| Full name: neuraminidase 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.5 | ||
| Entrez ID: 10825 | HGNC ID: HGNC:7760 | Ensembl Gene: ENSG00000162139 | OMIM ID: 604617 |
| Drug and gene relationship at DGIdb | |||
Expression of NEU3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEU3 | 10825 | 235474_at | 0.6866 | 0.2492 | |
| GSE20347 | NEU3 | 10825 | 216083_s_at | -0.0550 | 0.6148 | |
| GSE23400 | NEU3 | 10825 | 206948_at | -0.1337 | 0.0003 | |
| GSE26886 | NEU3 | 10825 | 235474_at | 0.7454 | 0.0001 | |
| GSE29001 | NEU3 | 10825 | 206948_at | -0.0402 | 0.8267 | |
| GSE38129 | NEU3 | 10825 | 216083_s_at | -0.1700 | 0.0821 | |
| GSE45670 | NEU3 | 10825 | 235474_at | 0.2774 | 0.0319 | |
| GSE53622 | NEU3 | 10825 | 15014 | 0.6380 | 0.0000 | |
| GSE53624 | NEU3 | 10825 | 37474 | 0.9309 | 0.0000 | |
| GSE63941 | NEU3 | 10825 | 235474_at | 0.4900 | 0.3317 | |
| GSE77861 | NEU3 | 10825 | 235474_at | 0.0668 | 0.7573 | |
| GSE97050 | NEU3 | 10825 | A_23_P203716 | 0.4800 | 0.3073 | |
| SRP007169 | NEU3 | 10825 | RNAseq | 1.7441 | 0.0015 | |
| SRP008496 | NEU3 | 10825 | RNAseq | 2.4004 | 0.0000 | |
| SRP064894 | NEU3 | 10825 | RNAseq | 0.4207 | 0.0154 | |
| SRP133303 | NEU3 | 10825 | RNAseq | -0.2273 | 0.1921 | |
| SRP159526 | NEU3 | 10825 | RNAseq | -0.0588 | 0.8259 | |
| SRP193095 | NEU3 | 10825 | RNAseq | 0.3286 | 0.0381 | |
| SRP219564 | NEU3 | 10825 | RNAseq | 0.5666 | 0.2812 | |
| TCGA | NEU3 | 10825 | RNAseq | -0.2456 | 0.0327 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NEU3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NEU3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEU3 | 10825 | 6 | 8 | 16 | |
| GSE20123 | NEU3 | 10825 | 6 | 7 | 17 | |
| GSE43470 | NEU3 | 10825 | 5 | 4 | 34 | |
| GSE46452 | NEU3 | 10825 | 7 | 22 | 30 | |
| GSE47630 | NEU3 | 10825 | 6 | 14 | 20 | |
| GSE54993 | NEU3 | 10825 | 8 | 2 | 60 | |
| GSE54994 | NEU3 | 10825 | 8 | 15 | 30 | |
| GSE60625 | NEU3 | 10825 | 4 | 3 | 4 | |
| GSE74703 | NEU3 | 10825 | 4 | 3 | 29 | |
| GSE74704 | NEU3 | 10825 | 4 | 3 | 13 | |
| TCGA | NEU3 | 10825 | 22 | 33 | 41 |
Total number of gains: 80; Total number of losses: 114; Total Number of normals: 294.
Somatic mutations of NEU3:
Generating mutation plots.
Highly correlated genes for NEU3:
Showing top 20/836 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEU3 | P2RX6 | 0.761533 | 4 | 0 | 4 |
| NEU3 | JAK3 | 0.742608 | 5 | 0 | 5 |
| NEU3 | C1orf68 | 0.736702 | 3 | 0 | 3 |
| NEU3 | DPP9 | 0.735602 | 3 | 0 | 3 |
| NEU3 | CHRM5 | 0.735179 | 4 | 0 | 4 |
| NEU3 | GAS6 | 0.731816 | 3 | 0 | 3 |
| NEU3 | CLDN18 | 0.731373 | 3 | 0 | 3 |
| NEU3 | ADAM22 | 0.730908 | 5 | 0 | 5 |
| NEU3 | ACBD6 | 0.728481 | 4 | 0 | 4 |
| NEU3 | DPF3 | 0.724309 | 4 | 0 | 4 |
| NEU3 | SLC35B2 | 0.719991 | 3 | 0 | 3 |
| NEU3 | C19orf54 | 0.717251 | 3 | 0 | 3 |
| NEU3 | FAM90A1 | 0.716591 | 3 | 0 | 3 |
| NEU3 | INTS4 | 0.715796 | 8 | 0 | 7 |
| NEU3 | BMP15 | 0.714426 | 5 | 0 | 5 |
| NEU3 | CYP1A2 | 0.714413 | 5 | 0 | 5 |
| NEU3 | C12orf66 | 0.710649 | 3 | 0 | 3 |
| NEU3 | ZNF275 | 0.709231 | 4 | 0 | 4 |
| NEU3 | DGKQ | 0.708722 | 3 | 0 | 3 |
| NEU3 | MRPL36 | 0.708365 | 4 | 0 | 4 |
For details and further investigation, click here
