| Full name: RAB1B, member RAS oncogene family | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 81876 | HGNC ID: HGNC:18370 | Ensembl Gene: ENSG00000174903 | OMIM ID: 612565 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RAB1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RAB1B | 81876 | 220964_s_at | 0.2267 | 0.5436 | |
| GSE20347 | RAB1B | 81876 | 220964_s_at | -0.3171 | 0.0259 | |
| GSE23400 | RAB1B | 81876 | 220964_s_at | -0.1515 | 0.0021 | |
| GSE26886 | RAB1B | 81876 | 220964_s_at | -0.0879 | 0.6983 | |
| GSE29001 | RAB1B | 81876 | 220964_s_at | -0.2919 | 0.4107 | |
| GSE38129 | RAB1B | 81876 | 220964_s_at | -0.3006 | 0.0036 | |
| GSE45670 | RAB1B | 81876 | 220964_s_at | -0.0495 | 0.7132 | |
| GSE53622 | RAB1B | 81876 | 26731 | -0.1799 | 0.0176 | |
| GSE53624 | RAB1B | 81876 | 26731 | -0.2161 | 0.0004 | |
| GSE63941 | RAB1B | 81876 | 220964_s_at | 0.7296 | 0.0886 | |
| GSE77861 | RAB1B | 81876 | 220964_s_at | 0.0184 | 0.9532 | |
| GSE97050 | RAB1B | 81876 | A_33_P3329607 | -0.1733 | 0.4011 | |
| SRP007169 | RAB1B | 81876 | RNAseq | -1.6451 | 0.0000 | |
| SRP008496 | RAB1B | 81876 | RNAseq | -1.4959 | 0.0000 | |
| SRP064894 | RAB1B | 81876 | RNAseq | -0.3212 | 0.1627 | |
| SRP133303 | RAB1B | 81876 | RNAseq | -0.1516 | 0.5075 | |
| SRP159526 | RAB1B | 81876 | RNAseq | -0.4795 | 0.0072 | |
| SRP193095 | RAB1B | 81876 | RNAseq | -0.4058 | 0.0027 | |
| SRP219564 | RAB1B | 81876 | RNAseq | -0.3345 | 0.3329 | |
| TCGA | RAB1B | 81876 | RNAseq | 0.0007 | 0.9872 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by RAB1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RAB1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RAB1B | 81876 | 9 | 4 | 17 | |
| GSE20123 | RAB1B | 81876 | 9 | 4 | 17 | |
| GSE43470 | RAB1B | 81876 | 6 | 1 | 36 | |
| GSE46452 | RAB1B | 81876 | 11 | 3 | 45 | |
| GSE47630 | RAB1B | 81876 | 8 | 5 | 27 | |
| GSE54993 | RAB1B | 81876 | 3 | 0 | 67 | |
| GSE54994 | RAB1B | 81876 | 8 | 5 | 40 | |
| GSE60625 | RAB1B | 81876 | 0 | 3 | 8 | |
| GSE74703 | RAB1B | 81876 | 4 | 0 | 32 | |
| GSE74704 | RAB1B | 81876 | 7 | 2 | 11 | |
| TCGA | RAB1B | 81876 | 25 | 6 | 65 |
Total number of gains: 90; Total number of losses: 33; Total Number of normals: 365.
Somatic mutations of RAB1B:
Generating mutation plots.
Highly correlated genes for RAB1B:
Showing top 20/370 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RAB1B | RAB7A | 0.825446 | 3 | 0 | 3 |
| RAB1B | MRPL11 | 0.817572 | 3 | 0 | 3 |
| RAB1B | SORBS3 | 0.814217 | 3 | 0 | 3 |
| RAB1B | PIP4K2C | 0.809902 | 3 | 0 | 3 |
| RAB1B | RAD18 | 0.77729 | 3 | 0 | 3 |
| RAB1B | FAM193A | 0.762146 | 3 | 0 | 3 |
| RAB1B | PRR12 | 0.761577 | 3 | 0 | 3 |
| RAB1B | ERP27 | 0.761378 | 3 | 0 | 3 |
| RAB1B | PROSER1 | 0.756058 | 3 | 0 | 3 |
| RAB1B | HTT | 0.742539 | 3 | 0 | 3 |
| RAB1B | CABIN1 | 0.740787 | 3 | 0 | 3 |
| RAB1B | FPGS | 0.737975 | 3 | 0 | 3 |
| RAB1B | PTBP1 | 0.736947 | 3 | 0 | 3 |
| RAB1B | U2AF2 | 0.730215 | 3 | 0 | 3 |
| RAB1B | SPNS1 | 0.727039 | 3 | 0 | 3 |
| RAB1B | SLC35C2 | 0.723902 | 4 | 0 | 4 |
| RAB1B | BCORL1 | 0.719448 | 3 | 0 | 3 |
| RAB1B | LAMP1 | 0.717959 | 3 | 0 | 3 |
| RAB1B | TMCO6 | 0.717136 | 3 | 0 | 3 |
| RAB1B | HGS | 0.715796 | 5 | 0 | 5 |
For details and further investigation, click here
