| Full name: keratocan | Alias Symbol: SLRR2B | ||
| Type: protein-coding gene | Cytoband: 12q21.33 | ||
| Entrez ID: 11081 | HGNC ID: HGNC:6309 | Ensembl Gene: ENSG00000139330 | OMIM ID: 603288 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of KERA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KERA | 11081 | 220504_at | -0.0552 | 0.8107 | |
| GSE20347 | KERA | 11081 | 220504_at | 0.0657 | 0.2077 | |
| GSE23400 | KERA | 11081 | 220504_at | 0.0110 | 0.5600 | |
| GSE26886 | KERA | 11081 | 220504_at | -0.0494 | 0.6044 | |
| GSE29001 | KERA | 11081 | 220504_at | 0.0324 | 0.8168 | |
| GSE38129 | KERA | 11081 | 220504_at | 0.0451 | 0.5551 | |
| GSE45670 | KERA | 11081 | 220504_at | 0.0978 | 0.1801 | |
| GSE53622 | KERA | 11081 | 48692 | 0.9256 | 0.0000 | |
| GSE53624 | KERA | 11081 | 48692 | 1.1800 | 0.0000 | |
| GSE63941 | KERA | 11081 | 220504_at | -0.3031 | 0.0091 | |
| GSE77861 | KERA | 11081 | 220504_at | -0.0331 | 0.7034 | |
| TCGA | KERA | 11081 | RNAseq | -0.3092 | 0.6510 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KERA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KERA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KERA | 11081 | 3 | 2 | 25 | |
| GSE20123 | KERA | 11081 | 3 | 2 | 25 | |
| GSE43470 | KERA | 11081 | 3 | 0 | 40 | |
| GSE46452 | KERA | 11081 | 9 | 1 | 49 | |
| GSE47630 | KERA | 11081 | 10 | 1 | 29 | |
| GSE54993 | KERA | 11081 | 0 | 6 | 64 | |
| GSE54994 | KERA | 11081 | 6 | 1 | 46 | |
| GSE60625 | KERA | 11081 | 0 | 0 | 11 | |
| GSE74703 | KERA | 11081 | 3 | 0 | 33 | |
| GSE74704 | KERA | 11081 | 1 | 2 | 17 | |
| TCGA | KERA | 11081 | 17 | 12 | 67 |
Total number of gains: 55; Total number of losses: 27; Total Number of normals: 406.
Somatic mutations of KERA:
Generating mutation plots.
Highly correlated genes for KERA:
Showing top 20/187 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KERA | CLIP3 | 0.709385 | 4 | 0 | 4 |
| KERA | ZNF471 | 0.709151 | 3 | 0 | 3 |
| KERA | CACNA1H | 0.704502 | 3 | 0 | 3 |
| KERA | BHMT2 | 0.689408 | 3 | 0 | 3 |
| KERA | CPED1 | 0.685696 | 3 | 0 | 3 |
| KERA | PCDH9 | 0.677905 | 3 | 0 | 3 |
| KERA | C3orf18 | 0.675117 | 3 | 0 | 3 |
| KERA | PIP5K1C | 0.667095 | 3 | 0 | 3 |
| KERA | DENND2A | 0.666807 | 3 | 0 | 3 |
| KERA | KITLG | 0.66657 | 3 | 0 | 3 |
| KERA | RAB23 | 0.66484 | 4 | 0 | 4 |
| KERA | C8orf34 | 0.664837 | 3 | 0 | 3 |
| KERA | EPHA7 | 0.658896 | 4 | 0 | 3 |
| KERA | GDNF | 0.656355 | 4 | 0 | 3 |
| KERA | KANK2 | 0.651315 | 3 | 0 | 3 |
| KERA | OR1F1 | 0.646952 | 4 | 0 | 3 |
| KERA | CYP7A1 | 0.645615 | 3 | 0 | 3 |
| KERA | CASQ1 | 0.64421 | 4 | 0 | 3 |
| KERA | GFRA1 | 0.644051 | 4 | 0 | 3 |
| KERA | STARD13 | 0.637381 | 3 | 0 | 3 |
For details and further investigation, click here
