| Full name: collagen type IV alpha 5 chain | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: Xq22.3 | ||
| Entrez ID: 1287 | HGNC ID: HGNC:2207 | Ensembl Gene: ENSG00000188153 | OMIM ID: 303630 |
| Drug and gene relationship at DGIdb | |||
COL4A5 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04151 | PI3K-Akt signaling pathway | |
| hsa04510 | Focal adhesion | |
| hsa05200 | Pathways in cancer | |
| hsa05222 | Small cell lung cancer |
Expression of COL4A5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COL4A5 | 1287 | 213110_s_at | 0.4094 | 0.7602 | |
| GSE20347 | COL4A5 | 1287 | 213110_s_at | 1.6226 | 0.0000 | |
| GSE23400 | COL4A5 | 1287 | 213110_s_at | 0.7998 | 0.0006 | |
| GSE26886 | COL4A5 | 1287 | 213110_s_at | 3.6186 | 0.0000 | |
| GSE29001 | COL4A5 | 1287 | 213110_s_at | 1.0472 | 0.0026 | |
| GSE38129 | COL4A5 | 1287 | 213110_s_at | 0.8004 | 0.0446 | |
| GSE45670 | COL4A5 | 1287 | 213110_s_at | 0.2314 | 0.6848 | |
| GSE53622 | COL4A5 | 1287 | 44143 | 1.2926 | 0.0000 | |
| GSE53624 | COL4A5 | 1287 | 44143 | 1.3390 | 0.0000 | |
| GSE63941 | COL4A5 | 1287 | 213110_s_at | -0.0758 | 0.9438 | |
| GSE77861 | COL4A5 | 1287 | 213110_s_at | 2.1475 | 0.0213 | |
| GSE97050 | COL4A5 | 1287 | A_23_P45365 | -0.9939 | 0.2448 | |
| SRP007169 | COL4A5 | 1287 | RNAseq | 3.7206 | 0.0000 | |
| SRP008496 | COL4A5 | 1287 | RNAseq | 4.2397 | 0.0000 | |
| SRP064894 | COL4A5 | 1287 | RNAseq | 0.9961 | 0.0006 | |
| SRP133303 | COL4A5 | 1287 | RNAseq | 1.1765 | 0.0030 | |
| SRP193095 | COL4A5 | 1287 | RNAseq | 1.8996 | 0.0000 | |
| SRP219564 | COL4A5 | 1287 | RNAseq | 0.5540 | 0.4870 | |
| TCGA | COL4A5 | 1287 | RNAseq | -0.0117 | 0.9032 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by COL4A5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COL4A5:
No record found for this gene.
Somatic mutations of COL4A5:
Generating mutation plots.
Highly correlated genes for COL4A5:
Showing top 20/1097 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COL4A5 | ZCRB1 | 0.789343 | 3 | 0 | 3 |
| COL4A5 | OCIAD2 | 0.77878 | 3 | 0 | 3 |
| COL4A5 | COL4A6 | 0.77119 | 13 | 0 | 13 |
| COL4A5 | DNAJC18 | 0.757843 | 3 | 0 | 3 |
| COL4A5 | CASC4 | 0.741351 | 3 | 0 | 3 |
| COL4A5 | DOCK11 | 0.733429 | 4 | 0 | 4 |
| COL4A5 | GEM | 0.727543 | 3 | 0 | 3 |
| COL4A5 | LAMC1 | 0.725696 | 11 | 0 | 10 |
| COL4A5 | FBN1 | 0.722463 | 7 | 0 | 7 |
| COL4A5 | TPBG | 0.721345 | 11 | 0 | 11 |
| COL4A5 | SPOPL | 0.72112 | 4 | 0 | 4 |
| COL4A5 | FILIP1 | 0.719619 | 3 | 0 | 3 |
| COL4A5 | CHST15 | 0.717023 | 11 | 0 | 11 |
| COL4A5 | NAP1L5 | 0.713758 | 3 | 0 | 3 |
| COL4A5 | LCLAT1 | 0.71029 | 4 | 0 | 4 |
| COL4A5 | SLC45A4 | 0.709658 | 3 | 0 | 3 |
| COL4A5 | SNAPC2 | 0.707715 | 3 | 0 | 3 |
| COL4A5 | NME4 | 0.699793 | 8 | 0 | 7 |
| COL4A5 | NFE2L1 | 0.691312 | 11 | 0 | 11 |
| COL4A5 | TTC7B | 0.691132 | 7 | 0 | 6 |
For details and further investigation, click here
