| Full name: KRAB box domain containing 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p22.1 | ||
| Entrez ID: 100506243 | HGNC ID: HGNC:38708 | Ensembl Gene: ENSG00000240747 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of KRBOX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRBOX1 | 100506243 | 228721_at | -0.7737 | 0.0739 | |
| GSE26886 | KRBOX1 | 100506243 | 228721_at | -0.3936 | 0.1993 | |
| GSE45670 | KRBOX1 | 100506243 | 228721_at | -0.0458 | 0.8974 | |
| GSE53622 | KRBOX1 | 100506243 | 116227 | -0.1162 | 0.5283 | |
| GSE53624 | KRBOX1 | 100506243 | 116227 | -0.6287 | 0.0001 | |
| GSE63941 | KRBOX1 | 100506243 | 228721_at | -1.9642 | 0.0559 | |
| GSE77861 | KRBOX1 | 100506243 | 228721_at | -0.1134 | 0.4471 | |
| GSE97050 | KRBOX1 | 100506243 | A_23_P80551 | -0.4132 | 0.3087 | |
| SRP064894 | KRBOX1 | 100506243 | RNAseq | -0.9759 | 0.0019 | |
| SRP133303 | KRBOX1 | 100506243 | RNAseq | -1.6268 | 0.0012 | |
| SRP219564 | KRBOX1 | 100506243 | RNAseq | -0.3257 | 0.7139 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by KRBOX1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of KRBOX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRBOX1 | 100506243 | 0 | 19 | 11 | |
| GSE20123 | KRBOX1 | 100506243 | 0 | 19 | 11 | |
| GSE43470 | KRBOX1 | 100506243 | 0 | 20 | 23 | |
| GSE46452 | KRBOX1 | 100506243 | 2 | 17 | 40 | |
| GSE47630 | KRBOX1 | 100506243 | 1 | 24 | 15 | |
| GSE54993 | KRBOX1 | 100506243 | 7 | 2 | 61 | |
| GSE54994 | KRBOX1 | 100506243 | 1 | 34 | 18 | |
| GSE60625 | KRBOX1 | 100506243 | 5 | 0 | 6 | |
| GSE74703 | KRBOX1 | 100506243 | 0 | 16 | 20 | |
| GSE74704 | KRBOX1 | 100506243 | 0 | 13 | 7 | |
| TCGA | KRBOX1 | 100506243 | 1 | 71 | 24 |
Total number of gains: 17; Total number of losses: 235; Total Number of normals: 236.
Somatic mutations of KRBOX1:
Generating mutation plots.
Highly correlated genes for KRBOX1:
Showing top 20/30 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRBOX1 | ZNF454 | 0.721526 | 3 | 0 | 3 |
| KRBOX1 | ANKRD33 | 0.720197 | 3 | 0 | 3 |
| KRBOX1 | SERPINA11 | 0.713153 | 3 | 0 | 3 |
| KRBOX1 | NBEA | 0.679656 | 4 | 0 | 3 |
| KRBOX1 | DCAF8L2 | 0.654639 | 3 | 0 | 3 |
| KRBOX1 | FAM110B | 0.650078 | 3 | 0 | 3 |
| KRBOX1 | BEST4 | 0.646654 | 3 | 0 | 3 |
| KRBOX1 | GAB2 | 0.640288 | 4 | 0 | 4 |
| KRBOX1 | PDZRN3 | 0.6337 | 4 | 0 | 3 |
| KRBOX1 | C3orf35 | 0.632965 | 3 | 0 | 3 |
| KRBOX1 | KLHL10 | 0.629855 | 3 | 0 | 3 |
| KRBOX1 | HACE1 | 0.617975 | 4 | 0 | 3 |
| KRBOX1 | ZDHHC15 | 0.615336 | 5 | 0 | 3 |
| KRBOX1 | ZNF568 | 0.59592 | 5 | 0 | 4 |
| KRBOX1 | BCL2L15 | 0.59285 | 4 | 0 | 3 |
| KRBOX1 | PRKCB | 0.591126 | 4 | 0 | 3 |
| KRBOX1 | P2RY14 | 0.5748 | 4 | 0 | 3 |
| KRBOX1 | PRPF18 | 0.574364 | 3 | 0 | 3 |
| KRBOX1 | KIT | 0.565014 | 3 | 0 | 3 |
| KRBOX1 | SOX6 | 0.563858 | 3 | 0 | 3 |
For details and further investigation, click here
