BCL2L15

 

Full name: BCL2 like 15 Alias Symbol: Bfk|FLJ22588
Type: protein-coding gene Cytoband: 1p13.2
Entrez ID: 440603 HGNC ID: HGNC:33624 Ensembl Gene: ENSG00000188761 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of BCL2L15:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BCL2L15 440603 236979_at -0.5113 0.1223
GSE26886 BCL2L15 440603 236979_at -0.7780 0.0005
GSE45670 BCL2L15 440603 236979_at -0.0002 0.9994
GSE53622 BCL2L15 440603 110962 -2.0239 0.0000
GSE53624 BCL2L15 440603 110962 -2.8486 0.0000
GSE63941 BCL2L15 440603 236979_at 0.1286 0.8381
GSE77861 BCL2L15 440603 236979_at -0.3922 0.0064
GSE97050 BCL2L15 440603 A_33_P3408177 -0.1609 0.4555
SRP007169 BCL2L15 440603 RNAseq -1.2849 0.0266
SRP064894 BCL2L15 440603 RNAseq -1.6515 0.0000
SRP133303 BCL2L15 440603 RNAseq -1.0899 0.0002
SRP159526 BCL2L15 440603 RNAseq -3.7371 0.0000
SRP193095 BCL2L15 440603 RNAseq -1.6287 0.0011
SRP219564 BCL2L15 440603 RNAseq -1.9930 0.0048
TCGA BCL2L15 440603 RNAseq -2.4649 0.0000

Upregulated datasets: 0; Downregulated datasets: 9.  


 

Survival by BCL2L15 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of BCL2L15:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 BCL2L15 440603 0 9 21
GSE20123 BCL2L15 440603 0 9 21
GSE43470 BCL2L15 440603 0 8 35
GSE46452 BCL2L15 440603 2 1 56
GSE47630 BCL2L15 440603 9 5 26
GSE54993 BCL2L15 440603 0 1 69
GSE54994 BCL2L15 440603 7 3 43
GSE60625 BCL2L15 440603 0 0 11
GSE74703 BCL2L15 440603 0 7 29
GSE74704 BCL2L15 440603 0 5 15
TCGA BCL2L15 440603 11 30 55

Total number of gains: 29; Total number of losses: 78; Total Number of normals: 381.  


 

Somatic mutations of BCL2L15:

 

Generating mutation plots.

 

Highly correlated genes for BCL2L15:

 

Showing top 20/557 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BCL2L15NICN10.747145303
BCL2L15TRNP10.742818606
BCL2L15GALK10.718947403
BCL2L15BCAS10.714771606
BCL2L15CRTAC10.711031403
BCL2L15CEACAM10.707831707
BCL2L15IL260.70728403
BCL2L15CAPN140.706393606
BCL2L15VMO10.704553303
BCL2L15C3orf350.704436303
BCL2L15CEACAM50.703727707
BCL2L15TMPRSS20.701106606
BCL2L15ATP6V0A40.698798707
BCL2L15FAM3D0.695733707
BCL2L15C9orf1520.69459404
BCL2L15SPAG170.688988403
BCL2L15PRSS270.687975707
BCL2L15HUS1B0.681017303
BCL2L15CEACAM70.680916707
BCL2L15S100P0.680516505

For details and further investigation, click here