| Full name: centromere protein I | Alias Symbol: LRPR1|CENP-I|Mis6 | ||
| Type: protein-coding gene | Cytoband: Xq22.1 | ||
| Entrez ID: 2491 | HGNC ID: HGNC:3968 | Ensembl Gene: ENSG00000102384 | OMIM ID: 300065 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CENPI:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CENPI | 2491 | 214804_at | 1.4410 | 0.0250 | |
| GSE20347 | CENPI | 2491 | 214804_at | 1.2403 | 0.0000 | |
| GSE23400 | CENPI | 2491 | 214804_at | 0.4838 | 0.0000 | |
| GSE26886 | CENPI | 2491 | 214804_at | 1.2009 | 0.0012 | |
| GSE29001 | CENPI | 2491 | 214804_at | 1.3817 | 0.0013 | |
| GSE38129 | CENPI | 2491 | 214804_at | 1.2255 | 0.0000 | |
| GSE45670 | CENPI | 2491 | 214804_at | 1.3121 | 0.0000 | |
| GSE53622 | CENPI | 2491 | 61476 | 1.7454 | 0.0000 | |
| GSE53624 | CENPI | 2491 | 61476 | 1.1828 | 0.0000 | |
| GSE63941 | CENPI | 2491 | 207590_s_at | 1.7436 | 0.0047 | |
| GSE77861 | CENPI | 2491 | 214804_at | 0.3342 | 0.0198 | |
| GSE97050 | CENPI | 2491 | A_33_P3221313 | 1.1890 | 0.1189 | |
| SRP007169 | CENPI | 2491 | RNAseq | 2.2371 | 0.0001 | |
| SRP008496 | CENPI | 2491 | RNAseq | 1.5683 | 0.0005 | |
| SRP064894 | CENPI | 2491 | RNAseq | 1.6217 | 0.0000 | |
| SRP133303 | CENPI | 2491 | RNAseq | 2.0783 | 0.0000 | |
| SRP159526 | CENPI | 2491 | RNAseq | 1.2998 | 0.0004 | |
| SRP193095 | CENPI | 2491 | RNAseq | 1.1924 | 0.0000 | |
| SRP219564 | CENPI | 2491 | RNAseq | 1.7982 | 0.0071 | |
| TCGA | CENPI | 2491 | RNAseq | 1.5262 | 0.0000 |
Upregulated datasets: 17; Downregulated datasets: 0.
Survival by CENPI expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CENPI:
No record found for this gene.
Somatic mutations of CENPI:
Generating mutation plots.
Highly correlated genes for CENPI:
Showing top 20/1835 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CENPI | NUF2 | 0.818599 | 8 | 0 | 8 |
| CENPI | HJURP | 0.806333 | 12 | 0 | 12 |
| CENPI | TPX2 | 0.800216 | 12 | 0 | 12 |
| CENPI | KIF20A | 0.80001 | 12 | 0 | 12 |
| CENPI | TOP2A | 0.798651 | 12 | 0 | 12 |
| CENPI | AURKA | 0.798644 | 12 | 0 | 12 |
| CENPI | STIL | 0.796996 | 12 | 0 | 11 |
| CENPI | UHRF1 | 0.791142 | 8 | 0 | 8 |
| CENPI | BUB1 | 0.790587 | 10 | 0 | 10 |
| CENPI | KIF14 | 0.789543 | 12 | 0 | 12 |
| CENPI | UBE2C | 0.788975 | 12 | 0 | 12 |
| CENPI | MYBL2 | 0.787355 | 12 | 0 | 12 |
| CENPI | CENPF | 0.787065 | 12 | 0 | 12 |
| CENPI | FOXD2 | 0.78572 | 3 | 0 | 3 |
| CENPI | CDC20 | 0.783763 | 11 | 0 | 11 |
| CENPI | SPAG5 | 0.781686 | 12 | 0 | 11 |
| CENPI | KNTC1 | 0.78003 | 12 | 0 | 11 |
| CENPI | WDHD1 | 0.778884 | 12 | 0 | 12 |
| CENPI | CEP55 | 0.77838 | 12 | 0 | 12 |
| CENPI | TRIP13 | 0.777468 | 12 | 0 | 11 |
For details and further investigation, click here
