| Full name: teashirt zinc finger homeobox 3 | Alias Symbol: KIAA1474|TSH3 | ||
| Type: protein-coding gene | Cytoband: 19q12 | ||
| Entrez ID: 57616 | HGNC ID: HGNC:30700 | Ensembl Gene: ENSG00000121297 | OMIM ID: 614119 |
| Drug and gene relationship at DGIdb | |||
Expression of TSHZ3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TSHZ3 | 57616 | 223392_s_at | -0.4699 | 0.4975 | |
| GSE26886 | TSHZ3 | 57616 | 223392_s_at | 0.6278 | 0.0013 | |
| GSE45670 | TSHZ3 | 57616 | 223392_s_at | -0.2790 | 0.4421 | |
| GSE53622 | TSHZ3 | 57616 | 758 | 0.2173 | 0.1843 | |
| GSE53624 | TSHZ3 | 57616 | 758 | 0.4154 | 0.0021 | |
| GSE63941 | TSHZ3 | 57616 | 223393_s_at | -3.0106 | 0.0056 | |
| GSE77861 | TSHZ3 | 57616 | 223392_s_at | -0.0125 | 0.9544 | |
| GSE97050 | TSHZ3 | 57616 | A_23_P361014 | -0.1423 | 0.6428 | |
| SRP007169 | TSHZ3 | 57616 | RNAseq | 2.0227 | 0.0007 | |
| SRP008496 | TSHZ3 | 57616 | RNAseq | 2.6995 | 0.0000 | |
| SRP064894 | TSHZ3 | 57616 | RNAseq | 0.6375 | 0.0137 | |
| SRP133303 | TSHZ3 | 57616 | RNAseq | 0.7271 | 0.0129 | |
| SRP159526 | TSHZ3 | 57616 | RNAseq | -0.0565 | 0.8791 | |
| SRP193095 | TSHZ3 | 57616 | RNAseq | 1.5311 | 0.0000 | |
| SRP219564 | TSHZ3 | 57616 | RNAseq | 0.0135 | 0.9813 | |
| TCGA | TSHZ3 | 57616 | RNAseq | -0.0214 | 0.8706 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by TSHZ3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TSHZ3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TSHZ3 | 57616 | 8 | 8 | 14 | |
| GSE20123 | TSHZ3 | 57616 | 7 | 7 | 16 | |
| GSE43470 | TSHZ3 | 57616 | 6 | 6 | 31 | |
| GSE46452 | TSHZ3 | 57616 | 47 | 1 | 11 | |
| GSE47630 | TSHZ3 | 57616 | 8 | 6 | 26 | |
| GSE54993 | TSHZ3 | 57616 | 17 | 3 | 50 | |
| GSE54994 | TSHZ3 | 57616 | 7 | 11 | 35 | |
| GSE60625 | TSHZ3 | 57616 | 9 | 0 | 2 | |
| GSE74703 | TSHZ3 | 57616 | 6 | 4 | 26 | |
| GSE74704 | TSHZ3 | 57616 | 6 | 5 | 9 | |
| TCGA | TSHZ3 | 57616 | 19 | 12 | 65 |
Total number of gains: 140; Total number of losses: 63; Total Number of normals: 285.
Somatic mutations of TSHZ3:
Generating mutation plots.
Highly correlated genes for TSHZ3:
Showing top 20/847 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TSHZ3 | FRY | 0.804053 | 3 | 0 | 3 |
| TSHZ3 | NFIC | 0.783112 | 3 | 0 | 3 |
| TSHZ3 | ANK2 | 0.771917 | 3 | 0 | 3 |
| TSHZ3 | SLC2A13 | 0.769321 | 3 | 0 | 3 |
| TSHZ3 | PEG3 | 0.766787 | 3 | 0 | 3 |
| TSHZ3 | NME5 | 0.765542 | 3 | 0 | 3 |
| TSHZ3 | ASPA | 0.760798 | 3 | 0 | 3 |
| TSHZ3 | DZIP1L | 0.749621 | 3 | 0 | 3 |
| TSHZ3 | IL33 | 0.746082 | 3 | 0 | 3 |
| TSHZ3 | ANO5 | 0.744698 | 3 | 0 | 3 |
| TSHZ3 | GFRA1 | 0.743555 | 3 | 0 | 3 |
| TSHZ3 | CABIN1 | 0.743291 | 3 | 0 | 3 |
| TSHZ3 | ZEB1 | 0.739024 | 3 | 0 | 3 |
| TSHZ3 | MRC2 | 0.738746 | 3 | 0 | 3 |
| TSHZ3 | GPRASP1 | 0.738245 | 3 | 0 | 3 |
| TSHZ3 | NFASC | 0.732258 | 3 | 0 | 3 |
| TSHZ3 | C20orf194 | 0.72988 | 3 | 0 | 3 |
| TSHZ3 | SLC4A4 | 0.728796 | 3 | 0 | 3 |
| TSHZ3 | PI16 | 0.725239 | 3 | 0 | 3 |
| TSHZ3 | IGFBP5 | 0.72513 | 3 | 0 | 3 |
For details and further investigation, click here
