| Full name: von Willebrand factor D and EGF domains | Alias Symbol: FLJ14712 | ||
| Type: protein-coding gene | Cytoband: 7p21.3 | ||
| Entrez ID: 221806 | HGNC ID: HGNC:21897 | Ensembl Gene: ENSG00000146530 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of VWDE:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VWDE | 221806 | 239552_at | -0.1000 | 0.8364 | |
| GSE26886 | VWDE | 221806 | 239552_at | 0.6877 | 0.0471 | |
| GSE45670 | VWDE | 221806 | 239552_at | -0.0161 | 0.9656 | |
| GSE53622 | VWDE | 221806 | 11128 | 0.1894 | 0.4633 | |
| GSE53624 | VWDE | 221806 | 4025 | -0.2455 | 0.2598 | |
| GSE63941 | VWDE | 221806 | 1562226_at | 2.3307 | 0.0327 | |
| GSE77861 | VWDE | 221806 | 1562226_at | 0.0295 | 0.8160 | |
| GSE97050 | VWDE | 221806 | A_23_P381505 | 0.0035 | 0.9898 | |
| SRP133303 | VWDE | 221806 | RNAseq | 0.3435 | 0.6010 | |
| SRP159526 | VWDE | 221806 | RNAseq | 1.2897 | 0.0249 | |
| TCGA | VWDE | 221806 | RNAseq | 1.6235 | 0.0164 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by VWDE expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VWDE:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VWDE | 221806 | 14 | 2 | 14 | |
| GSE20123 | VWDE | 221806 | 14 | 2 | 14 | |
| GSE43470 | VWDE | 221806 | 5 | 0 | 38 | |
| GSE46452 | VWDE | 221806 | 11 | 1 | 47 | |
| GSE47630 | VWDE | 221806 | 9 | 1 | 30 | |
| GSE54993 | VWDE | 221806 | 0 | 6 | 64 | |
| GSE54994 | VWDE | 221806 | 22 | 1 | 30 | |
| GSE60625 | VWDE | 221806 | 0 | 0 | 11 | |
| GSE74703 | VWDE | 221806 | 5 | 0 | 31 | |
| GSE74704 | VWDE | 221806 | 8 | 2 | 10 | |
| TCGA | VWDE | 221806 | 54 | 7 | 35 |
Total number of gains: 142; Total number of losses: 22; Total Number of normals: 324.
Somatic mutations of VWDE:
Generating mutation plots.
Highly correlated genes for VWDE:
Showing top 20/34 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VWDE | LYPD6 | 0.723598 | 3 | 0 | 3 |
| VWDE | PRR15 | 0.703963 | 3 | 0 | 3 |
| VWDE | CADM4 | 0.702282 | 3 | 0 | 3 |
| VWDE | MPP3 | 0.702178 | 4 | 0 | 3 |
| VWDE | BTBD9 | 0.696638 | 3 | 0 | 3 |
| VWDE | ACTR3B | 0.67147 | 3 | 0 | 3 |
| VWDE | EPB41L4B | 0.668424 | 3 | 0 | 3 |
| VWDE | SLC27A2 | 0.66346 | 3 | 0 | 3 |
| VWDE | TDRD10 | 0.660922 | 3 | 0 | 3 |
| VWDE | ZBTB48 | 0.654906 | 3 | 0 | 3 |
| VWDE | WRAP73 | 0.644547 | 3 | 0 | 3 |
| VWDE | SLC27A1 | 0.642335 | 3 | 0 | 3 |
| VWDE | KLRG2 | 0.641756 | 3 | 0 | 3 |
| VWDE | RTBDN | 0.640509 | 3 | 0 | 3 |
| VWDE | NRK | 0.629749 | 4 | 0 | 3 |
| VWDE | CCDC130 | 0.625953 | 3 | 0 | 3 |
| VWDE | GRTP1 | 0.62486 | 4 | 0 | 4 |
| VWDE | GPC3 | 0.613185 | 4 | 0 | 3 |
| VWDE | CSAD | 0.609057 | 3 | 0 | 3 |
| VWDE | ZNF232 | 0.594066 | 4 | 0 | 3 |
For details and further investigation, click here
