| Full name: cysteine rich transmembrane module containing 1 | Alias Symbol: ORF1-FL49 | ||
| Type: protein-coding gene | Cytoband: 5q31.3 | ||
| Entrez ID: 84418 | HGNC ID: HGNC:30239 | Ensembl Gene: ENSG00000120306 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CYSTM1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CYSTM1 | 84418 | 224707_at | 0.2349 | 0.7610 | |
| GSE26886 | CYSTM1 | 84418 | 224707_at | 1.9120 | 0.0000 | |
| GSE45670 | CYSTM1 | 84418 | 224707_at | 0.1426 | 0.6209 | |
| GSE53622 | CYSTM1 | 84418 | 94522 | 0.3121 | 0.0599 | |
| GSE53624 | CYSTM1 | 84418 | 94522 | 0.5067 | 0.0000 | |
| GSE63941 | CYSTM1 | 84418 | 224707_at | 0.7405 | 0.2239 | |
| GSE77861 | CYSTM1 | 84418 | 224707_at | 1.3641 | 0.0020 | |
| SRP007169 | CYSTM1 | 84418 | RNAseq | 1.8265 | 0.0001 | |
| SRP008496 | CYSTM1 | 84418 | RNAseq | 1.4410 | 0.0000 | |
| SRP064894 | CYSTM1 | 84418 | RNAseq | 0.5410 | 0.0420 | |
| SRP133303 | CYSTM1 | 84418 | RNAseq | 0.8345 | 0.0022 | |
| SRP159526 | CYSTM1 | 84418 | RNAseq | 0.7449 | 0.1159 | |
| SRP193095 | CYSTM1 | 84418 | RNAseq | -1.7707 | 0.0017 | |
| SRP219564 | CYSTM1 | 84418 | RNAseq | 0.5470 | 0.3566 |
Upregulated datasets: 4; Downregulated datasets: 1.
Survival by CYSTM1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CYSTM1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CYSTM1 | 84418 | 3 | 11 | 16 | |
| GSE20123 | CYSTM1 | 84418 | 4 | 11 | 15 | |
| GSE43470 | CYSTM1 | 84418 | 4 | 8 | 31 | |
| GSE46452 | CYSTM1 | 84418 | 0 | 27 | 32 | |
| GSE47630 | CYSTM1 | 84418 | 0 | 20 | 20 | |
| GSE54993 | CYSTM1 | 84418 | 9 | 1 | 60 | |
| GSE54994 | CYSTM1 | 84418 | 2 | 14 | 37 | |
| GSE60625 | CYSTM1 | 84418 | 0 | 0 | 11 | |
| GSE74703 | CYSTM1 | 84418 | 3 | 6 | 27 | |
| GSE74704 | CYSTM1 | 84418 | 3 | 5 | 12 | |
| TCGA | CYSTM1 | 84418 | 4 | 37 | 55 |
Total number of gains: 32; Total number of losses: 140; Total Number of normals: 316.
Somatic mutations of CYSTM1:
Generating mutation plots.
Highly correlated genes for CYSTM1:
Showing top 20/359 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CYSTM1 | SYT1 | 0.7894 | 3 | 0 | 3 |
| CYSTM1 | PPP1R35 | 0.7446 | 3 | 0 | 3 |
| CYSTM1 | POP7 | 0.739912 | 3 | 0 | 3 |
| CYSTM1 | STK3 | 0.735897 | 3 | 0 | 3 |
| CYSTM1 | AIP | 0.734147 | 4 | 0 | 4 |
| CYSTM1 | COPRS | 0.733127 | 5 | 0 | 4 |
| CYSTM1 | ENKD1 | 0.730703 | 3 | 0 | 3 |
| CYSTM1 | ITGA5 | 0.727655 | 3 | 0 | 3 |
| CYSTM1 | MACF1 | 0.722691 | 4 | 0 | 3 |
| CYSTM1 | PLOD3 | 0.713546 | 4 | 0 | 4 |
| CYSTM1 | SCYL1 | 0.71158 | 3 | 0 | 3 |
| CYSTM1 | PKIG | 0.71063 | 3 | 0 | 3 |
| CYSTM1 | SLC39A14 | 0.708942 | 6 | 0 | 6 |
| CYSTM1 | IFITM1 | 0.706718 | 3 | 0 | 3 |
| CYSTM1 | UBB | 0.706054 | 4 | 0 | 4 |
| CYSTM1 | FXR1 | 0.70125 | 3 | 0 | 3 |
| CYSTM1 | RHOQ | 0.699815 | 4 | 0 | 4 |
| CYSTM1 | FTO | 0.698499 | 3 | 0 | 3 |
| CYSTM1 | TUG1 | 0.695056 | 3 | 0 | 3 |
| CYSTM1 | CALML4 | 0.685418 | 3 | 0 | 3 |
For details and further investigation, click here
