| Full name: CMT1A duplicated region transcript 1 | Alias Symbol: HREP|SM25H2|FBXW10B | ||
| Type: protein-coding gene | Cytoband: 17p12 | ||
| Entrez ID: 374286 | HGNC ID: HGNC:14379 | Ensembl Gene: ENSG00000241322 | OMIM ID: 604596 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CDRT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDRT1 | 374286 | 208279_s_at | -0.2359 | 0.5092 | |
| GSE20347 | CDRT1 | 374286 | 215999_at | -0.0314 | 0.5716 | |
| GSE26886 | CDRT1 | 374286 | 215999_at | -0.2844 | 0.0054 | |
| GSE29001 | CDRT1 | 374286 | 215999_at | -0.3465 | 0.0348 | |
| GSE38129 | CDRT1 | 374286 | 208279_s_at | -0.1556 | 0.0241 | |
| GSE45670 | CDRT1 | 374286 | 215999_at | 0.1200 | 0.3340 | |
| GSE53622 | CDRT1 | 374286 | 726 | -0.3741 | 0.0582 | |
| GSE53624 | CDRT1 | 374286 | 726 | -0.6789 | 0.0000 | |
| GSE63941 | CDRT1 | 374286 | 208279_s_at | 0.6526 | 0.0166 | |
| GSE77861 | CDRT1 | 374286 | 208279_s_at | -0.1993 | 0.1239 | |
| GSE97050 | CDRT1 | 374286 | A_23_P352426 | -0.3195 | 0.2574 | |
| SRP007169 | CDRT1 | 374286 | RNAseq | -2.5937 | 0.0000 | |
| SRP064894 | CDRT1 | 374286 | RNAseq | -1.7157 | 0.0002 | |
| SRP133303 | CDRT1 | 374286 | RNAseq | -1.0131 | 0.0060 | |
| SRP159526 | CDRT1 | 374286 | RNAseq | -1.9451 | 0.0002 | |
| SRP193095 | CDRT1 | 374286 | RNAseq | -0.8907 | 0.0001 | |
| SRP219564 | CDRT1 | 374286 | RNAseq | -2.9498 | 0.0005 | |
| TCGA | CDRT1 | 374286 | RNAseq | 0.4136 | 0.2005 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by CDRT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDRT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDRT1 | 374286 | 3 | 4 | 23 | |
| GSE20123 | CDRT1 | 374286 | 3 | 5 | 22 | |
| GSE43470 | CDRT1 | 374286 | 2 | 4 | 37 | |
| GSE46452 | CDRT1 | 374286 | 34 | 1 | 24 | |
| GSE47630 | CDRT1 | 374286 | 7 | 1 | 32 | |
| GSE54993 | CDRT1 | 374286 | 3 | 3 | 64 | |
| GSE54994 | CDRT1 | 374286 | 6 | 5 | 42 | |
| GSE60625 | CDRT1 | 374286 | 4 | 0 | 7 | |
| GSE74703 | CDRT1 | 374286 | 2 | 2 | 32 | |
| GSE74704 | CDRT1 | 374286 | 2 | 2 | 16 | |
| TCGA | CDRT1 | 374286 | 18 | 22 | 56 |
Total number of gains: 84; Total number of losses: 49; Total Number of normals: 355.
Somatic mutations of CDRT1:
Generating mutation plots.
Highly correlated genes for CDRT1:
Showing top 20/533 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDRT1 | CELA3B | 0.710618 | 3 | 0 | 3 |
| CDRT1 | OTOR | 0.704478 | 3 | 0 | 3 |
| CDRT1 | OR2F2 | 0.690269 | 3 | 0 | 3 |
| CDRT1 | TP73 | 0.684091 | 3 | 0 | 3 |
| CDRT1 | C3orf35 | 0.673753 | 3 | 0 | 3 |
| CDRT1 | C8orf74 | 0.665156 | 4 | 0 | 3 |
| CDRT1 | POU4F3 | 0.656525 | 4 | 0 | 4 |
| CDRT1 | ITGA10 | 0.648737 | 4 | 0 | 4 |
| CDRT1 | LINC01056 | 0.648649 | 3 | 0 | 3 |
| CDRT1 | FGF22 | 0.648267 | 3 | 0 | 3 |
| CDRT1 | FAXDC2 | 0.646165 | 4 | 0 | 4 |
| CDRT1 | OR2H2 | 0.645464 | 4 | 0 | 4 |
| CDRT1 | OTOP3 | 0.640724 | 3 | 0 | 3 |
| CDRT1 | SLC22A18 | 0.640066 | 3 | 0 | 3 |
| CDRT1 | DNAH3 | 0.634978 | 3 | 0 | 3 |
| CDRT1 | NOX5 | 0.63101 | 6 | 0 | 4 |
| CDRT1 | LALBA | 0.629258 | 5 | 0 | 4 |
| CDRT1 | KRT76 | 0.625993 | 4 | 0 | 4 |
| CDRT1 | S100A9 | 0.625759 | 6 | 0 | 5 |
| CDRT1 | TRPM3 | 0.625448 | 3 | 0 | 3 |
For details and further investigation, click here
