| GSE29001 | DLX5 | 1749 | 213707_s_at | 0.4524 | 0.1415 | |
| GSE38129 | DLX5 | 1749 | 213707_s_at | 0.8920 | 0.0002 | |
| GSE45670 | DLX5 | 1749 | 213707_s_at | 1.3201 | 0.0014 | |
| GSE53622 | DLX5 | 1749 | 130082 | 2.0142 | 0.0000 | |
| GSE53624 | DLX5 | 1749 | 130082 | 1.4235 | 0.0000 | |
| GSE63941 | DLX5 | 1749 | 213707_s_at | 1.9415 | 0.1223 | |
| GSE77861 | DLX5 | 1749 | 213707_s_at | 1.2741 | 0.0073 | |
| GSE97050 | DLX5 | 1749 | A_33_P3235147 | 0.5723 | 0.1655 | |
| SRP007169 | DLX5 | 1749 | RNAseq | 0.1933 | 0.6789 | |
| SRP008496 | DLX5 | 1749 | RNAseq | 0.5334 | 0.1908 | |
| SRP064894 | DLX5 | 1749 | RNAseq | 1.9439 | 0.0000 | |
| SRP133303 | DLX5 | 1749 | RNAseq | 2.0777 | 0.0000 | |
| SRP159526 | DLX5 | 1749 | RNAseq | 3.0541 | 0.0000 | |
| SRP219564 | DLX5 | 1749 | RNAseq | 1.5261 | 0.0321 | |
| TCGA | DLX5 | 1749 | RNAseq | 2.0740 | 0.0000 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by DLX5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DLX5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DLX5 | 1749 | 13 | 0 | 17 | |
| GSE20123 | DLX5 | 1749 | 13 | 0 | 17 | |
| GSE43470 | DLX5 | 1749 | 8 | 1 | 34 | |
| GSE46452 | DLX5 | 1749 | 12 | 0 | 47 | |
| GSE47630 | DLX5 | 1749 | 9 | 2 | 29 | |
| GSE54993 | DLX5 | 1749 | 1 | 9 | 60 | |
| GSE54994 | DLX5 | 1749 | 16 | 3 | 34 | |
| GSE60625 | DLX5 | 1749 | 0 | 5 | 6 | |
| GSE74703 | DLX5 | 1749 | 7 | 1 | 28 | |
| GSE74704 | DLX5 | 1749 | 9 | 0 | 11 | |
| TCGA | DLX5 | 1749 | 53 | 5 | 38 |
Total number of gains: 141; Total number of losses: 26; Total Number of normals: 321.
Somatic mutations of DLX5:
Generating mutation plots.
Highly correlated genes for DLX5:
Showing top 20/914 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DLX5 | NEIL2 | 0.74759 | 3 | 0 | 3 |
| DLX5 | DLX6-AS1 | 0.746485 | 5 | 0 | 5 |
| DLX5 | PTPMT1 | 0.720991 | 3 | 0 | 3 |
| DLX5 | SERPINA9 | 0.699963 | 3 | 0 | 3 |
| DLX5 | TACO1 | 0.697206 | 4 | 0 | 4 |
| DLX5 | INO80B | 0.696147 | 3 | 0 | 3 |
| DLX5 | B4GALNT3 | 0.688529 | 7 | 0 | 6 |
| DLX5 | ID1 | 0.686859 | 3 | 0 | 3 |
| DLX5 | PGBD5 | 0.683602 | 11 | 0 | 10 |
| DLX5 | FABP4 | 0.679934 | 4 | 0 | 3 |
| DLX5 | FOXE1 | 0.675971 | 12 | 0 | 11 |
| DLX5 | C2orf69 | 0.672545 | 4 | 0 | 4 |
| DLX5 | SLC4A2 | 0.6699 | 3 | 0 | 3 |
| DLX5 | LRRC58 | 0.66858 | 4 | 0 | 3 |
| DLX5 | SLC39A3 | 0.663951 | 3 | 0 | 3 |
| DLX5 | KRTDAP | 0.660463 | 7 | 0 | 6 |
| DLX5 | C1orf226 | 0.657914 | 5 | 0 | 5 |
| DLX5 | NGF | 0.654758 | 3 | 0 | 3 |
| DLX5 | SLC7A8 | 0.648034 | 12 | 0 | 10 |
| DLX5 | CASC15 | 0.647422 | 4 | 0 | 3 |
For details and further investigation, click here
