| Full name: zinc finger MYND-type containing 8 | Alias Symbol: RACK7 | ||
| Type: protein-coding gene | Cytoband: 20q13.12 | ||
| Entrez ID: 23613 | HGNC ID: HGNC:9397 | Ensembl Gene: ENSG00000101040 | OMIM ID: 615713 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZMYND8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZMYND8 | 23613 | 209048_s_at | 0.0245 | 0.9771 | |
| GSE20347 | ZMYND8 | 23613 | 209049_s_at | 0.4449 | 0.0067 | |
| GSE23400 | ZMYND8 | 23613 | 209048_s_at | 0.0226 | 0.8493 | |
| GSE26886 | ZMYND8 | 23613 | 209048_s_at | 0.3140 | 0.4433 | |
| GSE29001 | ZMYND8 | 23613 | 209049_s_at | 0.2748 | 0.5098 | |
| GSE38129 | ZMYND8 | 23613 | 209049_s_at | 0.3859 | 0.0173 | |
| GSE45670 | ZMYND8 | 23613 | 209049_s_at | 0.4259 | 0.0098 | |
| GSE53622 | ZMYND8 | 23613 | 107293 | 0.1997 | 0.0079 | |
| GSE53624 | ZMYND8 | 23613 | 107293 | 0.1150 | 0.0821 | |
| GSE63941 | ZMYND8 | 23613 | 209049_s_at | 0.6478 | 0.3900 | |
| GSE77861 | ZMYND8 | 23613 | 209048_s_at | 0.1255 | 0.7550 | |
| GSE97050 | ZMYND8 | 23613 | A_33_P3619221 | 0.2433 | 0.3928 | |
| SRP007169 | ZMYND8 | 23613 | RNAseq | 0.7585 | 0.1406 | |
| SRP008496 | ZMYND8 | 23613 | RNAseq | 0.2125 | 0.5407 | |
| SRP064894 | ZMYND8 | 23613 | RNAseq | 0.0406 | 0.8148 | |
| SRP133303 | ZMYND8 | 23613 | RNAseq | 0.2529 | 0.1197 | |
| SRP159526 | ZMYND8 | 23613 | RNAseq | -0.0892 | 0.7036 | |
| SRP193095 | ZMYND8 | 23613 | RNAseq | 0.0841 | 0.6147 | |
| SRP219564 | ZMYND8 | 23613 | RNAseq | -0.0551 | 0.8888 | |
| TCGA | ZMYND8 | 23613 | RNAseq | -0.1342 | 0.0040 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZMYND8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZMYND8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZMYND8 | 23613 | 15 | 2 | 13 | |
| GSE20123 | ZMYND8 | 23613 | 15 | 2 | 13 | |
| GSE43470 | ZMYND8 | 23613 | 12 | 1 | 30 | |
| GSE46452 | ZMYND8 | 23613 | 29 | 0 | 30 | |
| GSE47630 | ZMYND8 | 23613 | 24 | 1 | 15 | |
| GSE54993 | ZMYND8 | 23613 | 0 | 18 | 52 | |
| GSE54994 | ZMYND8 | 23613 | 26 | 0 | 27 | |
| GSE60625 | ZMYND8 | 23613 | 0 | 0 | 11 | |
| GSE74703 | ZMYND8 | 23613 | 10 | 1 | 25 | |
| GSE74704 | ZMYND8 | 23613 | 11 | 0 | 9 | |
| TCGA | ZMYND8 | 23613 | 45 | 3 | 48 |
Total number of gains: 187; Total number of losses: 28; Total Number of normals: 273.
Somatic mutations of ZMYND8:
Generating mutation plots.
Highly correlated genes for ZMYND8:
Showing top 20/62 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZMYND8 | GPC2 | 0.675132 | 3 | 0 | 3 |
| ZMYND8 | CADM4 | 0.665679 | 3 | 0 | 3 |
| ZMYND8 | PRR15 | 0.664872 | 3 | 0 | 3 |
| ZMYND8 | MFSD11 | 0.663794 | 4 | 0 | 3 |
| ZMYND8 | GRIPAP1 | 0.657455 | 4 | 0 | 3 |
| ZMYND8 | ADPRHL2 | 0.649769 | 3 | 0 | 3 |
| ZMYND8 | TSR1 | 0.633104 | 3 | 0 | 3 |
| ZMYND8 | CCDC122 | 0.631674 | 3 | 0 | 3 |
| ZMYND8 | TNFRSF14 | 0.616409 | 3 | 0 | 3 |
| ZMYND8 | SLC27A5 | 0.614449 | 4 | 0 | 3 |
| ZMYND8 | ORC6 | 0.611299 | 4 | 0 | 3 |
| ZMYND8 | PABPC1 | 0.597041 | 3 | 0 | 3 |
| ZMYND8 | NLRP2 | 0.59131 | 3 | 0 | 3 |
| ZMYND8 | TUG1 | 0.581795 | 5 | 0 | 4 |
| ZMYND8 | MSLN | 0.579392 | 3 | 0 | 3 |
| ZMYND8 | BMP8B | 0.578537 | 4 | 0 | 3 |
| ZMYND8 | CCNL2 | 0.576648 | 8 | 0 | 6 |
| ZMYND8 | PGF | 0.573784 | 4 | 0 | 3 |
| ZMYND8 | PRPF31 | 0.56891 | 6 | 0 | 3 |
| ZMYND8 | ATG4D | 0.568235 | 4 | 0 | 3 |
For details and further investigation, click here
