| Full name: chromosome 8 open reading frame 34 | Alias Symbol: vest-1|VEST1 | ||
| Type: protein-coding gene | Cytoband: 8q13.2 | ||
| Entrez ID: 116328 | HGNC ID: HGNC:30905 | Ensembl Gene: ENSG00000165084 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C8orf34:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C8orf34 | 116328 | 231380_at | -0.1312 | 0.6391 | |
| GSE26886 | C8orf34 | 116328 | 231380_at | 0.1922 | 0.1467 | |
| GSE45670 | C8orf34 | 116328 | 231380_at | -0.3027 | 0.1301 | |
| GSE53622 | C8orf34 | 116328 | 42926 | -0.5982 | 0.0000 | |
| GSE53624 | C8orf34 | 116328 | 42926 | -0.3910 | 0.0009 | |
| GSE63941 | C8orf34 | 116328 | 231380_at | -2.4739 | 0.0000 | |
| GSE77861 | C8orf34 | 116328 | 231380_at | -0.0661 | 0.4495 | |
| SRP064894 | C8orf34 | 116328 | RNAseq | -0.7065 | 0.0372 | |
| SRP133303 | C8orf34 | 116328 | RNAseq | -0.7943 | 0.0000 | |
| SRP159526 | C8orf34 | 116328 | RNAseq | -1.2552 | 0.0111 | |
| SRP193095 | C8orf34 | 116328 | RNAseq | -0.3157 | 0.1949 | |
| SRP219564 | C8orf34 | 116328 | RNAseq | -0.9282 | 0.0675 | |
| TCGA | C8orf34 | 116328 | RNAseq | -1.6233 | 0.0008 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by C8orf34 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C8orf34:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C8orf34 | 116328 | 15 | 1 | 14 | |
| GSE20123 | C8orf34 | 116328 | 16 | 1 | 13 | |
| GSE43470 | C8orf34 | 116328 | 16 | 3 | 24 | |
| GSE46452 | C8orf34 | 116328 | 20 | 2 | 37 | |
| GSE47630 | C8orf34 | 116328 | 23 | 1 | 16 | |
| GSE54993 | C8orf34 | 116328 | 0 | 19 | 51 | |
| GSE54994 | C8orf34 | 116328 | 30 | 0 | 23 | |
| GSE60625 | C8orf34 | 116328 | 0 | 4 | 7 | |
| GSE74703 | C8orf34 | 116328 | 14 | 2 | 20 | |
| GSE74704 | C8orf34 | 116328 | 11 | 0 | 9 | |
| TCGA | C8orf34 | 116328 | 50 | 4 | 42 |
Total number of gains: 195; Total number of losses: 37; Total Number of normals: 256.
Somatic mutations of C8orf34:
Generating mutation plots.
Highly correlated genes for C8orf34:
Showing top 20/161 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C8orf34 | TCEAL7 | 0.746245 | 4 | 0 | 4 |
| C8orf34 | TCF21 | 0.704811 | 4 | 0 | 4 |
| C8orf34 | USP9Y | 0.698083 | 3 | 0 | 3 |
| C8orf34 | HEPH | 0.698075 | 4 | 0 | 3 |
| C8orf34 | ZNF382 | 0.695423 | 3 | 0 | 3 |
| C8orf34 | DDX3Y | 0.687099 | 3 | 0 | 3 |
| C8orf34 | ANO3 | 0.683478 | 3 | 0 | 3 |
| C8orf34 | GREM2 | 0.682985 | 3 | 0 | 3 |
| C8orf34 | GPC6 | 0.681127 | 4 | 0 | 3 |
| C8orf34 | FAM13C | 0.678451 | 3 | 0 | 3 |
| C8orf34 | ZNF407 | 0.671855 | 3 | 0 | 3 |
| C8orf34 | LAMA2 | 0.670316 | 5 | 0 | 4 |
| C8orf34 | TGM2 | 0.665505 | 3 | 0 | 3 |
| C8orf34 | KERA | 0.664837 | 3 | 0 | 3 |
| C8orf34 | SYT11 | 0.662364 | 4 | 0 | 3 |
| C8orf34 | LEFTY1 | 0.660018 | 3 | 0 | 3 |
| C8orf34 | CYTL1 | 0.65843 | 3 | 0 | 3 |
| C8orf34 | TMEM100 | 0.657662 | 4 | 0 | 4 |
| C8orf34 | SCG3 | 0.653724 | 3 | 0 | 3 |
| C8orf34 | TFPI2 | 0.651412 | 3 | 0 | 3 |
For details and further investigation, click here
