| Full name: cytokine like 1 | Alias Symbol: C17|C4orf4 | ||
| Type: protein-coding gene | Cytoband: 4p16.2 | ||
| Entrez ID: 54360 | HGNC ID: HGNC:24435 | Ensembl Gene: ENSG00000170891 | OMIM ID: 607930 |
| Drug and gene relationship at DGIdb | |||
Expression of CYTL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYTL1 | 54360 | 219837_s_at | -0.7287 | 0.4351 | |
| GSE20347 | CYTL1 | 54360 | 219837_s_at | -0.1601 | 0.0444 | |
| GSE23400 | CYTL1 | 54360 | 219837_s_at | -0.1698 | 0.0000 | |
| GSE26886 | CYTL1 | 54360 | 219837_s_at | -0.0949 | 0.4934 | |
| GSE29001 | CYTL1 | 54360 | 219837_s_at | -0.1118 | 0.4811 | |
| GSE38129 | CYTL1 | 54360 | 219837_s_at | -0.2695 | 0.3015 | |
| GSE45670 | CYTL1 | 54360 | 219837_s_at | -1.1102 | 0.0030 | |
| GSE53622 | CYTL1 | 54360 | 69072 | -0.1437 | 0.2232 | |
| GSE53624 | CYTL1 | 54360 | 69072 | -0.4992 | 0.0004 | |
| GSE63941 | CYTL1 | 54360 | 219837_s_at | -4.5071 | 0.0000 | |
| GSE77861 | CYTL1 | 54360 | 219837_s_at | -0.0752 | 0.4403 | |
| GSE97050 | CYTL1 | 54360 | A_33_P3252695 | 0.3186 | 0.3296 | |
| SRP064894 | CYTL1 | 54360 | RNAseq | -0.1042 | 0.7839 | |
| SRP133303 | CYTL1 | 54360 | RNAseq | -1.4125 | 0.0001 | |
| SRP159526 | CYTL1 | 54360 | RNAseq | -0.6938 | 0.2349 | |
| SRP219564 | CYTL1 | 54360 | RNAseq | -0.3714 | 0.5507 | |
| TCGA | CYTL1 | 54360 | RNAseq | -0.5852 | 0.0752 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by CYTL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CYTL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYTL1 | 54360 | 0 | 16 | 14 | |
| GSE20123 | CYTL1 | 54360 | 0 | 16 | 14 | |
| GSE43470 | CYTL1 | 54360 | 0 | 16 | 27 | |
| GSE46452 | CYTL1 | 54360 | 1 | 36 | 22 | |
| GSE47630 | CYTL1 | 54360 | 1 | 19 | 20 | |
| GSE54993 | CYTL1 | 54360 | 10 | 0 | 60 | |
| GSE54994 | CYTL1 | 54360 | 3 | 12 | 38 | |
| GSE60625 | CYTL1 | 54360 | 0 | 0 | 11 | |
| GSE74703 | CYTL1 | 54360 | 0 | 13 | 23 | |
| GSE74704 | CYTL1 | 54360 | 0 | 9 | 11 | |
| TCGA | CYTL1 | 54360 | 7 | 47 | 42 |
Total number of gains: 22; Total number of losses: 184; Total Number of normals: 282.
Somatic mutations of CYTL1:
Generating mutation plots.
Highly correlated genes for CYTL1:
Showing top 20/154 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYTL1 | CCL11 | 0.729245 | 4 | 0 | 4 |
| CYTL1 | ZNF521 | 0.709884 | 5 | 0 | 4 |
| CYTL1 | LSAMP | 0.706578 | 3 | 0 | 3 |
| CYTL1 | SPON1 | 0.701097 | 5 | 0 | 4 |
| CYTL1 | LINC00968 | 0.689502 | 3 | 0 | 3 |
| CYTL1 | LAMA2 | 0.686634 | 5 | 0 | 4 |
| CYTL1 | PABPC5 | 0.683483 | 3 | 0 | 3 |
| CYTL1 | SLITRK4 | 0.682299 | 3 | 0 | 3 |
| CYTL1 | SMIM10 | 0.670365 | 3 | 0 | 3 |
| CYTL1 | LXN | 0.662047 | 4 | 0 | 3 |
| CYTL1 | C8orf34 | 0.65843 | 3 | 0 | 3 |
| CYTL1 | CNTN4 | 0.654459 | 5 | 0 | 3 |
| CYTL1 | ENTPD1 | 0.648861 | 5 | 0 | 3 |
| CYTL1 | TBX5-AS1 | 0.645228 | 3 | 0 | 3 |
| CYTL1 | PLXDC2 | 0.640799 | 4 | 0 | 3 |
| CYTL1 | HDX | 0.639175 | 3 | 0 | 3 |
| CYTL1 | FAM155A | 0.638851 | 6 | 0 | 5 |
| CYTL1 | CHGA | 0.625962 | 3 | 0 | 3 |
| CYTL1 | ZFPM2 | 0.625584 | 4 | 0 | 4 |
| CYTL1 | ROBO2 | 0.619817 | 4 | 0 | 3 |
For details and further investigation, click here
