| Full name: secretogranin III | Alias Symbol: SgIII|FLJ90833 | ||
| Type: protein-coding gene | Cytoband: 15q21.2 | ||
| Entrez ID: 29106 | HGNC ID: HGNC:13707 | Ensembl Gene: ENSG00000104112 | OMIM ID: 611796 |
| Drug and gene relationship at DGIdb | |||
Expression of SCG3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCG3 | 29106 | 219196_at | -0.1769 | 0.3040 | |
| GSE20347 | SCG3 | 29106 | 219196_at | -0.0825 | 0.0534 | |
| GSE23400 | SCG3 | 29106 | 219196_at | -0.0513 | 0.0007 | |
| GSE26886 | SCG3 | 29106 | 219196_at | 0.0315 | 0.7272 | |
| GSE29001 | SCG3 | 29106 | 219196_at | -0.0625 | 0.5024 | |
| GSE38129 | SCG3 | 29106 | 219196_at | -0.0733 | 0.7448 | |
| GSE45670 | SCG3 | 29106 | 219196_at | 0.1117 | 0.7804 | |
| GSE53622 | SCG3 | 29106 | 34309 | -0.6491 | 0.0028 | |
| GSE53624 | SCG3 | 29106 | 34309 | -0.5606 | 0.0006 | |
| GSE63941 | SCG3 | 29106 | 219196_at | 0.0502 | 0.6998 | |
| GSE77861 | SCG3 | 29106 | 219196_at | -0.0487 | 0.5072 | |
| SRP064894 | SCG3 | 29106 | RNAseq | -0.3012 | 0.2395 | |
| SRP133303 | SCG3 | 29106 | RNAseq | -0.3567 | 0.0027 | |
| SRP159526 | SCG3 | 29106 | RNAseq | 0.0244 | 0.9530 | |
| SRP193095 | SCG3 | 29106 | RNAseq | -0.0609 | 0.7174 | |
| SRP219564 | SCG3 | 29106 | RNAseq | -0.3887 | 0.3912 | |
| TCGA | SCG3 | 29106 | RNAseq | -3.7563 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SCG3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCG3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCG3 | 29106 | 6 | 4 | 20 | |
| GSE20123 | SCG3 | 29106 | 6 | 4 | 20 | |
| GSE43470 | SCG3 | 29106 | 4 | 3 | 36 | |
| GSE46452 | SCG3 | 29106 | 3 | 7 | 49 | |
| GSE47630 | SCG3 | 29106 | 8 | 10 | 22 | |
| GSE54993 | SCG3 | 29106 | 4 | 6 | 60 | |
| GSE54994 | SCG3 | 29106 | 5 | 7 | 41 | |
| GSE60625 | SCG3 | 29106 | 4 | 0 | 7 | |
| GSE74703 | SCG3 | 29106 | 4 | 2 | 30 | |
| GSE74704 | SCG3 | 29106 | 2 | 3 | 15 | |
| TCGA | SCG3 | 29106 | 9 | 17 | 70 |
Total number of gains: 55; Total number of losses: 63; Total Number of normals: 370.
Somatic mutations of SCG3:
Generating mutation plots.
Highly correlated genes for SCG3:
Showing top 20/241 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCG3 | RAVER2 | 0.708614 | 4 | 0 | 4 |
| SCG3 | HRC | 0.695988 | 3 | 0 | 3 |
| SCG3 | GRIA1 | 0.691805 | 4 | 0 | 3 |
| SCG3 | SLC6A5 | 0.690059 | 3 | 0 | 3 |
| SCG3 | LEFTY1 | 0.69002 | 3 | 0 | 3 |
| SCG3 | BPY2 | 0.686896 | 3 | 0 | 3 |
| SCG3 | TAS2R16 | 0.682176 | 3 | 0 | 3 |
| SCG3 | PHOX2B | 0.676736 | 3 | 0 | 3 |
| SCG3 | CYP2A7 | 0.66717 | 3 | 0 | 3 |
| SCG3 | KHDRBS2 | 0.665909 | 3 | 0 | 3 |
| SCG3 | PSG6 | 0.663332 | 3 | 0 | 3 |
| SCG3 | ZMAT4 | 0.66177 | 4 | 0 | 3 |
| SCG3 | PDE1C | 0.660895 | 4 | 0 | 4 |
| SCG3 | USH1C | 0.655082 | 3 | 0 | 3 |
| SCG3 | C8orf34 | 0.653724 | 3 | 0 | 3 |
| SCG3 | SI | 0.652544 | 3 | 0 | 3 |
| SCG3 | MTAP | 0.649294 | 3 | 0 | 3 |
| SCG3 | MSH4 | 0.648907 | 5 | 0 | 4 |
| SCG3 | CBLN1 | 0.644871 | 4 | 0 | 3 |
| SCG3 | PSG7 | 0.643314 | 3 | 0 | 3 |
For details and further investigation, click here
