| Full name: chromosome 3 open reading frame 14 | Alias Symbol: HT021 | ||
| Type: protein-coding gene | Cytoband: 3p14.2 | ||
| Entrez ID: 57415 | HGNC ID: HGNC:25024 | Ensembl Gene: ENSG00000114405 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C3orf14:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C3orf14 | 57415 | 219288_at | 0.2245 | 0.7818 | |
| GSE20347 | C3orf14 | 57415 | 219288_at | -1.4627 | 0.0056 | |
| GSE23400 | C3orf14 | 57415 | 219288_at | -0.5590 | 0.0000 | |
| GSE26886 | C3orf14 | 57415 | 219288_at | -1.1914 | 0.0974 | |
| GSE29001 | C3orf14 | 57415 | 219288_at | -1.9239 | 0.0043 | |
| GSE38129 | C3orf14 | 57415 | 219288_at | -1.1509 | 0.0043 | |
| GSE45670 | C3orf14 | 57415 | 219288_at | -0.5060 | 0.3266 | |
| GSE53622 | C3orf14 | 57415 | 71426 | -0.9107 | 0.0000 | |
| GSE53624 | C3orf14 | 57415 | 71426 | -1.1997 | 0.0000 | |
| GSE63941 | C3orf14 | 57415 | 219288_at | -2.0414 | 0.3494 | |
| GSE77861 | C3orf14 | 57415 | 219288_at | -1.1009 | 0.1587 | |
| GSE97050 | C3orf14 | 57415 | A_23_P29655 | 0.2206 | 0.3987 | |
| SRP007169 | C3orf14 | 57415 | RNAseq | -1.1904 | 0.0077 | |
| SRP064894 | C3orf14 | 57415 | RNAseq | -0.6803 | 0.0280 | |
| SRP133303 | C3orf14 | 57415 | RNAseq | -0.7318 | 0.0449 | |
| SRP159526 | C3orf14 | 57415 | RNAseq | -1.4792 | 0.0081 | |
| SRP193095 | C3orf14 | 57415 | RNAseq | -1.1690 | 0.0001 | |
| SRP219564 | C3orf14 | 57415 | RNAseq | -0.6234 | 0.3517 | |
| TCGA | C3orf14 | 57415 | RNAseq | 0.3264 | 0.2037 |
Upregulated datasets: 0; Downregulated datasets: 7.
Survival by C3orf14 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C3orf14:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C3orf14 | 57415 | 0 | 18 | 12 | |
| GSE20123 | C3orf14 | 57415 | 0 | 18 | 12 | |
| GSE43470 | C3orf14 | 57415 | 0 | 19 | 24 | |
| GSE46452 | C3orf14 | 57415 | 2 | 17 | 40 | |
| GSE47630 | C3orf14 | 57415 | 1 | 24 | 15 | |
| GSE54993 | C3orf14 | 57415 | 5 | 2 | 63 | |
| GSE54994 | C3orf14 | 57415 | 1 | 32 | 20 | |
| GSE60625 | C3orf14 | 57415 | 3 | 1 | 7 | |
| GSE74703 | C3orf14 | 57415 | 0 | 16 | 20 | |
| GSE74704 | C3orf14 | 57415 | 0 | 12 | 8 | |
| TCGA | C3orf14 | 57415 | 0 | 78 | 18 |
Total number of gains: 12; Total number of losses: 237; Total Number of normals: 239.
Somatic mutations of C3orf14:
Generating mutation plots.
Highly correlated genes for C3orf14:
Showing top 20/134 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C3orf14 | ZNF789 | 0.719013 | 3 | 0 | 3 |
| C3orf14 | FNBP1L | 0.707591 | 3 | 0 | 3 |
| C3orf14 | C1orf174 | 0.691888 | 3 | 0 | 3 |
| C3orf14 | WWP1 | 0.68627 | 3 | 0 | 3 |
| C3orf14 | FBXO6 | 0.67811 | 3 | 0 | 3 |
| C3orf14 | RDH10 | 0.676627 | 3 | 0 | 3 |
| C3orf14 | ZNF320 | 0.657967 | 3 | 0 | 3 |
| C3orf14 | SLC35B3 | 0.639939 | 3 | 0 | 3 |
| C3orf14 | HYLS1 | 0.639124 | 3 | 0 | 3 |
| C3orf14 | SENP6 | 0.638066 | 3 | 0 | 3 |
| C3orf14 | AGMAT | 0.631751 | 3 | 0 | 3 |
| C3orf14 | ZFP30 | 0.626174 | 4 | 0 | 3 |
| C3orf14 | TRMT13 | 0.625318 | 3 | 0 | 3 |
| C3orf14 | IFNAR1 | 0.625101 | 3 | 0 | 3 |
| C3orf14 | HECTD3 | 0.620928 | 4 | 0 | 4 |
| C3orf14 | ZNF586 | 0.620802 | 5 | 0 | 4 |
| C3orf14 | BIVM | 0.619459 | 4 | 0 | 3 |
| C3orf14 | NBPF1 | 0.617852 | 3 | 0 | 3 |
| C3orf14 | TMEM126B | 0.611092 | 4 | 0 | 3 |
| C3orf14 | INPP5D | 0.609734 | 4 | 0 | 4 |
For details and further investigation, click here
