| Full name: retinol dehydrogenase 10 | Alias Symbol: SDR16C4 | ||
| Type: protein-coding gene | Cytoband: 8q21.11 | ||
| Entrez ID: 157506 | HGNC ID: HGNC:19975 | Ensembl Gene: ENSG00000121039 | OMIM ID: 607599 |
| Drug and gene relationship at DGIdb | |||
Expression of RDH10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RDH10 | 157506 | 226021_at | 1.0657 | 0.3277 | |
| GSE26886 | RDH10 | 157506 | 226021_at | 0.1543 | 0.8718 | |
| GSE45670 | RDH10 | 157506 | 226021_at | 1.6467 | 0.0000 | |
| GSE53622 | RDH10 | 157506 | 38844 | 0.7060 | 0.0000 | |
| GSE53624 | RDH10 | 157506 | 38844 | 0.7661 | 0.0000 | |
| GSE63941 | RDH10 | 157506 | 226021_at | -2.3497 | 0.0595 | |
| GSE77861 | RDH10 | 157506 | 226021_at | 1.0339 | 0.1261 | |
| GSE97050 | RDH10 | 157506 | A_32_P25050 | 0.9229 | 0.3813 | |
| SRP007169 | RDH10 | 157506 | RNAseq | 1.8498 | 0.0000 | |
| SRP008496 | RDH10 | 157506 | RNAseq | 0.7895 | 0.0968 | |
| SRP064894 | RDH10 | 157506 | RNAseq | 1.1306 | 0.0033 | |
| SRP133303 | RDH10 | 157506 | RNAseq | 1.2894 | 0.0019 | |
| SRP159526 | RDH10 | 157506 | RNAseq | 1.0890 | 0.0195 | |
| SRP193095 | RDH10 | 157506 | RNAseq | 0.6561 | 0.0788 | |
| SRP219564 | RDH10 | 157506 | RNAseq | 0.8874 | 0.0425 | |
| TCGA | RDH10 | 157506 | RNAseq | -0.0617 | 0.5385 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by RDH10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RDH10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RDH10 | 157506 | 15 | 0 | 15 | |
| GSE20123 | RDH10 | 157506 | 16 | 0 | 14 | |
| GSE43470 | RDH10 | 157506 | 18 | 1 | 24 | |
| GSE46452 | RDH10 | 157506 | 21 | 1 | 37 | |
| GSE47630 | RDH10 | 157506 | 23 | 0 | 17 | |
| GSE54993 | RDH10 | 157506 | 0 | 19 | 51 | |
| GSE54994 | RDH10 | 157506 | 30 | 0 | 23 | |
| GSE60625 | RDH10 | 157506 | 0 | 4 | 7 | |
| GSE74703 | RDH10 | 157506 | 15 | 1 | 20 | |
| GSE74704 | RDH10 | 157506 | 11 | 0 | 9 | |
| TCGA | RDH10 | 157506 | 50 | 2 | 44 |
Total number of gains: 199; Total number of losses: 28; Total Number of normals: 261.
Somatic mutations of RDH10:
Generating mutation plots.
Highly correlated genes for RDH10:
Showing top 20/321 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RDH10 | SRSF6 | 0.743612 | 3 | 0 | 3 |
| RDH10 | ZFYVE27 | 0.70758 | 3 | 0 | 3 |
| RDH10 | POLA1 | 0.688124 | 3 | 0 | 3 |
| RDH10 | CHD4 | 0.683956 | 3 | 0 | 3 |
| RDH10 | ARHGAP24 | 0.683729 | 3 | 0 | 3 |
| RDH10 | FOXP4 | 0.681505 | 3 | 0 | 3 |
| RDH10 | C3orf14 | 0.676627 | 3 | 0 | 3 |
| RDH10 | TULP4 | 0.674043 | 3 | 0 | 3 |
| RDH10 | MRPL18 | 0.672691 | 3 | 0 | 3 |
| RDH10 | RALGAPA2 | 0.671618 | 3 | 0 | 3 |
| RDH10 | TMTC4 | 0.669691 | 3 | 0 | 3 |
| RDH10 | CCNT1 | 0.664605 | 3 | 0 | 3 |
| RDH10 | KRR1 | 0.6632 | 3 | 0 | 3 |
| RDH10 | GSK3B | 0.660408 | 3 | 0 | 3 |
| RDH10 | SENP1 | 0.659059 | 3 | 0 | 3 |
| RDH10 | ARHGAP23 | 0.657283 | 3 | 0 | 3 |
| RDH10 | DDX23 | 0.651059 | 4 | 0 | 3 |
| RDH10 | MIS18A | 0.650668 | 3 | 0 | 3 |
| RDH10 | NOM1 | 0.649695 | 3 | 0 | 3 |
| RDH10 | MPHOSPH6 | 0.649496 | 3 | 0 | 3 |
For details and further investigation, click here
