| Full name: retinol dehydrogenase 11 | Alias Symbol: MDT1|SDR7C1|ARSDR1 | ||
| Type: protein-coding gene | Cytoband: 14q24.1 | ||
| Entrez ID: 51109 | HGNC ID: HGNC:17964 | Ensembl Gene: ENSG00000072042 | OMIM ID: 607849 |
| Drug and gene relationship at DGIdb | |||
Expression of RDH11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RDH11 | 51109 | 217776_at | -0.0601 | 0.9581 | |
| GSE20347 | RDH11 | 51109 | 217776_at | 0.3409 | 0.0762 | |
| GSE23400 | RDH11 | 51109 | 217776_at | 0.4235 | 0.0000 | |
| GSE26886 | RDH11 | 51109 | 217776_at | 0.2445 | 0.2233 | |
| GSE29001 | RDH11 | 51109 | 217776_at | 0.3640 | 0.2593 | |
| GSE38129 | RDH11 | 51109 | 217776_at | 0.3785 | 0.0032 | |
| GSE45670 | RDH11 | 51109 | 217776_at | 0.5800 | 0.0001 | |
| GSE53622 | RDH11 | 51109 | 105017 | 0.4408 | 0.0000 | |
| GSE53624 | RDH11 | 51109 | 105017 | 0.5938 | 0.0000 | |
| GSE63941 | RDH11 | 51109 | 217776_at | 0.0412 | 0.9332 | |
| GSE77861 | RDH11 | 51109 | 217776_at | 0.1792 | 0.6536 | |
| GSE97050 | RDH11 | 51109 | A_23_P25684 | 0.4933 | 0.2179 | |
| SRP007169 | RDH11 | 51109 | RNAseq | 0.2512 | 0.4276 | |
| SRP008496 | RDH11 | 51109 | RNAseq | 0.2451 | 0.3434 | |
| SRP064894 | RDH11 | 51109 | RNAseq | 0.4865 | 0.0004 | |
| SRP133303 | RDH11 | 51109 | RNAseq | 0.6504 | 0.0003 | |
| SRP159526 | RDH11 | 51109 | RNAseq | 0.2249 | 0.4887 | |
| SRP193095 | RDH11 | 51109 | RNAseq | 0.2003 | 0.1392 | |
| SRP219564 | RDH11 | 51109 | RNAseq | 0.2524 | 0.4478 | |
| TCGA | RDH11 | 51109 | RNAseq | 0.0634 | 0.1839 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RDH11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RDH11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RDH11 | 51109 | 7 | 2 | 21 | |
| GSE20123 | RDH11 | 51109 | 7 | 2 | 21 | |
| GSE43470 | RDH11 | 51109 | 8 | 2 | 33 | |
| GSE46452 | RDH11 | 51109 | 16 | 3 | 40 | |
| GSE47630 | RDH11 | 51109 | 11 | 9 | 20 | |
| GSE54993 | RDH11 | 51109 | 3 | 9 | 58 | |
| GSE54994 | RDH11 | 51109 | 18 | 5 | 30 | |
| GSE60625 | RDH11 | 51109 | 0 | 2 | 9 | |
| GSE74703 | RDH11 | 51109 | 7 | 2 | 27 | |
| GSE74704 | RDH11 | 51109 | 3 | 2 | 15 | |
| TCGA | RDH11 | 51109 | 33 | 15 | 48 |
Total number of gains: 113; Total number of losses: 53; Total Number of normals: 322.
Somatic mutations of RDH11:
Generating mutation plots.
Highly correlated genes for RDH11:
Showing top 20/645 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RDH11 | TRAPPC6B | 0.759809 | 3 | 0 | 3 |
| RDH11 | ELOVL7 | 0.727936 | 3 | 0 | 3 |
| RDH11 | TMEM167A | 0.725649 | 4 | 0 | 4 |
| RDH11 | JKAMP | 0.719792 | 7 | 0 | 7 |
| RDH11 | TTC4 | 0.712657 | 5 | 0 | 5 |
| RDH11 | MED10 | 0.697609 | 3 | 0 | 3 |
| RDH11 | PTP4A1 | 0.689705 | 4 | 0 | 4 |
| RDH11 | ANGPTL4 | 0.689515 | 3 | 0 | 3 |
| RDH11 | CCNK | 0.689236 | 8 | 0 | 7 |
| RDH11 | AASDHPPT | 0.688007 | 3 | 0 | 3 |
| RDH11 | TMED10 | 0.687538 | 5 | 0 | 4 |
| RDH11 | COX16 | 0.685523 | 5 | 0 | 4 |
| RDH11 | KRTDAP | 0.682392 | 4 | 0 | 4 |
| RDH11 | GTF2H3 | 0.677587 | 4 | 0 | 3 |
| RDH11 | SCAMP1 | 0.67627 | 5 | 0 | 4 |
| RDH11 | ISCA2 | 0.674904 | 8 | 0 | 6 |
| RDH11 | SNW1 | 0.673023 | 11 | 0 | 10 |
| RDH11 | GINS4 | 0.672479 | 3 | 0 | 3 |
| RDH11 | CDC27 | 0.666783 | 3 | 0 | 3 |
| RDH11 | C14orf119 | 0.666774 | 4 | 0 | 3 |
For details and further investigation, click here
