| Full name: IQ motif containing D | Alias Symbol: DRC10|CFAP84 | ||
| Type: protein-coding gene | Cytoband: 12q24.13 | ||
| Entrez ID: 115811 | HGNC ID: HGNC:25168 | Ensembl Gene: ENSG00000166578 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of IQCD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IQCD | 115811 | 1552540_s_at | -0.3571 | 0.1100 | |
| GSE26886 | IQCD | 115811 | 1552540_s_at | -0.8888 | 0.0098 | |
| GSE45670 | IQCD | 115811 | 1552540_s_at | -0.0649 | 0.6611 | |
| GSE53622 | IQCD | 115811 | 98902 | -0.0658 | 0.3057 | |
| GSE53624 | IQCD | 115811 | 98902 | 0.0297 | 0.6971 | |
| GSE63941 | IQCD | 115811 | 1552540_s_at | 0.2371 | 0.4044 | |
| GSE77861 | IQCD | 115811 | 1552540_s_at | -0.1550 | 0.4518 | |
| GSE97050 | IQCD | 115811 | A_24_P390060 | -0.0525 | 0.8288 | |
| SRP064894 | IQCD | 115811 | RNAseq | -1.1280 | 0.0003 | |
| SRP133303 | IQCD | 115811 | RNAseq | -0.7932 | 0.0190 | |
| SRP159526 | IQCD | 115811 | RNAseq | -0.8692 | 0.0390 | |
| SRP219564 | IQCD | 115811 | RNAseq | -1.0115 | 0.0057 | |
| TCGA | IQCD | 115811 | RNAseq | 0.4692 | 0.0609 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by IQCD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IQCD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IQCD | 115811 | 4 | 3 | 23 | |
| GSE20123 | IQCD | 115811 | 4 | 3 | 23 | |
| GSE43470 | IQCD | 115811 | 2 | 0 | 41 | |
| GSE46452 | IQCD | 115811 | 9 | 1 | 49 | |
| GSE47630 | IQCD | 115811 | 9 | 3 | 28 | |
| GSE54993 | IQCD | 115811 | 0 | 5 | 65 | |
| GSE54994 | IQCD | 115811 | 4 | 2 | 47 | |
| GSE60625 | IQCD | 115811 | 0 | 0 | 11 | |
| GSE74703 | IQCD | 115811 | 2 | 0 | 34 | |
| GSE74704 | IQCD | 115811 | 2 | 2 | 16 | |
| TCGA | IQCD | 115811 | 22 | 11 | 63 |
Total number of gains: 58; Total number of losses: 30; Total Number of normals: 400.
Somatic mutations of IQCD:
Generating mutation plots.
Highly correlated genes for IQCD:
Showing top 20/261 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IQCD | ABCC8 | 0.783982 | 3 | 0 | 3 |
| IQCD | ACTL6B | 0.764734 | 3 | 0 | 3 |
| IQCD | D2HGDH | 0.760908 | 3 | 0 | 3 |
| IQCD | TMIGD2 | 0.744433 | 3 | 0 | 3 |
| IQCD | POU4F3 | 0.738082 | 3 | 0 | 3 |
| IQCD | FBF1 | 0.72714 | 3 | 0 | 3 |
| IQCD | LRRC29 | 0.726147 | 3 | 0 | 3 |
| IQCD | MYO1A | 0.722811 | 3 | 0 | 3 |
| IQCD | CHRNA10 | 0.722737 | 3 | 0 | 3 |
| IQCD | C3orf35 | 0.722087 | 3 | 0 | 3 |
| IQCD | PCDH1 | 0.717667 | 6 | 0 | 5 |
| IQCD | WDR44 | 0.715866 | 3 | 0 | 3 |
| IQCD | CNGB1 | 0.714128 | 4 | 0 | 4 |
| IQCD | NLRP6 | 0.701886 | 3 | 0 | 3 |
| IQCD | DGAT2 | 0.700842 | 3 | 0 | 3 |
| IQCD | PHLDB3 | 0.694568 | 3 | 0 | 3 |
| IQCD | TMEM184A | 0.693223 | 5 | 0 | 4 |
| IQCD | OR56A4 | 0.688397 | 3 | 0 | 3 |
| IQCD | TREML2 | 0.688053 | 3 | 0 | 3 |
| IQCD | TULP1 | 0.685639 | 3 | 0 | 3 |
For details and further investigation, click here
