BATF2

 

Full name: basic leucine zipper ATF-like transcription factor 2 Alias Symbol: MGC20410
Type: protein-coding gene Cytoband: 11q13.1
Entrez ID: 116071 HGNC ID: HGNC:25163 Ensembl Gene: ENSG00000168062 OMIM ID: 614983
Drug and gene relationship at DGIdb

 

Expression of BATF2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 BATF2 116071 228439_at 0.4023 0.5665
GSE26886 BATF2 116071 228439_at 0.4461 0.0760
GSE45670 BATF2 116071 228439_at 0.6126 0.0658
GSE53622 BATF2 116071 35558 0.8236 0.0000
GSE53624 BATF2 116071 35558 1.0893 0.0000
GSE63941 BATF2 116071 228439_at -0.1603 0.5405
GSE77861 BATF2 116071 228439_at 0.0242 0.8054
GSE97050 BATF2 116071 A_23_P370682 0.7822 0.2141
SRP007169 BATF2 116071 RNAseq 4.4841 0.0010
SRP064894 BATF2 116071 RNAseq 1.3632 0.0023
SRP133303 BATF2 116071 RNAseq 1.9035 0.0000
SRP159526 BATF2 116071 RNAseq 0.4146 0.5567
SRP219564 BATF2 116071 RNAseq 2.5526 0.0100
TCGA BATF2 116071 RNAseq 0.1051 0.6910

Upregulated datasets: 5; Downregulated datasets: 0.  


 

Survival by BATF2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of BATF2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 BATF2 116071 7 6 17
GSE20123 BATF2 116071 7 6 17
GSE43470 BATF2 116071 1 3 39
GSE46452 BATF2 116071 10 4 45
GSE47630 BATF2 116071 5 6 29
GSE54993 BATF2 116071 3 0 67
GSE54994 BATF2 116071 6 5 42
GSE60625 BATF2 116071 0 3 8
GSE74703 BATF2 116071 1 1 34
GSE74704 BATF2 116071 5 4 11
TCGA BATF2 116071 23 7 66

Total number of gains: 68; Total number of losses: 45; Total Number of normals: 375.  


 

Somatic mutations of BATF2:

 

Generating mutation plots.

 

Highly correlated genes for BATF2:

 

Showing top 20/146 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
BATF2PSTPIP10.771382303
BATF2LRFN10.732063303
BATF2FCGR1B0.726787505
BATF2TBX210.711342303
BATF2PARP100.706657505
BATF2AKNA0.701066303
BATF2OGFR0.69694303
BATF2CHIT10.69634404
BATF2PHKA20.692774303
BATF2DOHH0.692768303
BATF2GNLY0.691211705
BATF2CXCL100.688051706
BATF2PSMB90.686629605
BATF2GCNT70.685823303
BATF2CXCL110.684494706
BATF2HTRA40.681834403
BATF2CADM40.679245303
BATF2SDSL0.678111504
BATF2TOE10.676044303
BATF2HLA-F0.66507504

For details and further investigation, click here